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Antidepressant use in early pregnancy may increase risk of congenital anomalies in babies or stillbirths

Academics at Swansea University have carried out a dose-response analysis which suggests that pregnant women who take a specific type of antidepressant in early pregnancy have a small but significantly greater risk of having babies with major congenital anomalies (sometimes referred to as birth defects) or stillbirths compared with those who did not take these antidepressants.

2 Dec 2016

Alpha blockers benefit patients with larger kidney stones

Nearly one in 11 Americans will have a kidney stone in their lifetime, causing pain, sometimes missed work and, often, a lot of money.

2 Dec 2016

Hallucinogenic drug offers relief for people with cancer-related anxiety or depression

In a small double-blind study, Johns Hopkins researchers report that a substantial majority of people suffering cancer-related anxiety or depression found considerable relief for up to six months from a single large dose of psilocybin -- the active compound in hallucinogenic "magic mushrooms."

2 Dec 2016

Delay in giving adrenaline shots after cardiac arrest lowers survival rates of patients

Hospitals in which the administration of epinephrine to patients whose hearts have stopped is delayed beyond five minutes have significantly lower survival rates of those patients, a new study led by a cardiologist at UT Southwestern Medical Center finds.

2 Dec 2016

Monell Center receives Gates Foundation grant to support innovative global health research project

The Monell Center announced today that it has received a $345,000 grant from the Bill & Melinda Gates Foundation. The grant supports an innovative global health research project titled, "Developing Novel Pediatric Formulation Technologies for Global Health: Human Taste Assays."

1 Dec 2016

IUPUI scientists develop new synthetic method to shorten drug discovery and development process

Synthesizing useful new compounds is what pharmaceutical discovery and development is all about. Researchers at the School of Science at Indiana University-Purdue University Indianapolis have devised a method to substantially speed up the process.

1 Dec 2016

New device could revolutionize drug delivery to treat cancer and other diseases, study shows

A new study by Lyle Hood, assistant professor of mechanical engineering at The University of Texas at San Antonio, describes a new device that could revolutionize the delivery of medicine to treat cancer as well as a host of other diseases and ailments.

1 Dec 2016

New Baylor study aims to investigate antibiotic effect in children with ASD

Over the Thanksgiving holiday in 2012, John Rodakis, a father of a child with autism, observed his son's condition dramatically improve while taking a common antibiotic.

1 Dec 2016

Duke researchers modify popular drug-delivery technology to evade immune responses

Biomedical engineers at Duke University have reconfigured a popular drug-delivery technology to evade immune responses that have halted some clinical trials.

1 Dec 2016

Researchers develop efficient computational method to create new drugs

Researchers of the University of Barcelona have developed a more efficient computational method to identify new drugs.

1 Dec 2016

TSRI scientists discover potential drug candidate to suppress pain and itch

In a new study, scientists from the Florida campus of The Scripps Research Institute have identified a possible drug candidate that suppresses pain and itch in animal models.

1 Dec 2016

Treatment with biosimilar drug improves progression-free survival in breast cancer patients

Among women with metastatic breast cancer, treatment with a drug that is biosimilar to the breast cancer drug trastuzumab resulted in an equivalent overall response rate at 24 weeks compared with trastuzumab, according to a study published online by JAMA.

1 Dec 2016

Liverpool-led research consortium aims to reduce mother-to-child transmission of HIV

Researchers from the University of Liverpool's Institute of Translational Medicine have been awarded a grant of up to US$ 8.9 million (GBP £5.8m) to lead a multinational research consortium that aims to reduce mother-to-child transmission of HIV.

1 Dec 2016

Combination treatment may be valuable therapeutic option for HER2-negative metastatic breast cancer

Finding the ideal combination of targeted, hormonal and chemotherapeutic agents to treat HER2-negative metastatic breast cancer has been challenging researchers for decades.

1 Dec 2016

Type 2 diabetes drug may someday help combat breast and ovarian cancers

A drug used now to treat Type 2 diabetes may someday help beat breast and ovarian cancers, but not until researchers decode the complex interactions that in some cases help promote tumors, according to Rice University scientists.

30 Nov 2016

PCSK9 and HMGCR genetic variations that lower bad cholesterol affect risk of cardiovascular events

In a new study published in the December 1, 2016 issue of The New England Journal of Medicine, researchers at Brigham and Women's Hospital, and a collaboration of international researchers, studied variants in the genes encoding HMGCR and PCSK9 that affect cholesterol levels, and found that variants that lowered LDL (or "bad") cholesterol in each gene were associated with nearly identical protective effects on the risk of cardiovascular events per unit reduction in LDL cholesterol.

30 Nov 2016

First licensed vaccine could reduce burden in regions with high-levels of dengue infection

The first licensed vaccine for the potentially life-threatening dengue virus should only be used in moderate-to high impacted regions, new research has predicted.

30 Nov 2016

Researchers use microbubbles and ultrasound to transport drugs across blood–brain barrier

The impassable blood-brain barrier prevents microorganisms from entering our brain, however it also blocks medicines that could help treat Parkinson's, Alzheimer's and other neurodegenerative diseases.

30 Nov 2016

Researchers find differences in use of prescription analgesics between people with and without Alzheimer’s disease

Approximately one third of persons with Alzheimer’s disease use prescription medicines for pain after their diagnosis, reports a recent study conducted at the University of Eastern Finland.

30 Nov 2016

Researchers find way to make changes to enzyme-driven assembly line to improve antibiotics

Researchers from North Carolina State University have discovered a way to make pinpoint changes to an enzyme-driven "assembly line" that will enable scientists to improve or change the properties of existing antibiotics as well as create designer compounds.

30 Nov 2016

Pharmaceutical News

Antidepressant use in early pregnancy may increase risk of congenital anomalies in babies or stillbirths

Alpha blockers benefit patients with larger kidney stones

Hallucinogenic drug offers relief for people with cancer-related anxiety or depression

Delay in giving adrenaline shots after cardiac arrest lowers survival rates of patients

Monell Center receives Gates Foundation grant to support innovative global health research project

IUPUI scientists develop new synthetic method to shorten drug discovery and development process

New device could revolutionize drug delivery to treat cancer and other diseases, study shows

New Baylor study aims to investigate antibiotic effect in children with ASD

Duke researchers modify popular drug-delivery technology to evade immune responses

Researchers develop efficient computational method to create new drugs

TSRI scientists discover potential drug candidate to suppress pain and itch

Treatment with biosimilar drug improves progression-free survival in breast cancer patients

Liverpool-led research consortium aims to reduce mother-to-child transmission of HIV

Combination treatment may be valuable therapeutic option for HER2-negative metastatic breast cancer

Type 2 diabetes drug may someday help combat breast and ovarian cancers

PCSK9 and HMGCR genetic variations that lower bad cholesterol affect risk of cardiovascular events

First licensed vaccine could reduce burden in regions with high-levels of dengue infection

Researchers use microbubbles and ultrasound to transport drugs across blood–brain barrier

Researchers find differences in use of prescription analgesics between people with and without Alzheimer’s disease

Researchers find way to make changes to enzyme-driven assembly line to improve antibiotics

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