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Rimonabant shows mixed results for slowing progression of coronary disease

The anti-obesity medication rimonabant showed mixed results in slowing progression of coronary artery disease in patients with abdominal obesity and pre-existing coronary disease, according to a new study in the April 2 issue of JAMA.

2 Apr 2008

Potential link found between bacteria found in the human digestive system and obesity

Obesity is more than a cosmetic concern because it increases a person's risk for developing high blood pressure, diabetes and many other serious health problems.

2 Apr 2008

Patient interventions with low-income and minorities increases colonoscopy rates

Patient interventions are necessary to achieve higher rates of colorectal cancer screening in low-income and minority patients, according to two studies in the current issue of Clinical Gastroenterology and Hepatology , the official journal of the American Gastroenterological Association (AGA) Institute.

2 Apr 2008

Illicit drug use increasingly glamorized in rap music

Rap music has gone from an art form that largely warned against the dangers of substance abuse to one that often glorifies illegal drug use, according to the first systematic social science study of the genre covering nearly two decades.

2 Apr 2008

Drug does not appear to reduce risk of heart attack or death following CABG surgery

Use of MC-1 (a naturally occurring metabolite of vitamin B6) before and for 30 days after coronary artery bypass graft surgery did not reduce the risk of heart attack or cardiovascular death, according to a JAMA study being released early online April 1 to coincide with its presentation at the annual conference of the American College of Cardiology.

2 Apr 2008

Dallas area cornea shortages could benefit from national study

Surgeons and patients from UT Southwestern Medical Center and UT Southwestern Transplant Services Center joined in a landmark study showing that corneas from older donors are as successful for transplants after five years as is tissue from younger donors, allowing possible expansion of the donor pool.

2 Apr 2008

Investigational treatment for advanced widespread emphysema

Researchers at Suburban Lung Associates and the Chicago Chest Center recently announced the start of the EASE (Exhale Airway Stents for Emphysema) Trial to explore an investigational treatment for advanced widespread emphysema.

2 Apr 2008

Chemotherapy-induced anemia increases risk of local breast cancer recurrence

Patients with breast cancer who developed anemia during chemotherapy had nearly three times the risk of local recurrence as those who did not, according to a study published in the April 1 issue of Clinical Cancer Research¸ a journal of the American Association for Cancer Research.

2 Apr 2008

Catheter repair of mitral valve improves heart size, symptoms

A catheter-mounted device that acts like a clothespin to clip together the flaps of a leaky heart valve is not only reducing the abnormal backflow of blood from the left ventricle to the left atrium, it is helping to shrink the enlarged, overworked heart and relieving symptoms of fluid overload - all without open-chest surgery.

2 Apr 2008

Tai Chi improves control of type 2 diabetes

Tai Chi exercises can improve the control of type 2 diabetes, suggests a small study, published ahead of print in the British Journal of Sports Medicine.

1 Apr 2008

Study results on novel drug-eluting stent coated with a biodegradable polymer

"Real-world" use of a novel drug-eluting stent coated with a biodegradable polymer is associated with good clinical outcomes, according to one-year data from a large international registry.

1 Apr 2008

A randomised, blinded, placebo-controlled trial in dementia patients continuing or stopping neuroleptics

Results of a randomised trial published in PLoS Medicine show no benefit in cognitive or neuropsychiatric outcomes from continuing neuroleptic drugs in patients with Alzheimer's disease.

1 Apr 2008

Lung transplants not dangerous for children with cystic fibrosis, after all

Responding to a study published in the New England Journal of Medicine, which concluded that lung transplants were harmful for children with cystic fibrosis, articles published in the latest issue of Pediatric Transplantation refute the conclusions and argue that the highly influential research was severely flawed.

1 Apr 2008

Eli Lilly starts trial of treatment of mild to moderate Alzheimer's disease

Eli Lilly and Company has announced the start of a Phase III clinical trial studying LY450139, an investigational gamma secretase inhibitor for the treatment of mild to moderate Alzheimer's disease.

1 Apr 2008

Disappointing resuts for pimecrolimus, investigational anti-restenosis drug

A new medication that researchers had hoped would reduce the risk of arterial renarrowing after stenting has turned in a disappointing performance in a multicenter clinical trial, but the multi-reservoir stent that was used to deliver the drug is still considered promising.

1 Apr 2008

Diabetics have same risk for heart attack, stroke or death from cardiovascular diseases

People with diabetes have the same high risk for heart attack or stroke or cardiovascular death as people who've already had a heart attack, researchers reported in Circulation: Journal of the American Heart Association.

1 Apr 2008

Childhood leukemia survivors struggle with long-term comorbidities

Survival rates of childhood cancers, especially leukemia, have improved greatly in the past three decades, but survivors of this disease still seem to face many health and lifestyle challenges as young adults.

1 Apr 2008

Cerebral microbleeds more common than previously thought

New research shows cerebral microbleeds, which are lesions in the brain, are more common in people over 60 than previously thought.

1 Apr 2008

Significant reductions in mortality shown using blood pressure-lowering treatment in very elderly

Lowering the blood pressure of elderly patients could cut their total mortality by a fifth and their rate of cardiovascular events by a third, according to a new study presented at the American College of Cardiology in Chicago and published simultaneously in the New England Journal of Medicine.

1 Apr 2008

New blood pressure drug Micardis (Telmisartan) good at reducing deaths from heart attacks

An international team of researchers have found that a new blood pressure medication is as effective in reducing cardiovascular death, with fewer side effects than the current treatments offered.

1 Apr 2008

Drug Trial News

Rimonabant shows mixed results for slowing progression of coronary disease

Potential link found between bacteria found in the human digestive system and obesity

Patient interventions with low-income and minorities increases colonoscopy rates

Illicit drug use increasingly glamorized in rap music

Drug does not appear to reduce risk of heart attack or death following CABG surgery

Dallas area cornea shortages could benefit from national study

Investigational treatment for advanced widespread emphysema

Chemotherapy-induced anemia increases risk of local breast cancer recurrence

Catheter repair of mitral valve improves heart size, symptoms

Tai Chi improves control of type 2 diabetes

Study results on novel drug-eluting stent coated with a biodegradable polymer

A randomised, blinded, placebo-controlled trial in dementia patients continuing or stopping neuroleptics

Lung transplants not dangerous for children with cystic fibrosis, after all

Eli Lilly starts trial of treatment of mild to moderate Alzheimer's disease

Disappointing resuts for pimecrolimus, investigational anti-restenosis drug

Diabetics have same risk for heart attack, stroke or death from cardiovascular diseases

Childhood leukemia survivors struggle with long-term comorbidities

Cerebral microbleeds more common than previously thought

Significant reductions in mortality shown using blood pressure-lowering treatment in very elderly

New blood pressure drug Micardis (Telmisartan) good at reducing deaths from heart attacks

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