Drug Trial News

RSS

Framingham Heart Study 100K result published

BioMed Central has announced that 17 research articles carried out using genetic data from the Framingham Heart Study (FHS), are being published as a supplement to BMC Medical Genetics.

23 Sep 2007

AIDS Vaccine Advocacy Coalition voices disappointment in trial results for MRK-Ad5 AIDS vaccine candidate

The AIDS Vaccine Advocacy Coalition (AVAC) released the following statement from Executive Director Mitchell Warren about the announcement that vaccinations have been discontinued in the STEP Study, a test-of-concept trial of the MRK-Ad5 AIDS vaccine candidate developed by the Merck Research Laboratories.

23 Sep 2007

Study reveals the regulatory mechanism of protein kinase A

Research conducted at the University of California, San Diego (UCSD) School of Medicine has shed new light on the structure and function of one of the key proteins in all mammalian cells, protein kinase A (PKA), an enzyme which plays an essential role in memory formation, communication between nerve cells, and cardiac function.

21 Sep 2007

Diets rich in rapidly-digested carbohydrates may cause fatty liver

Diets rich in rapidly-digested carbohydrates not only expand waistlines, but may also cause fatty liver, a condition that can lead to liver failure and death, finds a new study in mice.

21 Sep 2007

Functional brain imaging shows neural circuits contributing to pedophilia

Pedophilia, the sexual attraction of adults to children, is a significant public health concern and it does not respond well to treatment.

21 Sep 2007

Process of necrosis redefined in landmark study

A new study led by investigators from the University of Pittsburgh School of Medicine demonstrates that the process of necrosis, long thought to be a chaotic, irreversible pathway to cell death, may actually be triggered as part of a regulated response to stress by a powerful protein, SRP-6, that can potentially halt necrosis in its path.

21 Sep 2007

Noninvasive prenatal testing by analyzing mother's blood

Currently, prenatal diagnosis of genetic diseases and genetic monitoring of fetal development require invasive procedures.

21 Sep 2007

Repeat courses of corticosteroids in mothers linked to increased rate of cerebral palsy among children

When pregnant women are at high risk for preterm birth, giving them a single injection of corticosteroids has been shown to reduce the baby's chances of having serious lung problems after birth.

21 Sep 2007

Cancer patients, spouses report similar emotional distress

A cancer diagnosis affects more than just the patient. A new study from researchers at the University of Michigan Comprehensive Cancer Center finds spouses report similar physical and emotional quality of life as the patient.

21 Sep 2007

Catheter angiography may be an unnecessary follow-up to CT angiography

Even in challenging cases, CT angiography (CTA) offers an accurate and rapid diagnosis for blunt trauma victims who may have aortic or great vessel injury negating the need for more invasive procedures, according to a recent study conducted by radiologists at the University of Washington and the Harborview Injury Prevention and Research Center in Seattle, WA.

21 Sep 2007

AHRQ and FDA to collaborate in ADHD study

Two U.S. Department of Health and Human Services agencies will collaborate in the most comprehensive study to date of prescription medications used to treat attention deficit hyperactivity disorder (ADHD) and the potential for increased risk of heart attack, stroke or other cardiovascular problems.

21 Sep 2007

Study looks at mitochondrial variation in sperm traits and sperm competitive ability

University of Nevada, Reno researchers Jeanne and David Zeh of the Department of Biology have received a five-year, $650,000 grant from the National Science Foundation to investigate the effects of natural mitochondrial variation on sperm traits and sperm competitive ability.

20 Sep 2007

Hydrogen sulfide limits severe heart attack damage

Administering hydrogen sulfide (H2S) directly into the heart during a simulated heart attack significantly reduces the tissue and cell damage often seen in oxygen-starved organs, according to a new study from researchers at the University of Alabama at Birmingham

20 Sep 2007

Secondhand smoke exposure could interfere with academic test performance

Teens exposed to secondhand smoke at home are at increased risk of test failure in school, suggests a new study in the Journal of Adolescent Health.

20 Sep 2007

Repeat steroids to premature infants linked to cerebral palsy

Repeated courses of a drug that is used to improve the survival of unborn premature babies also may increase the risk of cerebral palsy in those children, according to results from a multi-center study, funded by the National Institutes of Health and led by Ronald Wapner, M.D., professor of obstetrics and gynecology, Columbia University Medical Center and attending obstetrician and gynecologist at NewYork-Presbyterian Hospital/Columbia.

20 Sep 2007

Parental participation in medical decisions

The majority of parents feel they play a significant role in making medical decisions for their child, according to researchers at the University of Michigan C.S. Mott Children's Hospital.

20 Sep 2007

Humanitarian otologic missions: Long-term surgical results

Performing otologic surgery in the austere environment of a developing nation is a difficult undertaking.

20 Sep 2007

Aromatherapy massages and music relaxes nurses in accident and emergency

Nurses working in an accident and emergency department reported that their anxiety levels fell dramatically when they were given aromatherapy massages while listening to music, according to research in the September issue of the UK-based Journal of Clinical Nursing.

20 Sep 2007

DNA microarray chips improved therapy in some patients with incurable cancer

Like many oncologists, Eric P. Lester, M.D., was faced with a dilemma: seven patients with advanced, incurable cancer, an arsenal of drugs that may or may not help them, and not enough solid proof about treatment efficacy to guide him.

20 Sep 2007