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Rapamycin and Gleevec reverses effects of portal hypertension in rats

A combined treatment with rapamycin and Gleevec might reverse the effects of portal hypertension in patients with chronic liver disease, according to the results of a new study on rats.

2 Oct 2007

Types of sleep and risk of mortality

The first study to assess the stability of three aspects of sleep behavior in relation to long-term mortality finds an increased risk of mortality in short sleep, long sleep and frequent use of medications, according to a study published in the October 1 issue of the journal SLEEP.

2 Oct 2007

Botched production of insulin molecule may lead to diabetes

Picture a pretzel factory production line, with conveyer belts carrying the dough, formed into unbaked pretzels, down to the oven to be cooked.

2 Oct 2007

Alcohol and sleep restriction can affect young men's alertness and driving performance

Combining low-dose alcohol with moderate sleep restriction can have a significant adverse effect on young men's subjective alertness and performance behind the wheel, according to a study published in the October 1 issue of the journal SLEEP.

2 Oct 2007

The role of working for pay on adolescent tobacco use

Fourteen to 18-year-old adolescents are at an increased risk to initiate smoking when they start to work, according to researchers from the Johns Hopkins Bloomberg School of Public Health.

1 Oct 2007

Best weight-loss plans for heart health

Over the past three decades, the rising obesity epidemic has been accompanied by a proliferation of weight-loss plans. However, as a new study by researchers from the University of Massachusetts Medical School (UMMS) reveals, these weight-loss plans vary significantly in their ability to positively affect heart health.

1 Oct 2007

Androgen deprivation therapy for prostate cancer may encourage spread of disease

A popular prostate cancer treatment called androgen deprivation therapy may encourage prostate cancer cells to produce a protein that makes them more likely to spread throughout the body, a new study by Johns Hopkins researchers suggests.

1 Oct 2007

Schizophrenia candidate genes affect even healthy individuals

Do gene variants that convey risk for schizophrenia affect apparently healthy individuals? Although these genes are present in every human, individuals may have different versions of these genes, called alleles.

1 Oct 2007

Inhaled ozone impairs the body's first line of defense

As policy makers debate what levels of ozone in the air are safe for humans to breathe, studies in mice are revealing that the inhaled pollutant impairs the body's first line of defense, making it more susceptible to subsequent foreign invaders, such as bacteria.

1 Oct 2007

Job stress and work environment can contribute to depression

Job stress and a lack of social support in the workplace were associated with major episodes of depression in men, according to a study led by a University of Rochester School of Medicine and Dentistry psychologist.

1 Oct 2007

Accurate prostate cancer diagnosis depends on biopsy location

The part of the prostate that is biopsied may matter more than the number of biopsy samples taken for accurately diagnosing prostate cancer, according to a study by researchers at SUNY Upstate Medical University.

1 Oct 2007

Eldely and disabled not at increased risk of physician-assisted death

Claims that vulnerable groups, such as the elderly and people with physical or mental disabilities, are at an increased risk of physician assisted death are not supported by evidence, says an expert in this week's BMJ.

29 Sep 2007

Adding ultrasound to mammography finds more cancers, but increases false positives

Adding ultrasound to mammography finds more cancers than mammography alone, but also substantially increases the number of false positives, according to first-year results from a three-year study of the two tests.

29 Sep 2007

US high school dropout rate higher than thought

University of Minnesota sociologists have found that the U.S. high school dropout rate is considerably higher than most people think -- with one in four students not graduating -- and has not improved appreciably in recent decades.

29 Sep 2007

Study shows beneficial effect of walking on the reduction in risk of bone marrow lesions in the knee

The world's most common joint disease, osteoarthritis (OA) is a major cause of disability among adults over the age of 50.

29 Sep 2007

Painful condition affecting kidney failure patients increases risk of death

A painful and debilitating condition that affects patients with kidney failure may be more common than previously believed and appears to be strongly associated with prior exposure to certain contrast agents used in imaging studies.

29 Sep 2007

About half of California adults diagnosed with high blood pressure take blood pressure-lowering drugs

About half of California adults diagnosed with high blood pressure, or hypertension, do not take medication to lower it, researchers reported today at the American Heart Association's 61st Annual Fall Conference of the Council for High Blood Pressure Research.

29 Sep 2007

Oncolytics Biotech reports positive interim results of UK phase Ia/Ib trials

Oncolytics Biotech Inc. has announced that an oral presentation covering interim results from a U.K. Phase Ia/Ib combination REOLYSIN and radiation clinical trial for patients with advanced or metastatic cancers is scheduled to be presented at the National Cancer Research Institute (NCRI) conference on October 2, 2007 in Birmingham, U.K.

29 Sep 2007

Occupational therapy helps stroke patients

Occupational therapy can improve the lives of patients who have suffered a stroke and lessen their chances of deteriorating, according to a study published on bmj.com.

29 Sep 2007

Occupational exposures in farming and industry may be linked to death from autoimmune disease

A new study examined the possible associations between occupation and the risk of dying from systemic autoimmune diseases and found that occupational exposures in farming and industry may be linked to higher death rates from these diseases.

29 Sep 2007

Drug Trial News

Rapamycin and Gleevec reverses effects of portal hypertension in rats

Types of sleep and risk of mortality

Botched production of insulin molecule may lead to diabetes

Alcohol and sleep restriction can affect young men's alertness and driving performance

The role of working for pay on adolescent tobacco use

Best weight-loss plans for heart health

Androgen deprivation therapy for prostate cancer may encourage spread of disease

Schizophrenia candidate genes affect even healthy individuals

Inhaled ozone impairs the body's first line of defense

Job stress and work environment can contribute to depression

Accurate prostate cancer diagnosis depends on biopsy location

Eldely and disabled not at increased risk of physician-assisted death

Adding ultrasound to mammography finds more cancers, but increases false positives

US high school dropout rate higher than thought

Study shows beneficial effect of walking on the reduction in risk of bone marrow lesions in the knee

Painful condition affecting kidney failure patients increases risk of death

About half of California adults diagnosed with high blood pressure take blood pressure-lowering drugs

Oncolytics Biotech reports positive interim results of UK phase Ia/Ib trials

Occupational therapy helps stroke patients

Occupational exposures in farming and industry may be linked to death from autoimmune disease

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