Gene News and Research

Latest Gene News and Research

Sickle cell disease patients willing to accept high risks for gene therapy cure

Individuals living with severe sickle cell disease (SCD) are highly interested in new, potentially curative gene therapy treatments and are willing to accept associated risks for a chance at a cure, according to a study published today in Blood Advances.

31 Oct 2023

Study reveals how SARS-CoV-2 alters mitochondria, leading to energy outages and organ failure

The lungs were once at the forefront of SARS-Cov-2 research, but as reports of organ failure and other serious complications poured in, scientists set out to discover how and why the respiratory virus was causing serious damage to the body's major organs, including the lungs.

31 Oct 2023

New drug gets FDA approval for the treatment of common genetic disease in young boys

A new drug developed by professors from the School of Pharmacy and Pharmaceutical Sciences at Binghamton University has received Food and Drug Administration (FDA) approval for the treatment of patients with Duchenne muscular dystrophy (DMD), a common genetic disease that mostly affects young boys.

31 Oct 2023

Osteoarthritis may be treatable and reversible, new study shows

Current osteoarthritis treatment manages symptoms rather than addressing the underlying disease, but a new University of Adelaide study has shown the condition may be treatable and reversible.

31 Oct 2023

Unsupervised genome-wide variant effect predictor based on pretraining of DNA language models

The Genomic Pre-trained Network (GPN), a multispecies model developed to learn genome-wide variant effects.

31 Oct 2023

Axon Biology & The Future of Drug Discovery: A Deep Dive with Dr Federico Dajas-Bailador

News-Medical sits down with Dr. Federico Dajas-Bailador, a leading expert in axon biology and drug discovery.

From ELRIG (UK) Ltd. 31 Oct 2023

Broken String Biosciences’ INDUCE-seq platform demonstrates impact of structural DNA changes on specificity of CRISPR-Cas9 gene editing

Broken String Biosciences today announced that its INDUCE-seq™ DNA break-mapping technology had been used in a peer-reviewed research paper to characterize off-target effects of CRISPR-Cas9 gene editing resulting from changes in DNA topology.

From Broken String Biosciences 31 Oct 2023

New MECP2 gene variant identified and characterized in Rett syndrome

Rett syndrome is a rare devastating neurological disorder that primarily affects young girls and manifests as an impaired ability to walk and talk, along with characteristic 'hand-wringing' movements, seizures, and cognitive disability.

30 Oct 2023

Study uncovers interplay of lifestyle choices and DNA methylation in gastric neoplasia risk

A new paper in The Lancet eBioMedicine explores whether these changes predict the future risk of stomach tumors and how epigenetic changes interact with environmental and lifestyle factors in this process.

30 Oct 2023

New blood test revolutionizes early cancer detection in Li-Fraumeni Syndrome patients

Canadian researchers develop a cell-free DNA-based multimodal assay for early cancer detection in patients with Li-Fraumeni Syndrome, a high-cancer-risk condition. The assay outperforms conventional methods, promising more sensitive and less invasive cancer surveillance.

29 Oct 2023

Loss of structural protein ACTL7B blocks spermatogenesis in male mice

Mature spermatozoa are characterized by an head, midpiece and a long tail for locomotion. Now, researchers from the University Hospital Bonn (UKB) and the Transdisciplinary Research Unit "Life & Health" at the University of Bonn have found that a loss of the structural protein ACTL7B blocks spermatogenesis in male mice.

27 Oct 2023

UC San Diego Health and Tri-City partnership aims to expand, transform access to health care

After open public discussion and a unanimous board vote, Tri-City Healthcare District ("Tri-City" or "District") announced yesterday that UC San Diego Health has been selected as the District's future health care partner.

27 Oct 2023

Genetics and sedimentology combined to refine cyanobacteria biomarker diagnostics

Cyanobacteria are a key species in Earth's history, as they introduced atmospheric oxygen for the first time. The analysis of their evolution therefore provides important insights into the formation of modern aerobic ecosystems.

27 Oct 2023

Study highlights a “sunscreen paradox” and the false sense of security against skin cancer

Sunscreen usage is climbing, but so are melanoma and skin cancer rates: this, researchers say, is the sunscreen paradox.

27 Oct 2023

Novel replacement strategy holds promise for the treatment of various genetic disorders

Severe Combined Immunodeficiencies (SCIDs) are a group of debilitating primary immunodeficiency disorders, primarily caused by genetic mutations that disrupt T-cell development. SCID can also affect B-cell and natural killer cell function and counts.

27 Oct 2023

Single-cell proteomics – when mass spectrometry revolutionizes biomedical research

In the latest episode of the OMG Omx podcast, Bruker's Kate Stumpo talks to Nikolai Slavov about the incredible potential of mass spectrometry proteomics in biomedical research.

From Bruker Life Sciences Mass Spectrometry 27 Oct 2023

Is retroelement-based gene editing a safer alternative to CRISPR-Cas approaches?

In a Perspective, Stephen Tang and Samuel Sternberg discuss retroelement-based gene editing as a safer alternative to CRISPR-Cas approaches.

26 Oct 2023

Somatic mutations in the skin not responsible for the start or spread of psoriasis

Psoriasis - a chronic skin condition - is not caused or spread by spontaneous genetic mutations in the skin, new research suggests.

26 Oct 2023

Genomic screening encourages people with hemochromatosis to seek treatment and relevant management

Genomic screening to identify hemochromatosis - a disorder that causes iron levels in the body to rise to dangerous levels - encourages people with the condition to seek treatment and ongoing management, a Geisinger study found.

26 Oct 2023

New bioreactor could accelerate access to cancer-killing immunotherapy

A new tool to rapidly grow cancer-killing white blood cells could advance the availability of immunotherapy, a promising therapy which harnesses the power of the body's immune response to target cancer cells.

26 Oct 2023

Gene News and Research

Latest Gene News and Research

Sickle cell disease patients willing to accept high risks for gene therapy cure

Study reveals how SARS-CoV-2 alters mitochondria, leading to energy outages and organ failure

New drug gets FDA approval for the treatment of common genetic disease in young boys

Osteoarthritis may be treatable and reversible, new study shows

Unsupervised genome-wide variant effect predictor based on pretraining of DNA language models

Axon Biology & The Future of Drug Discovery: A Deep Dive with Dr Federico Dajas-Bailador

Broken String Biosciences’ INDUCE-seq platform demonstrates impact of structural DNA changes on specificity of CRISPR-Cas9 gene editing

New MECP2 gene variant identified and characterized in Rett syndrome

Study uncovers interplay of lifestyle choices and DNA methylation in gastric neoplasia risk

New blood test revolutionizes early cancer detection in Li-Fraumeni Syndrome patients

Loss of structural protein ACTL7B blocks spermatogenesis in male mice

UC San Diego Health and Tri-City partnership aims to expand, transform access to health care

Genetics and sedimentology combined to refine cyanobacteria biomarker diagnostics

Study highlights a “sunscreen paradox” and the false sense of security against skin cancer

Novel replacement strategy holds promise for the treatment of various genetic disorders

Single-cell proteomics – when mass spectrometry revolutionizes biomedical research

Is retroelement-based gene editing a safer alternative to CRISPR-Cas approaches?

Somatic mutations in the skin not responsible for the start or spread of psoriasis

Genomic screening encourages people with hemochromatosis to seek treatment and relevant management

New bioreactor could accelerate access to cancer-killing immunotherapy

Genomics - Industry Focus eBook (2nd edition) eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production