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Researchers reveal basis for hereditary coproporphyria

A research team led by scientists at The University of Texas Medical School at Houston has determined the structure of an enzyme that when defective causes an inherited disease that afflicts sufferers with severe abdominal pain, psychiatric symptoms, skin fragility, and light sensitivity.

9 Oct 2005

Researchers find CCL5 protein produced in the course of respiratory viral infections can serve to protect macrophages from an untimely death

Enlisted to help fight viral infections, immune cells called macrophages consume virus-infected cells to stop the spread of the disease in the body.

9 Oct 2005

Mitochondria and apoptosis research

The story of how mitochondria are recruited during times of stress to choreograph apoptosis--the cell's dance of death--is a story that fails to tell which particular set of steps the cells use most often, according to investigators at St. Jude Children's Research Hospital and the La Jolla Institute of Allergy and Immunology (San Diego, CA).

9 Oct 2005

Obese Zucker rat model shares the symptoms of obesity with a growing number of Americans

A mutant rat that mimics a 400-pound human is helping scientists understand early vascular changes that make walking a pain for more than 2 million Americans.

9 Oct 2005

Discovery provides an understanding of the mechanisms of oocyte death and a way to identify potential clinical treatments for infertility

An immature egg's internal nutrient supply is critical to its survival, an insight that offers a new route to understanding and treating infertility due to egg death, according to Duke University Medical Center researchers.

9 Oct 2005

Employment gap may be due, in part, to the "poverty trap"

Between 2003 and 2004 the employment gap widened between the number of working-age Americans with disabilities who are employed and those workers without disabilities, a new report on Capitol Hill shows.

9 Oct 2005

Patients in level I trauma centers were nearly 20 percent less likely to die than those in level II centers

Patients who are taken to a level 2 trauma center after suffering serious injury are significantly more likely to die than comparable patients treated at a major level 1 trauma center, according to researchers at the Keck School of Medicine of the University of Southern California.

9 Oct 2005

SUVs should carry health warnings

Sports utility vehicles (SUVs) should carry health warnings to raise awareness of the increased risk to pedestrians compared with ordinary cars, argue researchers in this week's British Medical Journal.

9 Oct 2005

Site in the brain that controls language in right-handed people shifts with aging

...a discovery that might offer hope in the treatment of speech problems resulting from traumatic brain injury or stroke.

9 Oct 2005

Specific gene on chromosome 15 regulates inflammation

A team of international researchers has discovered that a specific gene on chromosome 15 regulates inflammation, a finding with implications for a wide range of disorders, including cancer, cardiovascular disease, diabetes, obesity, Alzheimer's, and infections. The findings are published in the October 9 online issue of Nature Genetics.

9 Oct 2005

Osmolyte findings could have implications for the study of Alzheimer's disease, cystic fibrosis, kidney disease

Researchers at the University of Texas Medical Branch at Galveston (UTMB) have developed a new way to predict the ability of certain small molecules to protect proteins in the cells of a wide variety of organisms living in extreme environments.

9 Oct 2005

Gene variation may play fundamental role in the development and spread of cancer in the body

New research shows that a small gene variation that increases the risk of inherited cancer can also arise during the development of spontaneous, or non-inherited, tumors.

9 Oct 2005

RPL26 and nucleolin play critical roles in controlling the production of p53

Investigators at St. Jude Children's Research Hospital have discovered a previously unrecognized mechanism that controls a key protein linked to the cell's response to stress - a finding that holds promise for new ways to enhance cancer therapies or protect cells from dying after exposure to damaging chemicals or radiation.

9 Oct 2005

New data demonstrates how CA4P has anti-tumor and anti-angiogenic activity

Anti-angiogenic agents have been successful in the clinic for blocking the growth of solid tumors. However, these agents used in combination with chemotherapy have improved the survival of patients with cancers by only several months.

9 Oct 2005

Gut antibody could prove to be a promising drug target for Crohn's disease

A collaboration led by the Burnham Institute for Medical Research has found that an antibody which binds to an unusual sugar molecule residing in the gut halts the inflammation seen in Crohn's disease and other intestinal inflammations. The antibody could prove to be a promising drug target for these common chronic intestinal disorders.

9 Oct 2005

New information regarding the genetic, cellular and neurological bases of susceptibility to autism and schizophrenia

Two New Jersey research teams are reporting discoveries about the biological nature of psychiatric disorders that may bring them closer to the ultimate goal of finding cures for complex diseases, such as autism and schizophrenia.

9 Oct 2005

Novel methodology that can be used to investigate choice and introspection

When evaluating facial attractiveness, participants may fail to notice a radical change to the outcome of their choice, according to a study by researchers at Lund University, Sweden, and New York University. Equally surprising, the study shows that participants may produce confabulatory reports when asked to describe the reasons behind their choices.

9 Oct 2005

Deadly 1918 Spanish flue virus has been reconstructed and characterized

This research, reported in this week's issue of Science, is part of a larger research initiative being led by Adolfo Garcia-Sastre, PhD, Professor of Microbiology and Peter Palese, PhD, Professor and Chairman of Microbiology at Mount Sinai School of Medicine.

5 Oct 2005

Fruits and vegetables can increase or decrease the activity and toxicity of orally-administered drugs

Eating fruits and vegetables is essential to living a long and healthy life, yet research has shown they can cause dangerous interactions with medicines.

5 Oct 2005

Particular versions of the TGFb1 gene are largely responsible for how badly the illness affects patients' lungs

Subtle differences in other genes -- besides the defective gene known to cause the illness cystic fibrosis -- can significantly modify the inherited disease's severity, a large new multi-center national study has concluded.

5 Oct 2005

Medical Research News

Researchers reveal basis for hereditary coproporphyria

Researchers find CCL5 protein produced in the course of respiratory viral infections can serve to protect macrophages from an untimely death

Mitochondria and apoptosis research

Obese Zucker rat model shares the symptoms of obesity with a growing number of Americans

Discovery provides an understanding of the mechanisms of oocyte death and a way to identify potential clinical treatments for infertility

Employment gap may be due, in part, to the "poverty trap"

Patients in level I trauma centers were nearly 20 percent less likely to die than those in level II centers

SUVs should carry health warnings

Site in the brain that controls language in right-handed people shifts with aging

Specific gene on chromosome 15 regulates inflammation

Osmolyte findings could have implications for the study of Alzheimer's disease, cystic fibrosis, kidney disease

Gene variation may play fundamental role in the development and spread of cancer in the body

RPL26 and nucleolin play critical roles in controlling the production of p53

New data demonstrates how CA4P has anti-tumor and anti-angiogenic activity

Gut antibody could prove to be a promising drug target for Crohn's disease

New information regarding the genetic, cellular and neurological bases of susceptibility to autism and schizophrenia

Novel methodology that can be used to investigate choice and introspection

Deadly 1918 Spanish flue virus has been reconstructed and characterized

Fruits and vegetables can increase or decrease the activity and toxicity of orally-administered drugs

Particular versions of the TGFb1 gene are largely responsible for how badly the illness affects patients' lungs

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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