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Treatment using PARP inhibitor shrinks tumors in breast cancer patients with BRCA mutations

All 13 newly diagnosed breast cancer patients with BRCA mutations had their tumors shrink significantly when treated with a PARP inhibitor ahead of frontline presurgical chemotherapy in a pilot study at The University of Texas MD Anderson Cancer Center.

5 Oct 2016

Scientists report early-stage development of potential nerve agent antidote

Nerve agents are molecular weapons that invade the body and sabotage part of the nervous system, causing horrific symptoms and sometimes death within minutes. Few antidotes exist, and those that do must be administered soon after an attack.

5 Oct 2016

Many gay and bisexual men unaware that PrEP medication may reduce HIV risk

Only four in 10 gay and bisexual men in Baltimore without HIV are aware that pre-exposure prophylaxis medication (PrEP) may significantly reduce their risk of contracting the virus, even those who had recently visited a doctor or been tested for a sexually transmitted disease, new Johns Hopkins Bloomberg School of Public Health research suggests.

5 Oct 2016

JAK inhibitors show promise in restoring hair growth in patients with alopecia areata

Seventy-five percent of patients with moderate to severe alopecia areata--an autoimmune disease that causes patchy, and less frequently, total hair loss--had significant hair regrowth after treatment with ruxolitinib, reported researchers from Columbia University Medical Center. By the end of their treatment, average hair regrowth was 92 percent.

5 Oct 2016

BBI Solutions launches new range of antibodies for Galectin-3 biomarker

BBI Solutions has announced the launch of a range of antibodies for the biomarker Galectin-3. The antibodies complement BBI’s Galectin-3 antigen, which was also launched earlier this year.

5 Oct 2016

Scientists identify new pathway in the brain that can be targeted to alleviate depression

Northwestern Medicine scientists have discovered a new pathway in the brain that can be manipulated to alleviate depression. The pathway offers a promising new target for developing a drug that could be effective in individuals for whom other antidepressants have failed.

5 Oct 2016

New type of nanoparticles can deliver chemotherapy efficiently to cancer cells

Engineering researchers at The University of Texas at Austin have developed a new method that delivers chemotherapy directly and efficiently to individual cells.

4 Oct 2016

Prescription sleep aids may stimulate suicidal thoughts or actions

Prescription sleep aids appear to carry a rare risk of suicide, most typically when they cause the unexpected response of stimulating rather than quietening patients, researchers say.

4 Oct 2016

Two Zika vaccine candidates protect newborn mice against neurological damage

Two vaccines against Zika virus developed at the University of Pittsburgh School of Medicine have successfully conveyed immunity from female mice to pups conceived weeks after the mother's vaccination.

4 Oct 2016

Diabetes patients do not absorb insulin effectively when injecting into lipohypertrophy, confirm new studies

Two new studies provide evidence for the first time that insulin is not absorbed effectively when injected into Lipohypertrophy (LH).

4 Oct 2016

Study shows how common intestinal microbe protects the gut from attack by harmful bacteria

Antibiotics save millions of lives. But their tendency to kill helpful and harmful bacteria alike, coupled with the growing problem of antibiotic resistance, means that they are not without their downside.

4 Oct 2016

Antiseptic used for umbilical cord care ineffective in reducing newborn deaths in Africa

Despite significant reductions in neonatal mortality previously reported in south Asia, applying a chlorhexidine wash to newborns' umbilical cords in sub-Saharan Africa did not reduce deaths, a study led by researchers from the Boston University School of Public Health shows.

4 Oct 2016

Research findings question effectiveness of antibiotic treatment for diverticulitis

Antibiotics are advised in most guidelines on diverticulitis, which arises when one or more small pouches in the digestive tract become inflamed or infected.

4 Oct 2016

Discovery of rare flu-thwarting mutation could provide new strategy for live influenza vaccines

A rare and improbable mutation in a protein encoded by an influenza virus renders the virus defenseless against the body's immune system. This University of Rochester Medical Center discovery could provide a new strategy for live influenza vaccines in the future.

4 Oct 2016

HDAC inhibitors show potential to eliminate breast and ovarian cancer stem cells

A group of researchers, led by scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, has shown that histone deacetylase (HDAC) inhibitors have the potential to eliminate stubborn reservoirs of breast and ovarian cancer stem cells (CSCs).

4 Oct 2016

Study highlights impact of cognitive functions on oral cancer treatment

The development of oral cancer drugs as a modality therapy over the last decade has highlighted the problem of non-adherence. Only cancer drugs that are taken can actually work.

4 Oct 2016

High out-of-pocket costs may delay Medicare patients' access to novel targeted treatment for cancer

Significant out-of-pocket costs that cancer patients can face before Medicare insurance drug benefits kick in may delay the patients' treatment with a novel class of targeted therapies, according to a University of North Carolina Lineberger Comprehensive Cancer Center-led study.

4 Oct 2016

Researchers move one step closer to developing effective universal flu vaccine

Researchers at McMaster University and two American universities have taken another step closer to developing a much more effective, "one-punch" universal flu vaccine.

4 Oct 2016

Scientists develop new detection system to identify cocaine at low concentrations

Researchers from Valencia and the Basque Country have developed a new method to detect cocaine and mycoplasma at very low concentrations.

3 Oct 2016

Alternative therapies appear to be effective in ameliorating IBS symptoms

A new review looks at the evidence behind the effectiveness of complementary or alternative therapies-including probiotics, prebiotics, synbiotics, fiber, and herbal medicinal products-for the treatment of bowel disorders such as irritable bowel syndrome (IBS), functional constipation, and ulcerative colitis.

3 Oct 2016

Pharmaceutical News

Treatment using PARP inhibitor shrinks tumors in breast cancer patients with BRCA mutations

Scientists report early-stage development of potential nerve agent antidote

Many gay and bisexual men unaware that PrEP medication may reduce HIV risk

JAK inhibitors show promise in restoring hair growth in patients with alopecia areata

BBI Solutions launches new range of antibodies for Galectin-3 biomarker

Scientists identify new pathway in the brain that can be targeted to alleviate depression

New type of nanoparticles can deliver chemotherapy efficiently to cancer cells

Prescription sleep aids may stimulate suicidal thoughts or actions

Two Zika vaccine candidates protect newborn mice against neurological damage

Diabetes patients do not absorb insulin effectively when injecting into lipohypertrophy, confirm new studies

Study shows how common intestinal microbe protects the gut from attack by harmful bacteria

Antiseptic used for umbilical cord care ineffective in reducing newborn deaths in Africa

Research findings question effectiveness of antibiotic treatment for diverticulitis

Discovery of rare flu-thwarting mutation could provide new strategy for live influenza vaccines

HDAC inhibitors show potential to eliminate breast and ovarian cancer stem cells

Study highlights impact of cognitive functions on oral cancer treatment

High out-of-pocket costs may delay Medicare patients' access to novel targeted treatment for cancer

Researchers move one step closer to developing effective universal flu vaccine

Scientists develop new detection system to identify cocaine at low concentrations

Alternative therapies appear to be effective in ameliorating IBS symptoms

PhD researcher at LifeArc

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