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Immunotherapy before and after surgery boost longer event-free survival in head and neck cancer

Patients with locally advanced head and neck cancer who received the immune checkpoint inhibitor pembrolizumab before, during and after standard-of-care surgery had longer event-free survival without the cancer coming back and higher rates of substantial tumor shrinkage prior to surgery, according to the first interim analysis of a randomized, open-label phase 3 clinical trial led by investigators from Dana-Farber Brigham Cancer Center and Washington University School of Medicine in St. Louis.

6 May 2025

Emotional and ethical factors influence a person's decision to know Alzheimer’s risk

As researchers make progress in understanding how Alzheimer's disease develops, there are growing opportunities for healthy research participants to learn their risk of developing Alzheimer's disease dementia in the future.

6 May 2025

Cardiovascular mortality higher in women with rheumatoid arthritis and lupus

Women with the autoimmune diseases rheumatoid arthritis, lupus or systemic sclerosis may have a higher rate of death related to cardiovascular disease than men with the autoimmune diseases, according to new research published in the American Heart Association's journal Circulation: Cardiovascular Quality and Outcomes.

6 May 2025

Low blood sugar linked to retinal damage in diabetic eye disease

In a new National Institutes of Health-funded study led by scientists at the Wilmer Eye Institute, Johns Hopkins Medicine researchers say they have determined that low blood sugar, or hypoglycemia, may promote a breakdown of the blood-retinal barrier, an important boundary that regulates the flow of nutrients, waste and water in and out of the retina.

6 May 2025

ADIS project to focus on early detection and prevention of Alzheimer's disease

How can Alzheimer's disease be detected earlier? What prevention strategies are currently available, and where is research heading? These questions will take center stage at the final symposium of the ADIS project, which will take place on June 25 and 26 at Fraunhofer SCAI in Schloss Birlinghoven.

6 May 2025

Low testosterone linked to higher kidney stone risk in men, study finds

A large cross-sectional study in South Korea found that men with low testosterone levels (below 3.33 ng/mL) were significantly more likely to have kidney stones. This association held even after adjusting for age and metabolic risk factors, suggesting testosterone may play a protective role.

6 May 2025

Varicose veins increase your risk of dementia, study finds

A nationwide Korean study finds a surprising link between varicose veins and dementia, and suggests that treating the veins could help prevent vascular brain damage.

6 May 2025

Social media hurts teens with anxiety and depression more than healthy peers

Adolescents with mental health conditions spend more time on social media and engage differently online than their mentally healthy peers, particularly in social comparison and emotional reactivity to feedback. These differences vary by condition type, with internalizing disorders showing stronger effects across key engagement measures.

6 May 2025

Rethinking the social side of problem drinking

When picturing a "typical" alcoholic, people tend to imagine a person drinking at home alone. But that focus overlooks the social origins of many serious alcohol problems, say the authors of a new review paper in the journal Current Directions in Psychological Science.

6 May 2025

Shingles vaccine linked to lower risk of heart disease

People who are given a vaccine for shingles have a 23% lower risk of cardiovascular events, including stroke, heart failure, and coronary heart disease, according to a study of more than a million people published in the European Heart Journal today (Tuesday).

5 May 2025

Study reveals opposing roles of two proteins in Huntington's disease

A decade ago, University at Buffalo researchers shed some light on an enduring neuroscience mystery: How exactly does a mutated huntingtin protein (HTT) cause Huntington's disease?

5 May 2025

Gene deletion in wheat lowers allergenic proteins while maintaining bread quality

Wheat is a major source of calories, carbohydrates and protein worldwide, and its distinctive gluten proteins are what gives bread and pasta dough texture and elasticity.

5 May 2025

MED13L Foundation funds groundbreaking study at Boston Children's Hospital

The MED13L Foundation today announced a nearly $250,000 grant to help launch an innovative natural history study at Boston Children's Hospital's Rosamund Stone Zander Translational Neuroscience Center (RSZ TNC).

5 May 2025

Ultra-processed foods increase risk of anxiety and depression, study shows

A large UK Biobank study linked ultra-processed food (UPF) consumption to increased risks of anxiety, depression, substance use disorder, and other mental health outcomes. A metabolomic signature associated with UPF intake partially mediated these relationships, especially in adults under 60.

5 May 2025

Combining vagus nerve stimulation with therapy provides lasting PTSD relief

In a first-of-its-kind clinical study, scientists at The University of Texas at Dallas and Baylor University Medical Center showed that patients with treatment-resistant PTSD were symptom-free up to six months after completing traditional therapy paired with vagus nerve stimulation (VNS).

5 May 2025

Study: Kissing after a gluten-filled snack is safe for people with celiac disease

People with celiac disease have reported anxiety about ingesting gluten through a kiss, but a new study concludes that they can indulge without worry - even if their partner just had a gluten-filled snack, according to a study to be presented today at Digestive Disease Week 2025.

5 May 2025

Breakthrough brain training shows promise for Long COVID recovery

Researchers at the University of Alabama at Birmingham (UAB) have identified what is believed to be the first intervention found in a randomized controlled trial to show large and very large improvements in multiple symptoms associated with Long COVID, and to result in people debilitated by those symptoms returning to work.

5 May 2025

Women face higher depression risk from unhealthy food

A cross-sectional study of over 15,000 adults across multiple countries found that ultra-processed food (UPF) consumption was linked to higher odds of depression, especially in women across all age groups. Healthy dietary patterns were protective in women aged 18–54, but showed no benefit for men.

5 May 2025

UVA findings hold promise for developing targeted treatments for Long COVID lung complications

Groundbreaking research from the University of Virginia School of Medicine has revealed crucial new insights into the immune systems of COVID-19 survivors, particularly those struggling with persistent breathing issues.

5 May 2025

TM6SF2 gut-specific knockout aggravates liver lipid accumulation in MASLD mice

Metabolic dysfunction-associated steatotic liver disease (MASLD), is the most common form of chronic liver disease worldwide. This study aimed to explore the role of TM6SF2 in high-fat diet (HFD)-induced MASLD through the gut-liver axis.

5 May 2025