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Study tests therapeutic effect of conventional and new cancer drug combinations

Cancer is one of the major causes of death worldwide affecting 8.2 million of people per year, and in the US, the number of new cases will achieve 1.6 million in 2017. The global impact of this disease costs a trillion of dollars, which makes critical the development of new drugs and treatment against it.

28 Aug 2017

NSAIDs may not be safe for arthritis patients with cardiovascular risk, study shows

Ibuprofen is associated with increased blood pressure and hypertension compared to celecoxib in patients with osteoarthritis or rheumatoid arthritis and increased risk of cardiovascular disease, according to late-breaking results from the PRECISION-ABPM study presented today in a Hot Line Session at ESC Congress and published in EHJ.

28 Aug 2017

Anti-inflammatory therapy reduces incidence of lung cancer

In most clinical trials for cancer therapy, investigators test treatments in patients with advanced disease. But a recent cardiovascular secondary prevention study has given researchers a unique opportunity: to explore the effectiveness of giving a drug to patients before cancer emerges.

28 Aug 2017

Offshore rush for herpes vaccine roils debate over U.S. safety rules

Defying U.S. safety protections for human trials, an American university and a group of wealthy libertarians, including a prominent Donald Trump supporter, are backing the offshore testing of an experimental herpes vaccine.

28 Aug 2017

Catheter ablation provides better outcomes for AF patients than conventional drug therapies

Every year millions of people around the world are diagnosed with heart failure, a chronic, progressive condition where the heart is unable to pump enough oxygenated blood throughout the body.

28 Aug 2017

Studies reveal strategies for using shingles vaccine in arthritis patients

New research indicates that the live varicella-zoster vaccine--which is given to protect against shingles--elicits robust immune responses in patients when administered several weeks prior to the start of treatment with the arthritis drug tofacitinib.

28 Aug 2017

Drug combination superior in preventing further heart complications in people with vascular disease

A major international study has found that the combination of two drugs - rivaroxaban and aspirin -- is superior to aspirin alone in preventing further heart complications in people with vascular disease.

28 Aug 2017

Two anticlotting medicines better at reducing bleeding risk than triple therapy

Using just two anticlotting medicines for patients who have atrial fibrillation and have had a stent placed in a heart artery is safer than using the current standard treatment of three medications, according to a new study presented by Brigham and Women's Hospital cardiologist Christopher Cannon, MD, at the European Society of Cardiology and published simultaneously in The New England Journal of Medicine.

28 Aug 2017

ESCMID conference brings together renowned experts to address most pressing questions on vaccines

Registration is open for the 4th ESCMID Conference on Vaccines. New and old diseases in children and adults: unmet needs in Dubrovnik, Croatia, Friday 8 September to Sunday 10 September 2017. Registration for bona fide journalists is free.

26 Aug 2017

Women more often receive inadequate treatment to prevent cardiovascular events

Women at high risk of cardiovascular events are less likely to receive recommended statin doses for secondary prevention, according to results from the DYSIS study presented today at ESC Congress.

26 Aug 2017

Astex celebrates as breast cancer drug gets European marketing approval

Astex Pharmaceuticals, a pharmaceutical company dedicated to the discovery and development of novel small molecule therapeutics for oncology and diseases of the central nervous system, announced today that its long-standing pharmaceutical collaborator, Novartis, has received marketing approval in Europe for Kisqali (ribociclib) plus an aromatase inhibitor as a first-line treatment in post-menopausal women with hormone receptor positive, human epidermal growth factor receptor-2 negative (HR+/HER2-) locally advanced or metastatic breast cancer.

26 Aug 2017

Researchers use zebrafish animal model to explore drug-seeking behavior

As the opioid crisis escalates, the science behind addiction remains poorly understood. To address this need, researchers at University of Utah Health devised a system that allowed zebrafish, a small tropical fish, to self-administer doses of hydrocodone, an opioid commonly prescribed to people for pain.

26 Aug 2017

ACR applauds legislative and regulatory initiatives to expedite approval of new biosimilar therapies

"Expanding our patients' access to safe, effective, and affordable biologic and biosimilar therapies is a top priority of the rheumatology community.

26 Aug 2017

Vireo Health to join $3.8 million NIH study on medical marijuana treatment for adults with chronic pain

The National Institute of Health has awarded a $3.8 million research grant to Albert Einstein College of Medicine and Montefiore Health System for medical marijuana research, and Vireo Health of New York will be partners in the study.

26 Aug 2017

Cancer drug may inhibit growth of cysts in patients with inherited form of kidney disease

A cancer drug called bosutinib may inhibit the growth of cysts in patients with autosomal dominant polycystic kidney disease (ADPKD), according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology.

24 Aug 2017

Influenza vaccination rates in children may decrease without option of nasal spray

Influenza vaccination rates in children may have decreased for the 2016-17 influenza season because of a recommendation by the Centers for Disease Control and Prevention that the nasal spray version of the vaccine not be used, according to Penn State College of Medicine researchers.

24 Aug 2017

Researchers aim to develop dynamic therapeutics for combating antiviral drug resistance

Antiviral drug resistance has long been a problem in modern society. As viruses evolve, they develop resistance to antiviral drugs, which become less effective at treating diseases such as influenza.

24 Aug 2017

Rare transition metal can simplify design and preparation of antibody therapies

Rice University scientists have developed a method to efficiently modify natural antibodies that can deliver drugs to target cells. Adding a little extra metal is the key.

24 Aug 2017

High level of heart disease pipeline innovation could bridge unmet need in treating CVD

With over 1,400 products in active development, the innovation pipeline for cardiovascular disease (CVD) is extensive, with four key CVD indications – hypertension, heart failure, dyslipidemia and thrombosis – now accounting for around half of all pipeline innovation, according to GBI Research, a recognized leader in providing business information and analytics.

24 Aug 2017

Common obesity and diabetes drug could be used as novel way to lower brain pressure

Research led by the University of Birmingham, published today in Science Translational Medicine, has discovered that a drug commonly used to treat patients with either obesity or Type II diabetes could be used as a novel new way to lower brain pressure.

23 Aug 2017

Pharmaceutical News

Study tests therapeutic effect of conventional and new cancer drug combinations

NSAIDs may not be safe for arthritis patients with cardiovascular risk, study shows

Anti-inflammatory therapy reduces incidence of lung cancer

Offshore rush for herpes vaccine roils debate over U.S. safety rules

Catheter ablation provides better outcomes for AF patients than conventional drug therapies

Studies reveal strategies for using shingles vaccine in arthritis patients

Drug combination superior in preventing further heart complications in people with vascular disease

Two anticlotting medicines better at reducing bleeding risk than triple therapy

ESCMID conference brings together renowned experts to address most pressing questions on vaccines

Women more often receive inadequate treatment to prevent cardiovascular events

Astex celebrates as breast cancer drug gets European marketing approval

Researchers use zebrafish animal model to explore drug-seeking behavior

ACR applauds legislative and regulatory initiatives to expedite approval of new biosimilar therapies

Vireo Health to join $3.8 million NIH study on medical marijuana treatment for adults with chronic pain

Cancer drug may inhibit growth of cysts in patients with inherited form of kidney disease

Influenza vaccination rates in children may decrease without option of nasal spray

Researchers aim to develop dynamic therapeutics for combating antiviral drug resistance

Rare transition metal can simplify design and preparation of antibody therapies

High level of heart disease pipeline innovation could bridge unmet need in treating CVD

Common obesity and diabetes drug could be used as novel way to lower brain pressure

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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