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Markers in blood and spinal fluid, and a new imaging agent, show promise for early detection of Alzheimer's

With the continued aging of the population and the growing epidemic of Alzheimer's, early detection of the disease is crucial for risk assessment, testing new therapies, and eventual early intervention with better drugs, once they are developed. Four studies reported today at the Alzheimer's Association's 2008 International Conference on Alzheimer's Disease (ICAD 2008) in Chicago bring us closer to that goal of early detection by describing advances in biomarkers.

29 Jul 2008

Alzheimer's disease patients show improvement in trial of new drug

A new drug has been shown to improve the brain function of people with early stage Alzheimer's disease and reduce a key protein associated with the disease in the spinal fluid, in a small study published today in the journal Lancet Neurology and presented at the 2008 Alzheimer's Association International Conference on Alzheimer's Disease.

29 Jul 2008

Laboratory and mouse studies show targeted drug blocks the growth of breast cancer cells that spread to the brain

Using laboratory and mouse models of human breast cancer, researchers have found that a small molecule capable of targeting specific proteins on the surface of breast cancer cells can inhibit the growth of breast cancer cells that migrate to the brain.

29 Jul 2008

Laser therapy more effective than corticosteroids in long term treatment of diabetic macular edema

A promising new drug therapy used to treat abnormal swelling in the eye - a condition called diabetic macular edema - proved less effective than traditional laser treatments in a study funded by the National Eye Institute (NEI), part of the National Institutes of Health (NIH).

29 Jul 2008

How mixing medications can be fatal

A large-scale study of home medication consumption has highlighted the danger of mixing drugs.

29 Jul 2008

A daily 45 minute walk limits the impact of diabetes

According to scientists in the UK, by simply walking for an extra 45 minutes a day, people with diabetes can limit the impact of the disease.

29 Jul 2008

Statins reduce the risk of dementia by half

People at high risk for dementia who took cholesterol-lowering statins are half as likely to develop dementia as those who do not take statins, a new study shows.

28 Jul 2008

Most adults in U.S. will be overweight or obese by 2030

Most adults in the U.S. will be overweight or obese by 2030, with related health care spending projected to be as much as $956.9 billion, according to researchers at the Johns Hopkins Bloomberg School of Public Health, the Agency for Healthcare Research and Quality and the University of Pennsylvania School of Medicine. Their results are published in the July 2008 online issue of Obesity.

28 Jul 2008

Accelerated bone turnover remains after weight loss

When a person is losing a significant amount of weight, they expect to notice changes in their body. However, they may overlook changes happening in their bones.

28 Jul 2008

Viagra and Levitra ED drugs shown to allow more chemo to reach brain tumors

In a study using laboratory animals, researchers found that medications commonly prescribed for erectile dysfunction opened a mechanism called the blood-brain tumor barrier and increased delivery of cancer-fighting drugs to malignant brain tumors.

28 Jul 2008

Hormone deprivation therapy - used for prostate cancer - may cause recall and concentration problems

A recent review of the literature has found that hormone deprivation therapy, a commonly used treatment for prostate cancer, may have subtle adverse effects on cognition in patients--such as in the ability to recall and concentrate.

28 Jul 2008

Medical errors costing $1.5 billion annually

Potentially preventable medical errors that occur during or after surgery may cost employers nearly $1.5 billion a year, according to new estimates by HHS' Agency for Healthcare Research and Quality.

28 Jul 2008

New Alzheimer's studies show advances against different treatment targets

Two studies related to experimental Alzheimer's therapies reported positive results today at the 2008 Alzheimer's Association International Conference on Alzheimer's Disease (ICAD 2008) in Chicago.

28 Jul 2008

Oxytocin hormone plays role in social bonding and maternal behaviors

Oxytocin was originally studied as the "milk let-down factor," i.e., a hormone that was necessary for breast-feeding. However, there is increasing evidence that this hormone also plays an important role in social bonding and maternal behaviors.

28 Jul 2008

Physical fitness levels influence brain atrophy in Alzheimer's

People with early Alzheimer's disease who had better fitness ratings had less atrophy in key brain areas associated with memory, according to research reported today at the 2008 Alzheimer's Association International Conference on Alzheimer's Disease (ICAD 2008) in Chicago.

27 Jul 2008

Amyloid plaques seen with conventional MRI in animal model for first time

For the first time, scientists have captured images of brain lesions similar to those found in Alzheimer's disease using clinical-grade MRI in an animal model of the disease, according to research reported at the Alzheimer's Association's 2008 International Conference on Alzheimer's Disease (ICAD 2008), in Chicago.

27 Jul 2008

Drug Trial News

Markers in blood and spinal fluid, and a new imaging agent, show promise for early detection of Alzheimer's

Alzheimer's disease patients show improvement in trial of new drug

Laboratory and mouse studies show targeted drug blocks the growth of breast cancer cells that spread to the brain

Laser therapy more effective than corticosteroids in long term treatment of diabetic macular edema

How mixing medications can be fatal

A daily 45 minute walk limits the impact of diabetes

Statins reduce the risk of dementia by half

Most adults in U.S. will be overweight or obese by 2030

Accelerated bone turnover remains after weight loss

Viagra and Levitra ED drugs shown to allow more chemo to reach brain tumors

Hormone deprivation therapy - used for prostate cancer - may cause recall and concentration problems

Medical errors costing $1.5 billion annually

New Alzheimer's studies show advances against different treatment targets

Oxytocin hormone plays role in social bonding and maternal behaviors

Physical fitness levels influence brain atrophy in Alzheimer's

Amyloid plaques seen with conventional MRI in animal model for first time

Clinical trials to examine mushrooms' cancer-fighting properties

Lung inflammation from influenza and other infections could be turned off following new discovery

Amgen announces positive results for Denosumab postmenopausal osteoporosis trial

Chemo and radiation after surgery prolongs life for pancreatic cancer patients

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

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