Gene News and Research

Latest Gene News and Research

Study reveals novel mechanism underlying infantile spasms-associated learning deficits

Researchers report that infantile spasms, a rare but serious seizure disorder in babies, appear to be the result of a molecular pathway gone awry.

3 Aug 2021

NSF awards $441,028 to address the workforce needs of regenerative medicine

Regenerative medicine is a cross-disciplinary field that aims to repair or replace abnormal organs by growing tissues in the laboratory or cells for therapy.

3 Aug 2021

Purifying selection drives time-dependency of short-term mutation rates in SARS-CoV-2 and pH1N1 influenza

A new paper, available on the medRxiv* preprint server, indicates the adaptation undergone by the SARS-CoV-2 molecular genome and the pH1N1 influenza pandemic strain during the first year of their spread, separately. Using statistical and phylogenetic skills, the researchers present a picture of the emergence, rates of change, and of growth, of these two viruses as time passes.

3 Aug 2021

Hormone-resistant prostate, breast cancers added to clinical trial of experimental DNA therapy

The Republic of Belarus Ministry of Health has approved expanding the ongoing clinical trial of CureLab Oncology's Elenagen, an experimental DNA therapy, to include two new arms: 1) hormone-resistant breast cancer; and 2) hormone-resistant metastatic prostate cancer.

3 Aug 2021

Latin American and Caribbean research contributions to tackle challenges posed by brain diseases

Every year there are nearly ten million new cases of dementia globally, of which Alzheimer's Disease (AD) is the most common form, accounting for around 60-70% of cases.

2 Aug 2021

Finding potential microRNAs from humans and plants against SARS-CoV-2

A new study focuses on the identification of probable miRNA candidates from three medicinal plants.

1 Aug 2021

UVA researchers overturn conventional wisdom on action of key hormone receptors within cells

Researchers at the University of Virginia School of Medicine have overturned conventional wisdom on the workings of vital hormone receptors within cells, a finding that could boost drug development for diabetes and related metabolic disorders, cancer and other diseases.

31 Jul 2021

UT Southwestern discovers the Achilles’ heel in ovarian cancers and potential biomarkers

UT Southwestern faculty have discovered what appears to be an Achilles' heel in ovarian cancers, as well as new biomarkers that could point to which patients are the best candidates for possible new treatments.

30 Jul 2021

Newly identified genetic mutation causes rare, early onset inflammatory bowel disease

Johns Hopkins Medicine researchers, in collaboration with national and international researchers, have identified a genetic mutation in a small number of children with a rare type of inflammatory bowel disease.

30 Jul 2021

Researchers test a library of lipid-based compounds to enable safe delivery of RNA drugs to the lungs

Hokkaido University researchers in Japan created and tested a library of lipid-based compounds to find a way to safely and effectively deliver RNA drugs to the lungs.

30 Jul 2021

New integrative NGS panel for analysis of standard and novel biomarkers in lymphoid neoplasms

Increasing knowledge about genomic biomarkers has facilitated better monitoring and personalized management of patients with B-cell malignant tumors.

29 Jul 2021

Study examines the role of programmed cell death ligands in skin immune responses

T cells are a crucial part of the human adaptive immune system. In response to a foreign invader in the body, various subsets of T cells are responsible for several functions that include killing infected cells and secreting signaling molecules called cytokines that tell other immune cells where to go and what to do.

29 Jul 2021

A quantitative assessment of SARS-CoV-2 bioaerosol production

In an effort to improve the sensitivity and sample recovery of mask sampling, researchers developed a mask sampling tool to assess bioaerosol variation.

28 Jul 2021

Removing RNA-binding protein in subtype of leukemia can help to slow the cancer's development

Removing a protein that is often overexpressed in a rare and aggressive subtype of leukemia can help to slow the cancer's development and significantly increase the likelihood of survival, according to a study in mice led by scientists at the UCLA Jonsson Comprehensive Cancer Center.

28 Jul 2021

Antibacterial immunity may change in the intestines based on circadian cycle

The body's ability to prevent food poisoning by producing a natural antimicrobial compound increases during the day, when exposure to noxious bacteria is most likely, a new study by UT Southwestern scientists suggests.

28 Jul 2021

Cats could be a valuable model organism for geneticists, expert says

Although cats have lived alongside humans for millennia, it remains a dogs' world. This bias has historically bled into science as well.

28 Jul 2021

Study: All GA-binding proteins have the highest expression levels in secondary glioblastomas

Oncotarget published "TERT and its binding protein: overexpression of GABPA/B in high grade gliomas" which reported that all GA-binding proteins progress through the glioma grades and have the highest expression levels in secondary glioblastomas.

28 Jul 2021

New insights on replication-stress sensitivity in breast cancer cells

Oncotarget published "Frame-shift mediated reduction of gain-of-function p53 R273H and deletion of the R273H C-terminus in breast cancer cells result in replication-stress sensitivity" which reported that these authors recently documented that gain-of-function mutant p53 R273H in triple negative breast cancer cells interacts with replicating DNA and PARP1.

28 Jul 2021

Oncotarget data reveals retinoic acid as fundamental regulator of cell cycle and differentiation

Oncotarget published "Role for Fgr and Numb in retinoic acid-induced differentiation and G0 arrest of non-APL AML cells" which reported that retinoic acid is a fundamental regulator of cell cycle and cell differentiation.

28 Jul 2021

Umbilical cord-derived mesenchymal stem cells show promise to treat muscular dystrophies

Results of a compassionate-use study released in STEM CELLS Translational Medicine show promising results for treating muscular dystrophies with mesenchymal stem cells (MSCs) derived from Wharton's jelly (WJ), a substance found in the umbilical cord. Led by doctors at Klara Medical Center (KMC), Czestochowa, Poland, these WJ-MSC treatments resulted in significant improvement in several body muscles in most of the patients, with no serious side effects.

27 Jul 2021

Gene News and Research

Latest Gene News and Research

Study reveals novel mechanism underlying infantile spasms-associated learning deficits

NSF awards $441,028 to address the workforce needs of regenerative medicine

Purifying selection drives time-dependency of short-term mutation rates in SARS-CoV-2 and pH1N1 influenza

Hormone-resistant prostate, breast cancers added to clinical trial of experimental DNA therapy

Latin American and Caribbean research contributions to tackle challenges posed by brain diseases

Finding potential microRNAs from humans and plants against SARS-CoV-2

UVA researchers overturn conventional wisdom on action of key hormone receptors within cells

UT Southwestern discovers the Achilles’ heel in ovarian cancers and potential biomarkers

Newly identified genetic mutation causes rare, early onset inflammatory bowel disease

Researchers test a library of lipid-based compounds to enable safe delivery of RNA drugs to the lungs

New integrative NGS panel for analysis of standard and novel biomarkers in lymphoid neoplasms

Study examines the role of programmed cell death ligands in skin immune responses

A quantitative assessment of SARS-CoV-2 bioaerosol production

Removing RNA-binding protein in subtype of leukemia can help to slow the cancer's development

Antibacterial immunity may change in the intestines based on circadian cycle

Cats could be a valuable model organism for geneticists, expert says

Study: All GA-binding proteins have the highest expression levels in secondary glioblastomas

New insights on replication-stress sensitivity in breast cancer cells

Oncotarget data reveals retinoic acid as fundamental regulator of cell cycle and differentiation

Umbilical cord-derived mesenchymal stem cells show promise to treat muscular dystrophies

Genomics - Industry Focus eBook (2nd edition) eBook

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson