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CKMT2 regulates mitochondrial function and energy metabolism in type 2 diabetes

Creatine kinase M2 (CKMT2) plays a key role in mitochondrial dysfunction in type 2 diabetes, affecting energy metabolism in skeletal muscle.

10 Oct 2024

AI-driven oculomics assesses HbA1c for cardiovascular risk

Study demonstrates the potential of using artificial intelligence in oculomics to assess HbA1c levels from fundus images. By analyzing over 6,000 images, the researchers found that diverse datasets are key to minimizing bias and improving model reliability across different populations.

10 Oct 2024

Researchers decode how the brain identifies and responds to odors

Investigating neuronal activity in the brain, this study highlights how olfactory cues are processed, emphasizing the roles of the piriform cortex and amygdala.

10 Oct 2024

New study reveals long-term brainstem damage in COVID-19 survivors using advanced MRI scans

A study using 7T QSM identifies microstructural changes in the brainstem of COVID-19 survivors, suggesting links to long-term neuroinflammatory responses.

10 Oct 2024

Grant supports gene-editing research for rare metabolic diseases

A $14M grant will fund research on gene-editing therapies for rare metabolic diseases at the Perelman School of Medicine at the University of Pennsylvania (Penn) and Children's Hospital of Philadelphia (CHOP).

10 Oct 2024

Study explores link between muscle strength and mental health in older adults

The Granada Biosanitary Research Institute (ibs.GRANADA) and the University of Granada, in collaboration with the Biomedical Research Institute of Malaga and Platform in Nanomedicine (IBIMA Plataforma BIONAND), have carried out a study that analyses the relationship between muscle strength and mental health in cognitively healthy older adults.

10 Oct 2024

Three common cardiovascular diseases linked to cognitive impairment and dementia risk

Three common cardiovascular diseases in adults - heart failure, atrial fibrillation and coronary heart disease - are linked to cognitive impairment and increased risk of dementia, according to "Cardiac Contributions to Brain Health," a new scientific statement from the American Heart Association published today in the Association's journal, Stroke.

10 Oct 2024

Fluorescein angiography improves diagnostic accuracy in carpal tunnel surgery

In modern office life, avoiding the onset of carpal tunnel syndrome might be a daily struggle. The worst case could mean needing surgery to alleviate compression of the nerves or to repair damaged nerves.

10 Oct 2024

Neuroimaging study reveals structural brain differences in children with autism

There is new evidence that the cells responsible for communication in the brain may be structured differently in children with autism. Researchers at the Del Monte Institute for Neuroscience at the University of Rochester discovered that in some areas of the brain neuron density varies in children with autism when compared to the general population.

10 Oct 2024

The role of geroscience in understanding Alzheimer’s Disease

For more than 30 years, researchers have identified and quantified genetic and lifestyle factors for Alzheimer's Disease (AD) and other dementias. Despite extensive research, the fundamental mechanisms behind these neurodegenerative diseases are still not fully understood, and effective management of AD is taking longer than expected.

10 Oct 2024

Could heparin offer new hope in the fight against dementia?

Heparin therapy delays Alzheimer's diagnosis by one to two years, offering potential insights into new protective treatments. Large-scale health records show a promising association between the anticoagulant and delayed dementia onset.

10 Oct 2024

Breast cancer mortality plummets by 44%, but alarming racial gaps persist

The latest American Cancer Society report reveals a 44% decline in breast cancer mortality since 1989, but racial disparities remain, with underserved populations seeing little progress. Increased screening and access to treatment are critical for future reductions.

9 Oct 2024

Pitt researchers validate comprehensive blood test for Alzheimer's biomarkers

University of Pittsburgh scientists independently validated a new blood test platform that can simultaneously measure more than a hundred biomarkers of Alzheimer's disease.

9 Oct 2024

CRISPR-based rapid molecular diagnostic developed for two forms of leukemia

Researchers at Dana-Farber Cancer Institute have created a CRISPR-based rapid molecular diagnostic for two forms of leukemia that are driven by mutations that involve gene fusions.

9 Oct 2024

Study illuminates the origin and progression of bladder cancer

How bladder cancer originates and progresses has been illuminated as never before in a study led by researchers at Weill Cornell Medicine and the New York Genome Center.

9 Oct 2024

Dual immunotherapy plus chemotherapy shows promise for specific lung cancer patients

Researchers from The University of Texas MD Anderson Cancer Center have demonstrated that patients with metastatic non-squamous non-small cell lung cancer (NSCLC) harboring specific mutations in the STK11 and/or KEAP1 tumor suppressor genes were more likely to benefit from adding the immunotherapy tremelimumab to a combination of durvalumab plus chemotherapy to overcome treatment resistance typically seen in this patient population.

9 Oct 2024

New review explores Zika virus as a potential treatment for brain cancer

A new review was published in Oncotarget's Volume 15 on September 30, 2024, entitled, "Zika virus and brain cancer: Can Zika be an effective treatment for brain cancer? A systematic review."

9 Oct 2024

Novel gene therapy holds potential in treating patients with epilepsy

Researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine) are working on a therapy that holds potential in treating patients with epilepsy, a neurological disorder defined by recurring seizures due to abnormal brain activity.

9 Oct 2024

Heavy alcohol consumption associated with increased risk of cardiac arrhythmias

Researchers at LMU University Hospital find cardiac arrhythmias in partygoers who had drunk a lot of alcohol.

9 Oct 2024

Transposable elements found to be dysregulated in Alzheimer's brains, revealing potential targets for therapy

Study reveals widespread dysregulation of transposable elements (TEs) in aging human brains with Alzheimer's disease, using advanced techniques like CRISPR interference to identify TE-related risk genes.

9 Oct 2024