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New strategy in antimicrobial peptides holds promise for combating multi-drug resistant bacteria

In an article published recently in Plos One, researchers from INRS-Institut Armand-Frappier Research Centre reported a strategy that could lead to the discovery of new cationic antimicrobial peptides (CAMPs) with greatly enhanced antimicrobial properties.

5 Apr 2017

Low-dose penicillin in early life changes behaviour and balance of gut microbes

In a landmark study, researchers at St. Joseph's Healthcare Hamilton and McMaster University have found that providing clinical (low) doses of penicillin to pregnant mice and their offspring results in long-term behavioural changes.

4 Apr 2017

Short-term fasting during chemotherapy may counteract side effects of common cancer drugs

A short-term fast appears to counteract increases in blood sugar caused by common cancer drugs and protect healthy cells in mice from becoming too vulnerable to chemotherapy, according to new research from the University of Southern California.

4 Apr 2017

Treating PCOS in adolescent girls may help prevent future subfertility, research suggests

In adolescent girls with polycystic ovary syndrome (PCOS), bringing the amount of abdominal visceral fat and liver fat down to normal restores ovulation, normalizes the symptoms of androgen excess, and may help prevent future subfertility, new research from Spain suggests.

4 Apr 2017

Study reveals potential new approach to treat posttraumatic stress disorder

A potential new approach to treat posttraumatic stress disorder: After taking the antibiotic doxycycline, study participants remembered an unpleasant event considerably less, as experiments conducted by a team of researchers from the University Psychiatric Hospital and the University of Zurich reveal.

4 Apr 2017

Scientists identify new gene that drives drug resistance in breast cancer

SCIENTISTS in Salford, UK, have identified a gene which is 'revving the engine of cancer' against the world's most common breast cancer drug.

4 Apr 2017

Pharmaceuticalization of today’s sleep

The pharmaceuticalisation of sleep, put simply, refers to the ways in which sleep becomes a site for manipulation or augmentation through pharmaceutical use. There are different ways in which sleep can be pharmaceuticalised – for example we can use pharmaceuticals to induce sleep, to consolidate broken sleep, or to prevent or delay sleep.

4 Apr 2017

KU Leuven-led consortium to develop new vaccine that protects against rabies and yellow fever

Rabies and yellow fever claim ten thousands of lives each year. Vaccines already exist but various drawbacks that hinder their efficient distribution.

4 Apr 2017

Common antibiotic can disrupt formation of negative associations in the brain, research reveals

The common antibiotic doxycycline can disrupt the formation of negative associations in the brain, according to new research from UCL and the University of Zurich.

4 Apr 2017

WHO deployed 3.5 million doses of vaccine in response to yellow fever outbreak in Brazil

In response to the yellow fever outbreak currently on-going in Brazil some 3.5 million doses of vaccine from the emergency stockpile were deployed to the country through the International Coordinating Group (ICG) on Vaccine Provision for yellow fever.

3 Apr 2017

Horizon 2020 program selects Precision NanoSystems’ NanoAssemblr platform to develop RNA medicines

Precision NanoSystems NanoAssemblr platform has been selected for the controlled manufacture of nanomedicines as part of the multinational B-SMART (Brain-Specific, Modular and Active RNA Therapeutics) translational research project.

From Precision NanoSystems Inc. 3 Apr 2017

Maternal Tdap vaccination during pregnancy reduces pertussis risk in infants

Among infants of women who received the Tdap pertussis booster vaccine during pregnancy, the risk of contracting pertussis was reduced by an estimated 91 percent during the first two months of life - the critical period before they can receive their first childhood acellular pertussis (DTaP) vaccination.

3 Apr 2017

Novel highly potent SARDs may offer treatment option for advanced prostate cancer, study reports

Novel molecules called selective androgen receptor degraders (SARDs) may offer the next generation of treatment options for advanced prostate cancer, a new industry-sponsored study reports. The results of this research will be presented Saturday, April 1, at ENDO 2017, the 99th annual meeting of the Endocrine Society, in Orlando, Fla.

