Gene News and Research

Latest Gene News and Research

Rare genetic variants may raise risk of fatal arrhythmias in patients with less advanced coronary artery disease

Advanced coronary artery disease and the cardiac hypertrophy often associated with it is the most common cause of sudden cardiac death.

18 Jan 2022

New pathways responsible for hepatocellular carcinoma identified

Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer. It is one of leading causes of cancer-related deaths globally, with more than 700,000 new cases and 600,000 estimated HCC deaths each year.

18 Jan 2022

Study: Nearly 30% of people with blinding retinal disease can safely stop eye injection therapy

In a preliminary study of 106 people with "wet" age-related macular degeneration, Johns Hopkins Medicine researchers report that as many as a third of those with the blinding retinal disease may someday be able to safely stop eye injection therapy without further vision loss.

18 Jan 2022

Respiratory viruses lacking NS2 protein can be destroyed by the body's immune response

One viral protein could provide information to deter pneumonia causing the body's exaggerated inflammatory response to respiratory viruses, including the virus that causes COVID-19.

18 Jan 2022

Analyzing disease severity of SARS-CoV-2 Omicron variant using RNA dependent RNA polymerase target delay

In a new study, a team of researchers compared the severity of the SARS-CoV-2 Omicron variant to the Delta variant using the PCR proxy marker of RNA dependent RNA polymerase target delay.

18 Jan 2022

Exploring the viral dynamics of SARS-CoV-2 Omicron variant

In a new study, researchers posted findings in which they investigated the viral dynamics of the SARS-CoV-2 Omicron variant.

18 Jan 2022

Direct effect of SARS-CoV-2 on the kidney

Researchers infected human-induced pluripotent-stem-cell (iPSC)-derived kidney organoids with SARS-CoV-2 to study the virus's direct effect on the kidney.

18 Jan 2022

Study reveals a causal link between deficiency in Parkinson’s disease gene and reduced immunoaging

A Parkinson’s disease gene turns out to provide the key to modify diseases related to immunoaging.

18 Jan 2022

Study reveals a causal link between deficiency in Parkinson’s disease gene and reduced immunoaging

A Parkinson’s disease gene turns out to provide the key to modify diseases related to immunoaging.

18 Jan 2022

UniSA scientists make a surprising discovery in the origins of antibiotic-resistant gene

University of South Australia scientists have made a surprising discovery in the origins of an antibiotic-resistant gene previously thought to have been confined to Adelaide.

18 Jan 2022

An alternative mouse model of SARS-CoV-2 infection

Recently, a study has shown the possibility of repurposing hACE2 transgenic mice, primarily raised to study SARS-CoV, to support SARS-CoV-2 infection and pathogenesis.

17 Jan 2022

DPP4 protein: The connection between severe COVID-19 and diabetes

Researchers explore the relationship between DPP4 and diabetes targets in the management of COVID-19.

17 Jan 2022

Exploring the systemic infection of SARS-CoV-2 in a wild leopard in India

A new study focused on the pathomorphological and virological characterization of SARS-CoV-2 in naturally infected, wild Indian Leopard.

17 Jan 2022

Researchers investigate the role of a key component of the circadian clock in heart disease

Disrupting circadian rhythms, which change naturally on a 24-hour cycle, has been implicated in heart disease, but it is unclear how it leads to the condition.

17 Jan 2022

Study finds evidence to strongly implicate OAS1 as an effector gene influencing COVID-19 severity

Researchers demonstrated that this splice variant is likely to be the single nucleotide polymorphism responsible for the association at this locus.

17 Jan 2022

Dexamethasone shown to upregulate innate and adaptive immune responses in COVID-19 acute respiratory distress syndrome patients

In a new study, researchers used per protocol bronchoalveolar lavage fluid (BALF) samples after intubation to evaluate the transcriptomic profiles of the local pulmonary host responses during early-stage severe coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome (CARDS), non-COVID-19 ARDS, and sepsis.

17 Jan 2022

Study demonstrates that intra-host SARS-CoV-2 variants with reduced infectivity are developed during infection

A new paper discusses the appearance of quasi-species in a single host with prolonged infection, with different rates of infectivity and sensitivity to neutralization by antibodies elicited by the Pfizer vaccine or those present in convalescent plasma.

17 Jan 2022

Study identifies cellular receptors for alphaviruses shared across mosquitoes, humans, and animals

A new study led by researchers at Harvard Medical School has identified a set of cellular receptors for at least three related alphaviruses shared across mosquitoes, humans, and animals that host the virus.

17 Jan 2022

Researchers engineer enucleated cells to deliver therapeutics precisely to diseased tissues

Researchers at University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health report successfully removing the nucleus out of a type of ubiquitous cell, known as enucleation, then using the genetically engineered cell as a unique cargo-carrier to deliver therapeutics precisely to diseased tissues.

17 Jan 2022

Discovery opens up the possibility of pursuing new therapies for FOP

Fibrodysplasia ossificans progressiva (FOP) is a rare disease characterized by extensive bone growth outside of the normal skeleton that pre-empts the body's normal responses to even minor injuries. It results in what some term a "second skeleton," which locks up joint movement and could make it hard to breathe.

16 Jan 2022

Gene News and Research

Latest Gene News and Research

Rare genetic variants may raise risk of fatal arrhythmias in patients with less advanced coronary artery disease

New pathways responsible for hepatocellular carcinoma identified

Study: Nearly 30% of people with blinding retinal disease can safely stop eye injection therapy

Respiratory viruses lacking NS2 protein can be destroyed by the body's immune response

Analyzing disease severity of SARS-CoV-2 Omicron variant using RNA dependent RNA polymerase target delay

Exploring the viral dynamics of SARS-CoV-2 Omicron variant

Direct effect of SARS-CoV-2 on the kidney

Study reveals a causal link between deficiency in Parkinson’s disease gene and reduced immunoaging

Study reveals a causal link between deficiency in Parkinson’s disease gene and reduced immunoaging

UniSA scientists make a surprising discovery in the origins of antibiotic-resistant gene

An alternative mouse model of SARS-CoV-2 infection

DPP4 protein: The connection between severe COVID-19 and diabetes

Exploring the systemic infection of SARS-CoV-2 in a wild leopard in India

Researchers investigate the role of a key component of the circadian clock in heart disease

Study finds evidence to strongly implicate OAS1 as an effector gene influencing COVID-19 severity

Dexamethasone shown to upregulate innate and adaptive immune responses in COVID-19 acute respiratory distress syndrome patients

Study demonstrates that intra-host SARS-CoV-2 variants with reduced infectivity are developed during infection

Study identifies cellular receptors for alphaviruses shared across mosquitoes, humans, and animals

Researchers engineer enucleated cells to deliver therapeutics precisely to diseased tissues

Discovery opens up the possibility of pursuing new therapies for FOP

eBook: Using iPSCs models for human disease research and drug discovery eBook

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson