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New type of immunotherapy could change the treatment plan for triple-negative breast cancer

Triple-negative breast cancer is one of the most aggressive cancers. The name tells the story: It lacks the three main targets that make other types of breast cancers more treatable with powerful therapies.

22 Oct 2025

Hunger and hormones drive aggression in mice

Researchers at the Francis Crick Institute have found that hunger can make virgin female mice aggressive towards pups, but only in certain hormonal states.

22 Oct 2025

New study solves lung transplant rejection mystery

More than 50% of lung-transplant recipients experience a rejection of their new lung within five years of receiving it, yet the reason why this is such a prevalent complication has remained a medical mystery.

22 Oct 2025

Study sheds light on how aging unfolds in pets and humans

Scientists have long sought measurable signs in the body, called biomarkers, that reliably reveal our biological age or predict future health issues.

22 Oct 2025

Foot or ankle injuries in professional football players may increase risk of osteoarthritis

A new paper in Rheumatology, published by Oxford University Press, finds that retired UK male professional football players who reported foot or ankle injuries during their careers were more likely to develop osteoarthritis in retirement.

22 Oct 2025

New computer model lets researchers simulate how brain circuits make decisions

Every day, your brain makes thousands of decisions under uncertainty. Most of the time, you guess right. When you don't, you learn. But when the brain's ability to judge context or assign meaning falters, thoughts and behavior can go astray.

22 Oct 2025

Understanding the neural mechanisms behind food choices

Feeding in mammals is controlled by a complex neural system. Although several key neural pathways related to total calorie intake have been extensively studied, it is still unclear how food choices are regulated and how they influence overall feeding behavior.

22 Oct 2025

Rare case of pancreatic Hodgkin lymphoma is often misdiagnosed as pancreatic adenocarcinoma

A new case report was published in Volume 12 of Oncoscience on October 6, 2025, titled "A peculiar case of primary lymphoma of pancreas: A rare presentation of Hodgkin lymphoma."

22 Oct 2025

Nuclear binding protein identified as key contributor to trisomy 21-related CHDs

Three copies of chromosome 21 causes Down syndrome (DS), and roughly half of children born each year in the United States with DS-approximately 2,600-also have congenital heart defects (CHDs).

22 Oct 2025

Pathogenic bacteria can block gut’s natural defense to spread infection

When harmful bacteria that cause food poisoning, such as E. coli, invade through the digestive tract, gut cells usually fight back by pushing infected cells out of the body to stop the infection from spreading.

22 Oct 2025

HMGN1 gene linked to heart problems in people with Down syndrome

Nearly half of all babies born with Down syndrome face congenital heart defects, often involving serious malformations that require surgery in the first months of life.

22 Oct 2025

Study forces a textbook rewrite on cell division

Scientists at the Ruđer Bošković Institute (RBI) in Zagreb, Croatia, have discovered that the protein CENP-E, long believed to act as a motor dragging chromosomes into place during cell division, in fact plays a completely different role in chromosome movement.

22 Oct 2025

Analysis highlights the differing physical side effects of antidepressants

Antidepressants can differ widely in how they physically affect the body, including around a 4 kg difference in weight change between certain drugs (approximately 2.5 kg weight loss from agomelatine and 2kg weight gain from maprotiline), confirms a systematic review and meta-analysis published in The Lancet.

22 Oct 2025

Anaphylaxis antidote underprescribed for schoolchildren in England

Less than half of schoolchildren in England who are at risk of a serious and potentially life-threatening allergic reaction (anaphylaxis) to food were prescribed the antidote-an adrenaline [epinephrine] autoinjector, or AAI for short-finds an analysis of national prescribing data, published online in the Archives of Disease in Childhood.

22 Oct 2025

Researchers gain new insights into aging based on studies in dogs

Lab-based studies have provided lots of information on the biology of aging, but it's unclear how lab discoveries apply to aging in the real world. Research in Aging Cell provides insights into aging based on studies in dogs.

22 Oct 2025

Dreams happen beyond REM sleep, analysis shows

An international consortium of researchers has created the largest-ever database compiling records of brain activity during sleep and dream reports.

22 Oct 2025

Researchers highlight ethical implications of clinical trial terminations

The termination of thousands of federal grants that fund clinical trials threatens to reverse substantial progress in understanding and treating the health challenges of marginalized populations, particularly children and adolescents who are already underrepresented in research.

22 Oct 2025

Abstinence or limiting alcohol intake may lead to clinically meaningful blood pressure reductions

Light-to-moderate alcohol consumption is associated with increases in blood pressure (BP) and stopping drinking – even drinking less – may lead to clinically meaningful BP reductions, according to a study published today in JACC, the flagship journal of the American College of Cardiology.

22 Oct 2025

People with multiple sclerosis found to have dysbiotic oral microbiome

With ads everywhere for pro- or pre-biotic foods and supplements, most people are familiar with the gut microbiome-the trillions of bacteria, fungi, and viruses that colonize our digestive tract-and the idea that keeping our gut microbiome healthy improves our overall health.

22 Oct 2025

First-generation antihistamines increase delirium risk in older hospitalized patients

An analysis in the Journal of the American Geriatrics Society reveals that older inpatients admitted to physicians who prescribe higher amounts of first-generation antihistamines face an elevated risk of delirium while in the hospital.

22 Oct 2025

Medical Research News

New type of immunotherapy could change the treatment plan for triple-negative breast cancer

Hunger and hormones drive aggression in mice

New study solves lung transplant rejection mystery

Study sheds light on how aging unfolds in pets and humans

Foot or ankle injuries in professional football players may increase risk of osteoarthritis

New computer model lets researchers simulate how brain circuits make decisions

Understanding the neural mechanisms behind food choices

Rare case of pancreatic Hodgkin lymphoma is often misdiagnosed as pancreatic adenocarcinoma

Nuclear binding protein identified as key contributor to trisomy 21-related CHDs

Pathogenic bacteria can block gut’s natural defense to spread infection

HMGN1 gene linked to heart problems in people with Down syndrome

Study forces a textbook rewrite on cell division

Analysis highlights the differing physical side effects of antidepressants

Anaphylaxis antidote underprescribed for schoolchildren in England

Researchers gain new insights into aging based on studies in dogs

Dreams happen beyond REM sleep, analysis shows

Researchers highlight ethical implications of clinical trial terminations

Abstinence or limiting alcohol intake may lead to clinically meaningful blood pressure reductions

People with multiple sclerosis found to have dysbiotic oral microbiome

First-generation antihistamines increase delirium risk in older hospitalized patients

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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