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New gene therapy reverses symptoms of SYNGAP1-related disorders in mice

In an exciting scientific first, researchers at the Allen Institute successfully designed a new gene therapy that reversed symptoms related to SYNGAP1-related disorders (SRD) in mice.

9 Oct 2025

Third-sector services prove more effective at helping the long-term unemployed in deprived areas

New research reveals that 'third-sector' services, such as those run by housing associations, are far more effective than government work programmes at helping the long-term unemployed in deprived areas.

9 Oct 2025

Women show peak cognitive performance during ovulation but exercise matters more

Women performed best on cognitive tests during ovulation but physical activity level had a stronger influence on brain function, according to a new study from researchers at UCL.

9 Oct 2025

Cleveland Clinic team uncovers genetic link to osteosarcoma

Researchers at Cleveland Clinic Children's have helped identify a previously unknown gene that increases the risk of developing osteosarcoma, the most common type of malignant bone tumor in children and young adults.

9 Oct 2025

Breakthrough in cancer therapy targets key protein interaction to suppress tumors

Researchers at the Francis Crick Institute and Vividion Therapeutics have identified chemical compounds that can precisely block the interaction between the major cancer-driving gene RAS, and a key pathway for tumor growth.

9 Oct 2025

Shame prevents people from seeking dental treatment and worsens oral health inequalities

Shame can lead people to avoid getting treatment for dental issues, potentially worsening oral health inequalities, a new study warns.

9 Oct 2025

First global standard published to measure outcomes in dengue treatment trials

The first global standard which harmonizes what outcomes to measure in dengue treatment trials has been published this week in The Lancet Infectious Diseases. Co-led by researchers at King's and the University of Oxford, this solves a longstanding discrepancy in terms of what is measured in these trials.

9 Oct 2025

Nanoparticle vaccine shows promise in preventing multiple cancers in mice

A study led by University of Massachusetts Amherst researchers demonstrates that their nanoparticle-based vaccine can effectively prevent melanoma, pancreatic and triple-negative breast cancer in mice.

9 Oct 2025

Errors in EPG5 gene implicated in rare infant condition and adult neurodegenerative diseases

Errors in a gene known to cause a serious neurodevelopmental condition in infants are also linked to the development of Parkinson's disease in adolescence and adulthood, according to new research.

9 Oct 2025

Socially enriched environments linked to better memory and cognitive flexibility in aged rats

A new research paper was published in Volume 17, Issue 9 of Aging-US on August 22, 2025, titled, "The impact of long-term social housing on biconditional association task performance and neuron ensembles in the anterior cingulate cortex and the hippocampal CA3 region of aged rats."

9 Oct 2025

Watching short inspirational videos provides stress relief just like meditation

Watching short inspirational videos may be just as effective at reducing stress as meditation, according to research published by the American Psychological Association.

9 Oct 2025

Newborn genomic screening may detect hundreds of additional childhood conditions

Adding genomic sequencing to newborn blood screening would detect hundreds of additional childhood conditions, providing much earlier diagnosis and treatment, according to a new study. A baby's genome, which stays with them for life, could also be re-examined if a health issue arises during their lifetime.

9 Oct 2025

Quitting smoking after cancer diagnosis significantly extends survival

Around 25% of people with cancer in the U.S. are active smokers when they are diagnosed, and studies have found that many of them continue to smoke during treatment.

9 Oct 2025

GLP-1 therapeutics may have the potential to treat alcohol and drug addiction

A popular class of therapies for treating diabetes and obesity may also have the potential to treat alcohol and drug addiction, according to a new paper published in the Journal of the Endocrine Society.

9 Oct 2025

Diabetic teens with poor glycemic control more likely to develop neuropathy in adulthood

Poor blood sugar control in adolescence increases the risk of painful future complications for people with type 1 diabetes, research co-led by University of Michigan suggests.

9 Oct 2025

Engineered virus therapy triggers powerful immune responses in glioblastoma

A new study led by Break Through Cancer's Accelerating Glioblastoma (GBM) Therapies Through Serial Biopsies TeamLab has revealed that an engineered virus therapy, CAN-3110, triggered powerful immune responses deep inside glioblastoma tumors that were invisible to standard imaging like MRI, according to early analyses of two patients with recurrent GBM.

9 Oct 2025

Air pollution plays a significant role in the development of metabolic disorders

Long-term exposure to fine air pollution can impair metabolic health by disrupting the normal function of brown fat in mice. A study co-led by the University of Zurich shows that this occurs through complex changes in gene regulation driven by epigenetic mechanisms.

9 Oct 2025

Medical Research News

New gene therapy reverses symptoms of SYNGAP1-related disorders in mice

Third-sector services prove more effective at helping the long-term unemployed in deprived areas

Women show peak cognitive performance during ovulation but exercise matters more

Cleveland Clinic team uncovers genetic link to osteosarcoma

Breakthrough in cancer therapy targets key protein interaction to suppress tumors

Shame prevents people from seeking dental treatment and worsens oral health inequalities

First global standard published to measure outcomes in dengue treatment trials

Nanoparticle vaccine shows promise in preventing multiple cancers in mice

Errors in EPG5 gene implicated in rare infant condition and adult neurodegenerative diseases

Socially enriched environments linked to better memory and cognitive flexibility in aged rats

Watching short inspirational videos provides stress relief just like meditation

Newborn genomic screening may detect hundreds of additional childhood conditions

Quitting smoking after cancer diagnosis significantly extends survival

GLP-1 therapeutics may have the potential to treat alcohol and drug addiction

Diabetic teens with poor glycemic control more likely to develop neuropathy in adulthood

Engineered virus therapy triggers powerful immune responses in glioblastoma

Air pollution plays a significant role in the development of metabolic disorders

Study reveals how RfaH protein acts as a protective shield for bacterial genes

Healthy eating may come at the expense of exploited workers

Hormone replacement therapy may reverse menopause-related immune changes

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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