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Study highlights the urgent need for combinatorial drug therapies for SARS-CoV-2

Researchers investigated the susceptibility of naturally-occurring severe acute respiratory syndrome coronavirus 2 main protease variants to protease inhibitor drugs, including nirmatrelvir and ensitrelvir.

11 Aug 2022

Assessment of replicon ribonucleic acid COVID-19 vaccine in nonhuman primates

Researchers explored the immunogenicity of a replicon ribonucleic acid (repRNA) COVID-19 vaccine, repRNA-CoV2S, in pigtail macaques.

11 Aug 2022

Study identifies multiple pathways adopted by SARS-CoV-2 to develop resistance to nirmatrelvir

Researchers demonstrated multiple routes SARS-CoV-2 might take to develop high-level resistance to nirmatrelvir, an oral antiviral targeting the 3C-like protease (3CLpro) of SARS-CoV-2.

11 Aug 2022

Crying out for new disease diagnoses

In this interview, we speak to Dr. Fei Liu and Dr. Luke P. Lee about their new iTears platform and how it could help to diagnose disease from tears.

11 Aug 2022

Gut microbial and immune parameters linked to heterogeneous inter-personal COVID-19 vaccine-triggered immunity

A new study identified the gut microbial and immune variables linked to heterogeneous messenger ribonucleic acid (mRNA) COVID-19 vaccine responses between individuals.

11 Aug 2022

SARS-CoV-2 receptor-binding domain-based protein subunit vaccine shows promise against multiple SARS-CoV-2 variants

Researchers described a novel protein subunit vaccine comprising the receptor-binding domain (RBD) of ancestral SARS-CoV-2 spike (S) protein, dimerized with an immunoglobulin (Ig)G1-fraction, crystallizable (Fc) domain.

11 Aug 2022

How did the COVID-19 pandemic impact the epidemiology of antibiotic resistant bacteria?

In an article, a mathematical model was used to explore how behavioral responses to the COVID-19 pandemic impact the anti-microbial resistance across communities.

11 Aug 2022

Azelastine nasal spray could decrease SARS-CoV-2 load

A new study illustrated that early azelastine nasal spray therapy might lower the SARS-CoV-2 load among virus-infected patients.

11 Aug 2022

Nanoparticle-based lateral flow immunoassay for the detection of anti-SARS-CoV-2 neutralizing antibodies

In a recent Biomaterials study, researchers developed AIEgen-embedded polystyrene (PS) nanoparticles-based LFIA that can accurately detect anti-SARS-CoV-2 NAb in serum samples of vaccinated individuals.

11 Aug 2022

Sniffing out cancer with insect olfactory neural circuits

A fascinating new preprint reports the results of examining the VOC composition from individual cell cultures derived from human oral cancers, using an experimental setup employing an insect brain with attached antenna.

11 Aug 2022

What is the association between polyfluoroalkyl substance exposure and risk of non-viral hepatocellular carcinoma?

The current study, published online in the journal JHEP Reports, looks at PFAS, which are endocrine disruptors and potential hepatotoxins.

11 Aug 2022

Scientists develop nanoantidote to reduce acidosis in critically ill COVID-19 patients

A group of scientists from China has recently developed an antacid nanoantidote that can effectively ameliorate blood acidosis induced by SARS-CoV-2 infection.

11 Aug 2022

Wastewater surveillance expanded to detect the presence of monkeypox

An ongoing program that monitors wastewater for the presence of SARS-CoV-2 and which has effectively predicted subsequent surges in COVID-19 cases in San Diego has been expanded to detect the presence of monkeypox.

11 Aug 2022

UIC focuses on developing an antiviral therapy for filoviruses

Researchers at the University of Illinois Chicago are working with the National Institutes of Health and researchers from across the country to establish a center for antiviral drug development for pandemic-level viruses, including Ebola and SARS-CoV-2, the virus that causes COVID-19.

11 Aug 2022

Disease/Infection News

Study highlights the urgent need for combinatorial drug therapies for SARS-CoV-2

Assessment of replicon ribonucleic acid COVID-19 vaccine in nonhuman primates

Study identifies multiple pathways adopted by SARS-CoV-2 to develop resistance to nirmatrelvir

Crying out for new disease diagnoses

Gut microbial and immune parameters linked to heterogeneous inter-personal COVID-19 vaccine-triggered immunity

SARS-CoV-2 receptor-binding domain-based protein subunit vaccine shows promise against multiple SARS-CoV-2 variants

How did the COVID-19 pandemic impact the epidemiology of antibiotic resistant bacteria?

Azelastine nasal spray could decrease SARS-CoV-2 load

Nanoparticle-based lateral flow immunoassay for the detection of anti-SARS-CoV-2 neutralizing antibodies

Sniffing out cancer with insect olfactory neural circuits

What is the association between polyfluoroalkyl substance exposure and risk of non-viral hepatocellular carcinoma?

Scientists develop nanoantidote to reduce acidosis in critically ill COVID-19 patients

Wastewater surveillance expanded to detect the presence of monkeypox

UIC focuses on developing an antiviral therapy for filoviruses

Transposable element controls the immune system to favor host survival during virus infection

How ultraprocessed foods affect gut microbiome and health

A low-energy, high FODMAP diet in prediabetes and diabetes?

Refined analysis method provides new insights into the dominance transition of Omicron sublineages

New CDC Vital Signs report: Few people diagnosed with hepatitis C receive timely treatment

Researchers describe case report of male monkeypox patient

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

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