2 Apr 2017

Cow's milk decreases the body's ability to absorb oral thyroid hormone medication

Taking the common oral thyroid hormone medication levothyroxine with a glass of cow's milk significantly decreases the body's ability to absorb the drug, a preliminary study finds. Results will be presented Sunday at ENDO 2017, the Endocrine Society's 99th annual meeting in Orlando, Fla.

2 Apr 2017

FDA alerts consumers to voluntary recall of Mylan's EpiPen and EpiPen Jr Auto-Injector products

The U.S. Food and Drug Administration is alerting consumers to Meridian Medical Technologies' voluntary recall of 13 lots of Mylan's EpiPen and EpiPen Jr (epinephrine injection) Auto-Injector products used for emergency treatment of severe allergic reactions.

31 Mar 2017

Case Western Reserve and Q2 Pharma partner to develop antivirulence agents that disarm superbugs

Case Western Reserve University and Q2 Pharma Ltd., an Israeli biopharmaceutical company, have signed a two-year option to license small molecule, antivirulence technology to potentially treat bacterial infections such as methicillin-resistant staphylococcus aureus (MRSA), the first known scientific effort of its kind.

31 Mar 2017

New imaging tool that spots lung infections could help prevent antibiotic overuse

A new imaging tool that rapidly diagnoses bacterial lung infections could help prevent unnecessary use of antibiotics in intensive care units.

30 Mar 2017

University of Arkansas chemist receives $1.5 million NIH award to improve computer-aided drug design

A new $1.5 million award from the National Institutes of Health will allow a University of Arkansas chemist to develop mathematical models to improve the reliability and efficiency of computer-aided drug design. The research could reduce the cost of drug discovery and lead to improvements in public health.

30 Mar 2017

Adding anticoagulation medication use as EMS triage criteria could save lives of older adults

One change to field triage guidelines for emergency medical services responding to older adults with head trauma could make a "clinically important improvement over usual care," according to a study and accompanying editorial published earlier this month in Annals of Emergency Medicine ("Out-of-Hospital Triage of Older Adults With Head Injury: A Retrospective Study of the Effect of Adding 'Anticoagulation or Antiplatelet Medication Use' as a Criterion" and "Can an Out-of-Hospital Medication History Save Lives for Injured Older Adults?").

30 Mar 2017

Combining anticancer drug with antirheumatic produces improved effects against tumors

Scientists at EPFL and NTU have discovered that combining an anticancer drug with an antirheumatic produces improved effects against tumors. The discovery opens a new path for drug-drug synergy.

30 Mar 2017

Pharmaceutical News

New strategy in antimicrobial peptides holds promise for combating multi-drug resistant bacteria

Low-dose penicillin in early life changes behaviour and balance of gut microbes

Short-term fasting during chemotherapy may counteract side effects of common cancer drugs

Treating PCOS in adolescent girls may help prevent future subfertility, research suggests

Study reveals potential new approach to treat posttraumatic stress disorder

Scientists identify new gene that drives drug resistance in breast cancer

Pharmaceuticalization of today’s sleep

KU Leuven-led consortium to develop new vaccine that protects against rabies and yellow fever

Common antibiotic can disrupt formation of negative associations in the brain, research reveals

WHO deployed 3.5 million doses of vaccine in response to yellow fever outbreak in Brazil

Horizon 2020 program selects Precision NanoSystems’ NanoAssemblr platform to develop RNA medicines

Maternal Tdap vaccination during pregnancy reduces pertussis risk in infants

Novel highly potent SARDs may offer treatment option for advanced prostate cancer, study reports

Cow's milk decreases the body's ability to absorb oral thyroid hormone medication

FDA alerts consumers to voluntary recall of Mylan's EpiPen and EpiPen Jr Auto-Injector products

Case Western Reserve and Q2 Pharma partner to develop antivirulence agents that disarm superbugs

New imaging tool that spots lung infections could help prevent antibiotic overuse

University of Arkansas chemist receives $1.5 million NIH award to improve computer-aided drug design

Adding anticoagulation medication use as EMS triage criteria could save lives of older adults

Combining anticancer drug with antirheumatic produces improved effects against tumors

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