Gene News and Research

Latest Gene News and Research

New genetic discovery improves understanding of congenital heart disease

A new study led by the Masonic Medical Research Institute published in the journal Cells shows for the first time that a particular gene, called VGLL4, is required for embryo development but is dispensable for myocardial growth.

21 Sep 2022

Mutation in newly discovered small protein linked to increase in Alzheimer's disease risk

A mutation in a newly discovered small protein is connected to a significant increase in the risk for Alzheimer's disease, expanding the known gene targets for the disease and presenting a new potential avenue for treatment, according to a new USC study.

21 Sep 2022

New antiviral mechanism of action for an FDA-approved thiopurine known as 6-thioguanine

Researchers described a novel antiviral mechanism of action for an FDA (food and drug administration)-approved thiopurine known as 6-thioguanine (6-TG).

21 Sep 2022

Common genetic variants of APOE associated with COVID mortality

It may be the most baffling quirk of COVID: What manifests as minor, flu-like symptoms in some individuals spirals into severe disease, disability, and even death in others.

21 Sep 2022

Why fatigue from long COVID goes beyond simply feeling tired

In a recent study posted to the medRxiv* preprint server, researchers in the Netherlands examined the role of inflammatory genes, cytotoxic T-lymphocytes (CD8+ T cells), and pro-inflammatory cytokines in long-lasting severe fatigue experienced by a large number of coronavirus disease 2019 (COVID-19) patients.

21 Sep 2022

Evidence A.2 lineage of monkeypox is mutating

In a recent study posted to the bioRxiv* preprint server, a team of researchers from India analyzed the whole genome sequences of the monkeypox virus isolated from monkeypox patients with and without international travel histories to understand the phylogenetic relations and genomic evolution of the virus that could contribute to higher transmission rates.

21 Sep 2022

NPDPSC at Case Western Reserve University to receive CDC funding for better understanding of prion diseases

The National Prion Disease Pathology Surveillance Center at Case Western Reserve University will receive up to $20 million in funding as part of a grant renewal from the Centers for Disease Control and Prevention (CDC) to better understand how and why prion diseases––degenerative brain conditions found in both humans and animals - develop and spread.

20 Sep 2022

Humanized zebrafish could aid in the search for MS drugs

The zebrafish should be known to many aquarium enthusiasts mainly because of its striking pigmentation. However, the characteristic black-blue stripes, to which the animal owes its name, only form over time.

20 Sep 2022

Epigenetic treatment can promote neuronal regrowth in the spinal cord after injury

Currently, spinal cord injury does not have any effective treatments; physical rehabilitation can help patients regain some mobility, but for severe cases the outcomes are extremely limited by the failure of spinal neurons to regenerate naturally after injury.

20 Sep 2022

Epigenetic gene silencing found to be a predictive factor for aggressive breast and ovarian cancer

In a recent study published in JAMA Oncology, investigators from the University of Bergen, in collaboration with the Women's Health Initiative study in the US, reported epigenetic gene silencing in normal tissue to be a predictive factor for triple-negative breast cancer (TNBC) as well as high-grade serous ovarian cancer (HGSOC).

20 Sep 2022

Study identifies genetic variation linked with posterior urethral valves in males

Genetic variation affecting developmental genes not previously linked to urethral development may contribute to a congenital condition that is the most common cause of kidney failure in young males, a study published today in eLife suggests.

20 Sep 2022

Scientists find evidence of fungal organism Histoplasma capsulatum in Antarctica

...

20 Sep 2022

Coronavirus shedding by straw-colored fruit bats in Africa with potential for zoonotic pathogen transmission

In a recent study published in the journal PLoS ONE, researchers evaluated the temporal shedding patterns of coronavirus (CoV) in Eidolon helvum, the straw-colored fruit bat.

20 Sep 2022

Study identifies common genetic variants associated with musical beat synchronization

The first large-scale genomic study of musicality - published on the cover of today's Nature Human Behaviour - identified 69 genetic variants associated with beat synchronization, meaning the ability to move in synchrony with the beat of music.

19 Sep 2022

COVID-19 during pregnancy damages the placenta's immune response to further infections

If a woman contracts COVID-19 during her pregnancy, the infection, even if it's mild, damages the placenta's immune response to further infections, a UW Medicine-led study has found.

19 Sep 2022

Environmental surveillance detects poliovirus type 2 outbreaks in Israel

The wastewater environmental surveillance conducted in Jerusalem, Israel, has detected an increasing population of poliovirus type 2. Furthermore, these viral isolates are associated with vaccine-derived viral strains.

19 Sep 2022

Intact autophagic vacuoles found to be indispensable in mediating competitive elimination of cancer cells

Elimination of transformed cells that can initiate cancer is necessary to maintain tissue integrity. In a new study, scientists from Tokyo University of Science show how this mechanism is regulated by the cellular process "autophagy."

19 Sep 2022

Researchers identify a genetic defect in alveolar macrophages that causes lung disease

New discovery on the causes of PAP lung disease can also offer solutions for treating obesity and heart disease. The research group of Associate Professor Alexander Mildner at the University of Turku, Finland, identified a genetic defect that causes the accumulation of lipids in the pulmonary alveoli.

19 Sep 2022

Study reveals pathological mechanisms of synaptic dysfunction in patients with Huntington's disease

Huntington's disease (HD) is a hereditary brain disease caused by a mutation in the huntingtin gene. HD is a neurodegenerative disease without a cure that, after the onset of the disease at around 40 years of age, causes changes in personality and symptoms of dementia along with uncontrollable convulsive movements, ultimately leading to death.

19 Sep 2022

Is aspirin linked to higher rates of survival for cancer patients?

Researchers discussed the existing evidence on the use of acetylsalicylic acid (aspirin) in cancer treatment.

19 Sep 2022

Gene News and Research

Latest Gene News and Research

New genetic discovery improves understanding of congenital heart disease

Mutation in newly discovered small protein linked to increase in Alzheimer's disease risk

New antiviral mechanism of action for an FDA-approved thiopurine known as 6-thioguanine

Common genetic variants of APOE associated with COVID mortality

Why fatigue from long COVID goes beyond simply feeling tired

Evidence A.2 lineage of monkeypox is mutating

NPDPSC at Case Western Reserve University to receive CDC funding for better understanding of prion diseases

Humanized zebrafish could aid in the search for MS drugs

Epigenetic treatment can promote neuronal regrowth in the spinal cord after injury

Epigenetic gene silencing found to be a predictive factor for aggressive breast and ovarian cancer

Study identifies genetic variation linked with posterior urethral valves in males

Scientists find evidence of fungal organism Histoplasma capsulatum in Antarctica

Coronavirus shedding by straw-colored fruit bats in Africa with potential for zoonotic pathogen transmission

Study identifies common genetic variants associated with musical beat synchronization

COVID-19 during pregnancy damages the placenta's immune response to further infections

Environmental surveillance detects poliovirus type 2 outbreaks in Israel

Intact autophagic vacuoles found to be indispensable in mediating competitive elimination of cancer cells

Researchers identify a genetic defect in alveolar macrophages that causes lung disease

Study reveals pathological mechanisms of synaptic dysfunction in patients with Huntington's disease

Is aspirin linked to higher rates of survival for cancer patients?

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson