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Study provides new insights into side effects of antipsychotics

After much deliberation and anxiety, the family finally sought psychiatric help for their son. And the results were in a way, a relief.

28 Feb 2017

Biologists develop new way to inhibit cancer cell cleanup mechanism

The genomes of cancer cells--cells that do not obey signals to stop reproducing--are riddled with genetic mutations, causing them inadvertently to make many dysfunctional proteins.

28 Feb 2017

MIT researchers develop new machine to rapidly produce customized peptides

Manufacturing small proteins known as peptides is usually very time-consuming, which has slowed development of new peptide drugs for diseases such as cancer, diabetes, and bacterial infections.

27 Feb 2017

Universal public coverage of essential medicines could save over $4 billion per year, study finds

Universal public coverage of 117 essential medicines could address the needs of most Canadians for pharmaceutical drugs, and possibly save more than $4 billion a year, according to a new study published http://www.cmaj.ca/site/press/cmaj.161082.pdf in CMAJ.

27 Feb 2017

Alzheimer's drug prescribed off-label could accelerate cognitive decline for some patients

Donepezil, a medication that is approved to treat people with Alzheimer's disease, should not be prescribed for people with mild cognitive impairment without a genetic test.

24 Feb 2017

Dietary prebiotics can improve sleep after stress exposure, study suggests

In recent years, reams of research papers have shed light on the health benefits of probiotics, the "good bacteria" found in fermented foods and dietary supplements.

24 Feb 2017

Researchers discover promising target for treatment of leishmaniasis

Each year, about 2 million people contract leishmaniasis, a parasitic disease transmitted by the bite of a sand fly. The cutaneous form of the disease results in disfiguring skin ulcers that may take months or years to heal and in rare cases can become metastatic, causing major tissue damage.

24 Feb 2017

Novel antiviral drug can protect transplant patients against CMV infections

In a significant advance in improving the safety of donor stem cell transplants, a major clinical trial led by researchers at Dana-Farber Cancer Institute and Brigham and Women's Hospital has shown that a novel agent can protect against the most common viral infection that patients face after transplantation.

24 Feb 2017

New trial examines use of nanotechnology to improve delivery of drugs to HIV patients

Successful results of a University of Liverpool-led trial that utilised nanotechnology to improve drug therapies for HIV patients has been presented at the Conference on Retroviruses and Opportunistic Infections in Seattle, a leading annual conference of HIV research, clinical practice and progress.

24 Feb 2017

Scientists devise novel DNA vaccine approach against important cancer antigen targets

Scientists at The Wistar Institute and Inovio Pharmaceuticals, Inc. have devised a novel DNA vaccine approach through molecular design to improve the immune responses elicited against one of the most important cancer antigen targets. Study results were published in the journal Molecular Therapy.

24 Feb 2017

New investigational drug may help combat antibiotic-resistant global health threat

The deadly fungus, Candida auris, which has been found in hospitals, is resistant to entire classes of antimicrobial drugs, limiting treatment options for those infected.

24 Feb 2017

Researchers find link between low general cognitive ability and elevated risk of not taking statins

After a heart attack, it is important for patients to take medication that lowers cholesterol levels. In a new study published in the European Journal of Preventive Cardiology, researchers at Uppsala and Umeå Universities have found that general cognitive ability (intelligence) has a bearing, in the first year and two years after the heart attack, on how well men take statins prescribed for them.

24 Feb 2017

Structure of unique amyloid fibrils could lead to discovery of new antibiotics

The highly pathogenic Staphylococcus aureus bacteria is one of the five most common causes of hospital-acquired infections. In the US alone, approximately 500,000 patients at hospitals contract a staph infection. It is the bacteria responsible for MRSA, for which there is no vaccine.

24 Feb 2017

NR could potentially prevent chemotherapy-induced peripheral neuropathy in cancer patients

A new study in rats suggests that nicotinamide riboside (NR), a form of vitamin B3, may be useful for treating or preventing nerve pain (neuropathy) caused by chemotherapy drugs.

24 Feb 2017

Study reveals promising therapeutic approach that can be beneficial for older melanoma patients

Scientists at The Wistar Institute have shown that an anti-diabetic drug can inhibit the growth of melanoma in older patients by activating an anti-aging gene that in turn inhibits a protein involved in metastatic progression and resistance to targeted therapies for the disease.

24 Feb 2017

NSAIDs could potentially be repurposed as life-saving treatment for sepsis, research suggests

A potentially life-saving treatment for sepsis has been under our noses for decades in the non-steroidal anti-inflammatory drugs most people have in their medicine cabinets, a new University of Colorado Boulder study suggests.

23 Feb 2017

New analysis finds high rates of initial medication non-adherence in chronic treatments

A new analysis indicates that not obtaining a medication the first time it is prescribed-called initial medication non-adherence-is common among patients within the Catalan health system in Spain.

23 Feb 2017

New compounds with potent anticancer activity could lessen side effects of oncological treatments

The Universitat Jaume I, the Spanish Centre for Advanced Scientific Research and the University of Pavia have patented new compounds with potent anticancer activity in breast and colon tumour cell lines that have low toxicity in healthy cells, which can dramatically decrease side effects during chemotherapy treatment.

23 Feb 2017

Wastewater releases from oil and gas operations at West Virginia alter microbes, study finds

Wastewater from oil and gas operations -- including fracking for shale gas -- at a West Virginia site altered microbes downstream, according to a Rutgers-led study.

23 Feb 2017

Chemists discover cheaper, faster way to identify and test new drugs

Chemists at the University of Waterloo, SCIEX and Pfizer have discovered a new way to help the pharmaceutical industry identify and test new drugs, which could revolutionize drug development, and substantially reduce the cost and time drugs need to reach their market.

23 Feb 2017

Pharmaceutical News

Study provides new insights into side effects of antipsychotics

Biologists develop new way to inhibit cancer cell cleanup mechanism

MIT researchers develop new machine to rapidly produce customized peptides

Universal public coverage of essential medicines could save over $4 billion per year, study finds

Alzheimer's drug prescribed off-label could accelerate cognitive decline for some patients

Dietary prebiotics can improve sleep after stress exposure, study suggests

Researchers discover promising target for treatment of leishmaniasis

Novel antiviral drug can protect transplant patients against CMV infections

New trial examines use of nanotechnology to improve delivery of drugs to HIV patients

Scientists devise novel DNA vaccine approach against important cancer antigen targets

New investigational drug may help combat antibiotic-resistant global health threat

Researchers find link between low general cognitive ability and elevated risk of not taking statins

Structure of unique amyloid fibrils could lead to discovery of new antibiotics

NR could potentially prevent chemotherapy-induced peripheral neuropathy in cancer patients

Study reveals promising therapeutic approach that can be beneficial for older melanoma patients

NSAIDs could potentially be repurposed as life-saving treatment for sepsis, research suggests

New analysis finds high rates of initial medication non-adherence in chronic treatments

New compounds with potent anticancer activity could lessen side effects of oncological treatments

Wastewater releases from oil and gas operations at West Virginia alter microbes, study finds

Chemists discover cheaper, faster way to identify and test new drugs

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