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Anticonvulsants found to be ineffective for low back pain and can have adverse effects

Anticonvulsant drugs are increasingly being used to treat low back pain, but a new study in CMAJ finds they are ineffective and can have adverse effects.

3 Jul 2018

Low-dose aspirin may reduce amyloid plaques in the brain, study shows

A regimen of low-dose aspirin potentially may reduce plaques in the brain, which will reduce Alzheimer's disease pathology and protect memory, according to neurological researchers at Rush University Medical Center, who published the results of their study today in the July issue of The Journal of Neuroscience.

2 Jul 2018

Established lung fibrosis can be reversed using diabetes drug treatment

Researchers at the University of Alabama at Birmingham have shown - for the first time - that established lung fibrosis can be reversed using a drug treatment that targets cell metabolism.

2 Jul 2018

Antioxidants do not improve sperm quality in infertile men, finds study

A large clinical trial has shown that daily antioxidant supplementation among men with infertility does not make a difference to the quality of their sperm.

2 Jul 2018

U.S. researchers recommend development of anti-cancer drugs based on mechanism of Namodenoson

Can-Fite BioPharma Ltd., a biotechnology company advancing a pipeline of proprietary small molecule drugs that address cancer, liver and inflammatory diseases, today announced that U.S. researchers published scientific findings recommending development of anti-Liver Cancer Drugs based on a mechanism of action utilized by Namodenoson.

2 Jul 2018

Despite the future uncertainty of Brexit, pharmaceutical industry continues to invest in UK R&D

Data published today by the ABPI shows that the pharmaceutical industry continues to invest significantly in UK research and development despite the future uncertainty of Brexit – working closely with healthcare professionals and organisations to improve patient care.

2 Jul 2018

Simple DNA test can predict risk of bad side effects to thiopurine drugs

Screening a tiny section of DNA could help East Asian patients avoid severe reactions to some medications.

2 Jul 2018

Ocular Therapeutix resubmits NDA for DEXTENZA

Ocular Therapeutix™, Inc., a biopharmaceutical company focused on the formulation, development, and commercialization of innovative therapies for diseases and conditions of the eye, has announced the resubmission of the Company's New Drug Application to the U.S. Food and Drug Administration for its lead product candidate DEXTENZA™ 0.4mg, for the treatment of ocular pain following ophthalmic surgery.

30 Jun 2018

Study finds that several existing anti-cancer drugs may work in part by binding to RNA

Bolstering the notion that RNA should be considered an important drug-discovery target, scientists at Scripps Research have found that several existing, FDA-approved anti-cancer drugs may work, in part, by binding tightly to RNA, the regulators of the basic activities of life within cells.

30 Jun 2018

Newer anticoagulant may be safer for dialysis patients with Afib

People with irregular heartbeat due to a condition called atrial fibrillation, are often prescribed blood thinners to reduce the risk of blood clots that can cause a stroke.

30 Jun 2018

New therapeutic may help drug addicts avoid future drug use

A new therapeutic may help reverse chemical imbalances made to the brain by habitual drug use and could one day help recovering drug addicts avoid future drug use.

30 Jun 2018

Researchers focus on delivery of insulin in pill form

One mother vividly remembers her three-and-a-half-year-old son's pleas when he received insulin injections several times each day. "He would beg and plead, 'Don't do it Momma!'" she recalls.

29 Jun 2018

Blood pressure medications linked to increased mortality, memory problems in old and frail patients

Old and frail patients have an increased mortality risk and increased memory problems when their blood pressure is lowered too much through medication.

28 Jun 2018

LUMICKS partners with AstraZeneca, University of Cambridge to establish new 'Center of Excellence for Dynamic Single-Molecule Analysis for Accelerated Drug Discovery and Biology'

The center will be based around LUMICKS’ C-Trap™ optical tweezers–fluorescence microscope, which for the first time enables real-time observation and probing of biomolecular interactions. The approach will be pioneered in several pharmacology and biology assays with the aim of accelerating the discovery of potential new drugs.

From Lumicks 28 Jun 2018

Researchers examine whether taking a hallucinogen can curb cocaine use

Unlike with alcohol or nicotine, there is not a pharmacological option available to individuals addicted to cocaine to help them stop using the drug. However, researchers at the University of Alabama at Birmingham believe the tool to help individuals treat their addiction may very well exist.

28 Jun 2018

New heat stable version of Carbetocin to prevent hemorrhage after birth

The World Health Organization (WHO) has said that a new heat stable version of a drug Carbetocin can save lives of new mothers could “revolutionize” therapy. The results of the study looking at the effectiveness of the new version of the drug were published in the latest issue of the New England Journal of Medicine.

28 Jun 2018

FDA approves cannabis based drug for severe form of epilepsy

The U.S. Food and Drug Administration (FDA) on the 25th of June 2018 approved Epidiolex oral solution that is essentially cannabidiol or the active component of marijuana or cannabis. As of now the drug is approved for use in two rare forms of epilepsy - Lennox-Gastaut syndrome and Dravet syndrome. The approval comes for individuals over two years of age.

28 Jun 2018

Antidepressant drug appears to effectively stop progression of PBC

Gail Wright considered herself healthy. She had no idea she had a chronic liver disease. "I was at a routine check-up and my doctor said my liver enzymes were elevated. I was sent to a specialist but I wasn't too worried. I didn't have any symptoms."

27 Jun 2018

Human insulin as safe and effective as expensive insulin analogs for patients with type 2 diabetes

Patients with Type 2 diabetes who were treated with the newer generation of insulin analog drugs did not have substantially better outcomes than those treated with less costly human insulin, according to a study by Yale School of Medicine researchers and colleagues at Kaiser Permanente.

27 Jun 2018

New avenue for cancer treatment opens when one drug fails

A new class of cancer drugs – called CDK4/6 inhibitors -- recently approved to treat breast cancer can stunt the cancer's growth and replication.

27 Jun 2018

Pharmaceutical News

Anticonvulsants found to be ineffective for low back pain and can have adverse effects

Low-dose aspirin may reduce amyloid plaques in the brain, study shows

Established lung fibrosis can be reversed using diabetes drug treatment

Antioxidants do not improve sperm quality in infertile men, finds study

U.S. researchers recommend development of anti-cancer drugs based on mechanism of Namodenoson

Despite the future uncertainty of Brexit, pharmaceutical industry continues to invest in UK R&D

Simple DNA test can predict risk of bad side effects to thiopurine drugs

Ocular Therapeutix resubmits NDA for DEXTENZA

Study finds that several existing anti-cancer drugs may work in part by binding to RNA

Newer anticoagulant may be safer for dialysis patients with Afib

New therapeutic may help drug addicts avoid future drug use

Researchers focus on delivery of insulin in pill form

Blood pressure medications linked to increased mortality, memory problems in old and frail patients

LUMICKS partners with AstraZeneca, University of Cambridge to establish new 'Center of Excellence for Dynamic Single-Molecule Analysis for Accelerated Drug Discovery and Biology'

Researchers examine whether taking a hallucinogen can curb cocaine use

New heat stable version of Carbetocin to prevent hemorrhage after birth

FDA approves cannabis based drug for severe form of epilepsy

Antidepressant drug appears to effectively stop progression of PBC

Human insulin as safe and effective as expensive insulin analogs for patients with type 2 diabetes

New avenue for cancer treatment opens when one drug fails

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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