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Patients at risk of adverse events within 3 months after stopping certain ACS therapy

Patients who receive the anti-platelet medication clopidogrel following an acute coronary syndrome (such as heart attack) appear to be at greater risk of a heart attack or death in the first 90 days after stopping clopidogrel treatment, according to a study in the February 6 issue of JAMA: The Journal of the American Medical Association.

7 Feb 2008

Novel small molecule therapy shows benefit for anemic patients via hydration of red blood cells

Researchers are identifying innovative therapeutics for sickle cell anemia that focus on specific factors in the disease's progression, such as the important role of hydration of the red blood cells.

7 Feb 2008

Study shows inadequate diagnostic criteria for eating disorders

A new study by Rhode Island Hospital and Brown University suggests that the DSM-IV criteria for eating disorders have limited clinical utility.

7 Feb 2008

Mayo Clinic Proceedings contributors discuss impact of donor organ allocation system

Liver transplant is a life saving treatment option for people with end-stage liver disease.

7 Feb 2008

Impact of electronic personal health record on hypertension under study

Whether patients with an electronic handle on their health are more successful at beating one of the nation's leading chronic diseases is under study.

7 Feb 2008

Cellcept immunosuppressant further linked to birth defects

A new study documents malformations seen in an infant born to a kidney transplant recipient who had taken mycophenolate mofetil (MMF), a widely used immunosuppressant available commercially as Cellcept.

7 Feb 2008

Calcium channel blockers cut risk of Parkinson's disease

People taking a widely used group of drugs known as calcium channel blockers to treat high blood pressure also appear to be cutting their risk of Parkinson's disease, according to a study published in the February 6, 2008, online issue of Neurology, the medical journal of the American Academy of Neurology.

7 Feb 2008

Microscopic imaging technique reveals rapid formation of Alzheimer's-associated plaques

The amyloid plaques found in the brains of Alzheimer's disease patients may form much more rapidly than previously expected.

7 Feb 2008

Half of patients undergoing cerebrovascular stent placement do not respond well to clopidogrel

A study by researchers at Rush University Medical Center, published in the February issue of the American Journal of Neuroradiology, finds that half of patients undergoing cerebrovascular stent placement did not respond well to clopidogrel.

7 Feb 2008

Brain disturbances in chronic pain

People with unrelenting pain don't only suffer from the non-stop sensation of throbbing pain.

7 Feb 2008

Brain study suggests way to measure, treat autism

Researchers have pinpointed subtle deficits in the brains of people with autism spectrum disorder (ASD) that they say could aid more precise diagnoses and perhaps improve treatment of ASD.

7 Feb 2008

For safety, NHLBI changes intensive blood sugar treatment strategy in trial of diabetes and cardiovascular disease

The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health has stopped one treatment within a large, ongoing North American clinical trial of diabetes and cardiovascular disease 18 months early due to safety concerns after review of available data, although the study will continue.

6 Feb 2008

Both Alpha-Hydroxy and Beta-Hydroxy acid peels promise relief for acne sufferers

Chemical peels using either alpha-hydroxy acid or beta-hydroxy acid are both highly effective in treating mild to moderately severe facial acne, researchers at the Saint Louis University School of Medicine have found - the first study to compare the two different types of acid peels as therapies for the skin disorder.

6 Feb 2008

Australian gene test opens door to personalised care

Australian researchers have led a study published in the New England Journal of Medicine that shows a simple blood test can allow doctors to predict which HIV patients will have a side effect, known as a hypersensitivity reaction, to a particular medication before it is prescribed.

6 Feb 2008

People with manic depression have a distinct chemical signature in their brains

People with manic depression have a distinct chemical signature in their brains, according to a new study. The research, published in the journal Molecular Psychiatry, may also indicate how the mood stabilisers used to treat the disorder counteract the changes in the brain that it appears to cause.

5 Feb 2008

PDAs push older adults into increasing their physical activity levels

Today's younger generation may reckon that "ne'er the twain shall meet" where technology and their elders are concerned. However, ongoing research by Abby King, PhD, professor of health research and policy and of medicine at the Stanford Prevention Research Center, appears to be gradually dispelling that notion.

5 Feb 2008

Study shows that a key protein appears to enable spread of melanoma to the small intestine

A study by researchers at the John Wayne Cancer Institute at Saint John's Health Center has shown that a receptor protein found on melanoma cells appears to facilitate the disease's spread to the small intestine.

5 Feb 2008

Experimental drug shows promise for cystic fibrosis

An experimental drug that has proven effective in treating muscular dystrophy also works for cystic fibrosis, according to researchers at the University of Alabama at Birmingham (UAB).

5 Feb 2008

Taking more than one NSAID may lead to complications

Nonsteroidal anti-inflammatory drugs (NSAIDs) are used to treat arthritis, which affects one-third of all adults.

5 Feb 2008

Study finds widespread vitamin and mineral use among cancer survivors, although benefits of such use remain unclear

Use of vitamin and mineral supplements among cancer survivors is widespread, despite inconclusive evidence that such use is beneficial, according to a comprehensive review of scientific literature conducted by researchers at Fred Hutchinson Cancer Research Center and published Feb. 1 in the Journal of Clinical Oncology.

5 Feb 2008

Drug Trial News

Patients at risk of adverse events within 3 months after stopping certain ACS therapy

Novel small molecule therapy shows benefit for anemic patients via hydration of red blood cells

Study shows inadequate diagnostic criteria for eating disorders

Mayo Clinic Proceedings contributors discuss impact of donor organ allocation system

Impact of electronic personal health record on hypertension under study

Cellcept immunosuppressant further linked to birth defects

Calcium channel blockers cut risk of Parkinson's disease

Microscopic imaging technique reveals rapid formation of Alzheimer's-associated plaques

Half of patients undergoing cerebrovascular stent placement do not respond well to clopidogrel

Brain disturbances in chronic pain

Brain study suggests way to measure, treat autism

For safety, NHLBI changes intensive blood sugar treatment strategy in trial of diabetes and cardiovascular disease

Both Alpha-Hydroxy and Beta-Hydroxy acid peels promise relief for acne sufferers

Australian gene test opens door to personalised care

People with manic depression have a distinct chemical signature in their brains

PDAs push older adults into increasing their physical activity levels

Study shows that a key protein appears to enable spread of melanoma to the small intestine

Experimental drug shows promise for cystic fibrosis

Taking more than one NSAID may lead to complications

Study finds widespread vitamin and mineral use among cancer survivors, although benefits of such use remain unclear

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