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Omissions on death certificates lead to undercounting of opioid overdoses

In a refrigerator in the coroner’s office in Marion County, Ind., rows of vials await testing. They contain blood, urine and vitreous, the fluid collected from inside a human eye.

29 Mar 2018

Enclosed point-of-use filter enhances quality of API for kidney dialysis

Amazon Filters reports a leading pharmaceutical company is using SupaPore PPG pleated depth filter cartridges to enable them to achieve a safe, enclosed point-of-use filter on their nitrogen gas distribution line used in the production of an Active Pharmaceutical Ingredient (API) for kidney dialysis treatments.

From Amazon Filters Ltd. 29 Mar 2018

Study uncovers more complex, elaborate role for the body’s macromolecular complexes

Scientists at the National Institute on Drug Abuse Intramural Research Program have uncovered evidence that shows a more complex and elaborate role for the body's hard-working G protein-coupled receptors than previously thought, suggesting a conceptual advance in the fields of biochemistry and pharmacology.

28 Mar 2018

New long-acting delivery system has potential to lessen side effects from NRTIs

An HIV diagnosis, while no longer constituting a death sentence, brings with it a lifetime, daily regimen of medication to help continually combat the virus.

27 Mar 2018

FDA-approved inhibitors could be repurposed to target ARID1A-mutant ovarian cancers

Wistar researchers have found rationale for repurposing a class of antitumor compounds called HDAC inhibitors, already approved by the FDA for the treatment of diseases such as leukemia, as a new therapeutic option for ovarian cancer with mutations in the ARID1A gene.

27 Mar 2018

LSTM researchers show potential of novel antiparasitic drug to combat malaria

Researchers from the Liverpool School of Tropical Medicine have shown the large potential impact of a completely new type of antimalarial drug that kills mosquitoes, as opposed to existing drugs that target the parasite, to reduce the spread of malaria.

27 Mar 2018

Antibiotic use linked to higher risk of severe viral disease in mice

People infected with West Nile virus can show a wide range of disease. Some develop life-threatening brain infections. Others show no signs of infection at all. One reason for the different outcomes may lie in the community of microbes that populate their intestinal tracts.

27 Mar 2018

Cell-penetrating 'nanodrills' could be new platform for intracellular drug delivery

Researchers at Oregon State University and Oregon Health & Science University have created new nanomaterials able to cross cell membranes, establishing a novel platform for the intracellular delivery of molecular drugs and other cargo.

27 Mar 2018

Magnesium found to be effective for mild-to-moderate depression symptoms

Magnesium is effective for mild-to-moderate depression in adults, research has found.

From BetterYou Ltd 27 Mar 2018

MSU scientists test promising drug to prevent cancer in high-risk patients

Michigan State University scientists are testing a promising drug that may stop a gene associated with obesity from triggering breast and lung cancer, as well as prevent these cancers from growing.

27 Mar 2018

New research does not support previous findings that antidepressants impact breastfeeding

New research does not support the previously observed negative impacts of antidepressant use on breastfeeding. In the British Journal of Clinical Pharmacology study, use of serotonin reuptake inhibitors in late pregnancy was not linked with an increased risk of women experiencing low milk supply.

26 Mar 2018

Frequent and public opioid users may be best candidates for naloxone training

In response to America's opioid crisis, public health departments and community organizations across the country have started to train opioid users to reverse overdoses in other users with the opioid-blocker naloxone.

26 Mar 2018

SLU researchers turn off excruciating chemo pain in animal model

In a recent paper published in the journal Pain, Saint Louis University researchers describe their success in an animal model in turning off the excruciating pain that often accompanies a colorectal cancer drug.

26 Mar 2018

Daily regimen of ibuprofen can ward off Alzheimer's disease, say neuroscientists

A Vancouver-based research team led by Canada's most cited neuroscientist, Dr. Patrick McGeer, has successfully carried out studies suggesting that, if started early enough, a daily regimen of the non-prescription NSAID (nonsteroidal anti-inflammatory drug) ibuprofen can prevent the onset of Alzheimer's disease.

26 Mar 2018

Initiating opioid analgesic decreases use of antipsychotics, benzodiazepines in Alzheimer's patients

Initiating an opioid analgesic reduced the use of antipsychotics and benzodiazepines in persons with Alzheimer's disease, a recent study from the University of Eastern Finland shows.

26 Mar 2018

New University of Bath project seeks to make injections safer

Due to the complicated nature of preparing injections, mistakes are made in around a third of doses. Although these are often minor errors, it is a statistic that University of Bath pharmacist Dr Matthew Jones wants to change with a new project to improve patient safety.

23 Mar 2018

New survey aims to identify opioid prescription patterns by oral and maxillofacial surgeons

At the 47th Annual Meeting of the American Association for Dental Research, held in conjunction with the 42nd Annual Meeting of the Canadian Association for Dental Research, Brandon Michael Syme, University of Iowa College of Dentistry, Iowa City, presented a poster titled "Opioid Prescribing Patterns of Oral and Maxillofacial Surgeons: A Nationwide Survey."

23 Mar 2018

Researchers explore ways to help older adults taper off and stop using sedatives

Older adults, especially those who are admitted to hospitals, are at risk for potentially dangerous side effects if they are taking multiple medicines. Taking several medications at the same time is called polypharmacy.

23 Mar 2018

New ocular inserts allow patient's cornea to absorb more antibiotics

The anatomic and physiologic structure of the eyes constitutes by itself an important barrier when administering medicine. The amount of medicine that passes through the cornea by applying creams or drops is very limited and it is necessary to develop alternative, more effective ways of administering them ocularly.

22 Mar 2018

Graphic: Opioid painkiller is top prescription in 11 states

Americans fill about 4.5 billion prescriptions each year, at a cost of more than $323 billion. But what are we actually buying? In 11 states, the top prescriptions are opioid pain pills that are mixtures of acetaminophen and hydrocodone (brand names Vicodin and Norco), according to new data from GoodRx, an online prescription cost service.

22 Mar 2018

Pharmaceutical News

Omissions on death certificates lead to undercounting of opioid overdoses

Enclosed point-of-use filter enhances quality of API for kidney dialysis

Study uncovers more complex, elaborate role for the body’s macromolecular complexes

New long-acting delivery system has potential to lessen side effects from NRTIs

FDA-approved inhibitors could be repurposed to target ARID1A-mutant ovarian cancers

LSTM researchers show potential of novel antiparasitic drug to combat malaria

Antibiotic use linked to higher risk of severe viral disease in mice

Cell-penetrating 'nanodrills' could be new platform for intracellular drug delivery

Magnesium found to be effective for mild-to-moderate depression symptoms

MSU scientists test promising drug to prevent cancer in high-risk patients

New research does not support previous findings that antidepressants impact breastfeeding

Frequent and public opioid users may be best candidates for naloxone training

SLU researchers turn off excruciating chemo pain in animal model

Daily regimen of ibuprofen can ward off Alzheimer's disease, say neuroscientists

Initiating opioid analgesic decreases use of antipsychotics, benzodiazepines in Alzheimer's patients

New University of Bath project seeks to make injections safer

New survey aims to identify opioid prescription patterns by oral and maxillofacial surgeons

Researchers explore ways to help older adults taper off and stop using sedatives

New ocular inserts allow patient's cornea to absorb more antibiotics

Graphic: Opioid painkiller is top prescription in 11 states

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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