Gene News and Research

Latest Gene News and Research

A microbiota-driven mechanism underlies severity of leishmaniasis infection

In a recent study posed to the medRxiv* preprint server, researchers in Brazil and the United States investigated the probable impact of the skin microbiome microbiota on the outcomes of cutaneous leishmaniasis.

8 Feb 2023

Newest vitamin B3 family member has beneficial effects on mitochondria in the human muscle

The newest vitamin B3 family member, nicotinamide riboside (NR) has been found to have beneficial effects on mitochondria in the human muscle.

8 Feb 2023

Macrophages suppress Escherichia coli LF82 Gally prophage lytic cycle

Researchers analyze prophages of the LF82 strain of adherent-invasive Escherichia coli to better understand their behavior in vitro and within macrophages.

8 Feb 2023

COVID-19 vaccination increases saliva antibody levels after asymptomatic infection

Researchers correlate SARS-CoV-2 load and neutralizing capacity of all saliva immunoglobulins isotypes in asymptomatic individuals.

8 Feb 2023

Cleveland Clinic researchers launch the next step in triple-negative breast cancer vaccine study

Cleveland Clinic researchers have launched the next step in their novel study of a vaccine aimed at preventing triple-negative breast cancer, the most aggressive and lethal form of the disease.

8 Feb 2023

The possible role of the endometrial microbiome as an immune modulator in the phase of implantation and during pregnancy

Researchers reviewed the impact of endometrial microbiota on immune tolerance during pregnancy.

8 Feb 2023

Study evaluates benefits of implementing a pharmacogenetic panel before drug initiation

In a recent study published in The Lancet, researchers performed an implementation study of a 12-gene pharmacogenetic panel across seven European countries to investigate whether a gene-drug interaction guidedinteraction-guided prescribing strategy could prevent its adverse reactions.

8 Feb 2023

UC researcher aims to develop better treatments for KRAS-mutated pancreatic cancer

Pancreatic cancer diagnoses are increasing more rapidly than any other cancer type while remaining one of the most deadly cancers.

7 Feb 2023

Bivalent boosters provide additional protection from BA.5, XBB, and XBB.1.5

In a recent Morbidity and Mortality Weekly Report (MMWR) published on the United States Center for Disease Control and Prevention (US-CDC) website, researchers analyzed data from the Increasing Community Access to Testing (ICATT), a nationwide pharmacy program run in the US for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing.

7 Feb 2023

Increase in resistant Shigella infections among men who have sex with men

Researchers report a rise in Shigella flexneri type 2a infections in men who have sexual intercourse with men in England from September 2021 onward.

7 Feb 2023

USC researchers identify two promising avenues for developing new ALS treatments

Each year in the U.S., 5,000 patients receive a diagnosis of ALS, an incurable neurodegenerative disease that will likely kill them within two to five years.

7 Feb 2023

Lymphatic vessels may be a previously unrecognized source of blood cells

Scientists investigating the causes of lymphoedema have made a major discovery, revealing that lymphatic vessels can produce red and white blood cells.

7 Feb 2023

Study highlights the emergence of S. cerevisiae as an opportunistic fungal pathogen in immunosuppressed patients presenting several severe comorbidities

Researchers from Brazil presented a fatal case of a patient developing Saccharomyces cerevisiae infection and succumbing to septic shock after contracting and recovering from a SARS-CoV-2 infection.

7 Feb 2023

Integrated NGS system can deliver accurate, genomics-based diagnoses to accelerate treatment for myeloid neoplasms

Identifying recurrent genetic alterations in myeloid neoplasms has improved diagnosis and expanded targeted treatments available to patients. However, treatment initiation can be delayed by the variable and lengthy turnaround times involved in testing for these alterations.

7 Feb 2023

Evonetix closes $24 million USD (£20 million) financing

Funding will enable development of DNA synthesis chip technology to commercial scale.

From Evonetix 7 Feb 2023

Newly identified gene signature helps assess cancer risk and optimize treatment

In a paper published in PNAS, Maureen Murphy, Ph.D., Deputy Director of Wistar's Ellen and Ronald Caplan Cancer Center and Ira Brind Professor and Program Leader in the Molecular & Cellular Oncogenesis Program, and team have identified a gene signature that accurately predicts the functioning of P53 variants, important information to assessing cancer risk and optimizing choices for cancer therapeutics.

7 Feb 2023

Lonza delivers strong 2022 performance with 15.1% CER sales growth and 32.1% CORE EBITDA margin

Lonza has reported sales of CHF 6.2 billion, sales growth of 15.0% AER (15.1% CER), and CHF 2.0 billion CORE EBITDA, resulting in a margin of 32.1%. These robust financial results are driven by strong underlying business performance and a COVID-related sales peak in 2022 which enhanced both sales and margin.

From Lonza 7 Feb 2023

Gene News and Research

Latest Gene News and Research

A microbiota-driven mechanism underlies severity of leishmaniasis infection

Newest vitamin B3 family member has beneficial effects on mitochondria in the human muscle

Macrophages suppress Escherichia coli LF82 Gally prophage lytic cycle

COVID-19 vaccination increases saliva antibody levels after asymptomatic infection

Cleveland Clinic researchers launch the next step in triple-negative breast cancer vaccine study

The possible role of the endometrial microbiome as an immune modulator in the phase of implantation and during pregnancy

Study evaluates benefits of implementing a pharmacogenetic panel before drug initiation

UC researcher aims to develop better treatments for KRAS-mutated pancreatic cancer

Bivalent boosters provide additional protection from BA.5, XBB, and XBB.1.5

Increase in resistant Shigella infections among men who have sex with men

USC researchers identify two promising avenues for developing new ALS treatments

Lymphatic vessels may be a previously unrecognized source of blood cells

Study highlights the emergence of S. cerevisiae as an opportunistic fungal pathogen in immunosuppressed patients presenting several severe comorbidities

Integrated NGS system can deliver accurate, genomics-based diagnoses to accelerate treatment for myeloid neoplasms

Evonetix closes $24 million USD (£20 million) financing

Newly identified gene signature helps assess cancer risk and optimize treatment

Lonza delivers strong 2022 performance with 15.1% CER sales growth and 32.1% CORE EBITDA margin

New research may explain why some patients suffer from long-COVID

A novel multiplexed assay to diagnose Mpox and other viruses

Researchers identify a new genetic risk factor for age-related macular degeneration

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson