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Incidents of serious adverse drug events more than double

Incidents of serious adverse drug events including deaths reported to the U.S. Food and Drug Administration (FDA) rose by more than double over a seven year period and painkillers and immune-system boosters were responsible for most.

11 Sep 2007

Oncologists critical in managing psychiatric disorders in patients with advanced cancer

Mental illness and emotional distress in patients with advanced cancer are often overlooked by oncologists but, if screened for, can be adequately managed to improve a patient's quality of life.

11 Sep 2007

Yellow plant pigments may lower risk for age-related eye disease

Consuming higher levels of the yellow plant pigments lutein and zeaxanthin may be associated with a lower risk for age-related macular degeneration, according to a report in the September issue of Archives of Ophthalmology, one of the JAMA/Archives journals.

11 Sep 2007

New approaches to transcutaneous electrical nerve stimulation studied

Current post-operative pain control methods have proved inadequate for those who have undergone total knee replacement (TKR), according to University of Iowa College of Nursing researcher.

11 Sep 2007

Mediterranean diet may help people with Alzheimer's disease live longer

A Mediterranean diet may help people with Alzheimer's disease live longer than patients who eat a more traditional Western diet.

11 Sep 2007

Mind-body therapies may help elderly chronic pain sufferers

Mind-body therapies, which focus on the interactions between the mind, body and behavior, and the ways in which emotional, mental, social and behavioral factors can affect health, may be of particular benefit to elderly chronic pain sufferers.

11 Sep 2007

HIV patients with declining platelet counts appear to be at increased risk for HIV-associated dementia

Therapies leading to longer life for HIV patients have paradoxically increased the prevalence of this condition. Identifying biological markers for the development of HIV–associated dementia is critical both for diagnosing the disorder and for understanding its underlying mechanisms.

11 Sep 2007

Chemotherapy may be culprit for fatigue in breast cancer survivors

A new study finds that, compared to healthy women, breast cancer survivors reported more days of fatigue and more severe fatigue symptoms.

11 Sep 2007

Being overweight may independently increase risk for developing coronary heart disease

Being moderately overweight or obese appears to increase the risk for developing coronary heart disease events independent of traditional cardiovascular risk factors, according to a meta-analysis of previously published studies in the September 10 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

11 Sep 2007

Antidepressant citalopram shows promise in treating symptoms of dementia

Researchers have found surprising evidence that an antidepressant (citalopram) may perform as well as a commonly-prescribed antipsychotic (risperidone) in the alleviation of severe agitation and psychotic symptoms of dementia.

11 Sep 2007

Coding and noncoding genes are involved in and cooperate in human tumorigenesis

A new study provides evidence that noncoding RNAs and interactions between noncoding genes play a much greater role in human cancer than was previously understood.

11 Sep 2007

Adverse drug events on the rise

The number of serious adverse drug events reported to the U.S. Food and Drug Administration (FDA) more than doubled between 1998 and 2005, as did deaths associated with adverse drug events, according to a report in the September 10 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

11 Sep 2007

Two drugs equally effective for heart patients undergoing angioplasty

In lifesaving procedures to open blocked heart arteries a key question has persisted for years: Is use of the more expensive drug, abciximab, justified over use of the less-expensive eptifibatide

11 Sep 2007

Congestive heart failure is rare among leukemia patients who take imatinib

Congestive heart failure rarely occurs among leukemia patients who take imatinib, researchers at The University of Texas M. D. Anderson Cancer Center found after an exhaustive review of the detailed medical histories of 1,276 patients who enrolled in clinical trials for the drug.

10 Sep 2007

Scientists shed new light on how antibodies fight HIV

By furthering scientists' understanding of the molecular mechanisms that separate the minority of successful HIV antibodies from the majority of ineffective antibodies, the work may have implications for future attempts to design an HIV vaccine.

10 Sep 2007

Schizophrenia-linked gene keeps new adult brain cells under control

The study reveals that the gene, known as Disrupted-In-Schizophrenia 1 (DISC1), directs the incorporation of new neurons into the adult brain and keeps the process under control. The gene's newly discovered roles might help to explain why schizophrenia's symptoms generally arise in adolescence or early adulthood, the researchers suggested.

10 Sep 2007

Prevention of primary variceal bleeding

Beta blockers should be the first line of prevention against variceal bleeding in patients with cirrhosis and portal hypertension. While banding is similarly effective in reducing the incidence of such bleeding, it can have fatal complications and is more expensive.

10 Sep 2007

Nuclear medicine approach can be first choice for excluding pulmonary embolism in young women

Young women at risk of having a pulmonary embolism - a potential life-threatening blockage in a lung artery - should first undergo a ventilation/perfusion lung scan (V/Q scan) rather than a CT (computed tomography) angiogram, conclude authors in a paper published in the September Journal of Nuclear Medicine.

10 Sep 2007

Virochip technique identifies new viruses in study of respiratory infections and asthma attacks

A new study has found an unexpected number of viruses and viral subtypes in patients with respiratory tract infections (RTIs). The technique used in the study may help identify new viruses associated with human diseases.

10 Sep 2007

New understanding of role of schizophrenia risk gene DISC1 in normal adult brains

How the gene that has been pegged as a major risk factor for schizophrenia and other mood disorders that affect millions of Americans contributes to these diseases remains unclear.

10 Sep 2007

Drug Trial News

Incidents of serious adverse drug events more than double

Oncologists critical in managing psychiatric disorders in patients with advanced cancer

Yellow plant pigments may lower risk for age-related eye disease

New approaches to transcutaneous electrical nerve stimulation studied

Mediterranean diet may help people with Alzheimer's disease live longer

Mind-body therapies may help elderly chronic pain sufferers

HIV patients with declining platelet counts appear to be at increased risk for HIV-associated dementia

Chemotherapy may be culprit for fatigue in breast cancer survivors

Being overweight may independently increase risk for developing coronary heart disease

Antidepressant citalopram shows promise in treating symptoms of dementia

Coding and noncoding genes are involved in and cooperate in human tumorigenesis

Adverse drug events on the rise

Two drugs equally effective for heart patients undergoing angioplasty

Congestive heart failure is rare among leukemia patients who take imatinib

Scientists shed new light on how antibodies fight HIV

Schizophrenia-linked gene keeps new adult brain cells under control

Prevention of primary variceal bleeding

Nuclear medicine approach can be first choice for excluding pulmonary embolism in young women

Virochip technique identifies new viruses in study of respiratory infections and asthma attacks

New understanding of role of schizophrenia risk gene DISC1 in normal adult brains

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