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Oxytocin treatment improves social, emotional and behavioral problems among young kids with autism

A five week treatment with the synthetic hormone oxytocin significantly improved social, emotional and behavioral issues among young children with autism, according to University of Sydney research published today in Molecular Psychiatry.

27 Oct 2015

New drug combination may be effective against malignant melanoma

A team of Massachusetts General Hospital investigators has discovered a new combination of drugs that may be effective against one of the deadliest cancers, malignant melanoma. The combination - pairing a drug targeted against mutations in the BRAF gene with a second drug that targets another important signaling pathway - was discovered through one of the largest screens of cancer drug combinations conducted to date.

27 Oct 2015

Ipsen, EpiVax partner to create next generation botulinum neurotoxin and TSI therapeutics

Ipsen and the US company EpiVax, Inc. today announced that they have completed a collaborative project that provides a novel approach for creating next generation botulinum neurotoxin (BoNT) and Targeted Secretion Inhibitor (TSI) therapeutics.

27 Oct 2015

Patients with treatment-resistant autoimmune blood conditions may benefit from sirolimus

The immunosuppressant sirolimus is an effective and safe steroid-sparing therapy for children and young adults with highly treatment-resistant autoimmune blood conditions, according to a study published online today in Blood, the Journal of the American Society of Hematology.

27 Oct 2015

Nanofiber hydrogel infused with snake venom may stop bleeding, protect wounds

A nanofiber hydrogel infused with snake venom may be the best material to stop bleeding quickly, according to Rice University scientists.

27 Oct 2015

Advanced pancreatic cancer patients now have access to new FDA-approved drug, Onivyde

Patients with advanced pancreatic cancer now have access to the new FDA approved drug, Onivyde, that produced significant overall survival rates in an international clinical study conducted in part by researchers at HonorHealth Research Institute and the Translational Genomics Research Institute.

27 Oct 2015

Future Medicinal Chemistry releases themed issue higlighting the Academic Drug Discovery conference

Future Medicinal Chemistry, a leading MEDLINE-indexed journal published by Future Science Group, has released a themed issue dedicated to providing coverage of the presentations that took place at the 2015 Academic Drug Discovery Conference (Cambridge, UK), organized by SelectBio.

26 Oct 2015

Scalable production of gene therapy vectors: an interview with Frank Ubags

Gene therapy involves introducing genetic material into cells to replace missing or malfunctioning genes or to add a gene to express a beneficial protein in order to treat certain diseases, such as cancer or inherited disorders.

26 Oct 2015

Study: Pediatric patients prescribed more opioid medication than necessary following surgery

Although it is not uncommon for pediatric patients to be prescribed opioids to treat certain types of moderate to severe pain, new research suggests these patients may be prescribed more opioids than necessary following surgery. A study presented at the ANESTHESIOLOGY 2015 annual meeting found nearly 60 percent of opioids dispensed to pediatric patients following surgery remained unused, which could lead to the unused medication being abused by other adolescents in the household.

26 Oct 2015

Magnesium sulfate has protective effect on maternal fever during labor

Women who received magnesium sulfate during labor were less likely to develop maternal fever, a condition that can lead to a variety of complications in newborns including difficulty breathing, seizures, cerebral palsy and a condition known as "floppy baby syndrome," characterized by inadequate muscle tone, according to a retrospective study presented at the ANESTHESIOLOGY 2015 annual meeting in San Diego.

26 Oct 2015

Benzodiazepines and related drugs frequently used before and after diagnosis of Alzheimer's disease

Benzodiazepines and related drugs are initiated frequently in persons with Alzheimer's disease already before the diagnosis, and their use becomes even more common after the diagnosis, shows a recent study from the University of Eastern Finland.

26 Oct 2015

Routine use of antibiotics may not reduce infections in severe appendectomies

With acute appendicitis ranking among the nation's most common acute surgical emergencies, researchers studied the relatively routine use of post-operative antibiotics in complicated cases and found that they didn't reduce infections after surgery. They also found that patients who received post-operative antibiotics remained in the hospital up to one day longer than similar patients who had not received antibiotics.

26 Oct 2015

CHMP recommends approval of Cosentyx in Europe to treat patients with AS and PsA, says Novartis

Novartis announced today that the Committee for Medicinal Products for Human Use has recommended the approval of Cosentyx (secukinumab) in Europe to treat ankylosing spondylitis (AS) and psoriatic arthritis (PsA) patients.

26 Oct 2015

SAGE recommends pilot implementation of malaria vaccine to protect young children

The World Health Organization’s Strategic Advisory Group of Experts on Immunization (SAGE) recommended pilot projects to understand how to best use a vaccine that protects against malaria in young children.

26 Oct 2015

Inhibiting JAK family of enzymes promotes rapid hair growth, new study finds

Inhibiting a family of enzymes inside hair follicles that are suspended in a resting state restores hair growth, a new study from researchers at Columbia University Medical Center has found.

26 Oct 2015

FDA approves Yondelis (trabectedin) for treatment of specific soft tissue sarcomas

The U.S. Food and Drug Administration today approved Yondelis (trabectedin), a chemotherapy, for the treatment of specific soft tissue sarcomas (STS) – liposarcoma and leiomyosarcoma – that cannot be removed by surgery (unresectable) or is advanced (metastatic).

24 Oct 2015

Strensiq approved for treatment of patients with juvenile-onset HPP

Today, the U.S. Food and Drug Administration approved Strensiq (asfotase alfa) as the first approved treatment for perinatal, infantile and juvenile-onset hypophosphatasia (HPP).

24 Oct 2015

Amgen's IMLYGIC receives positive opinion from CHMP for treatment of melanoma

Amgen today announced that the Committee for Medicinal Products for Human Use, the scientific committee of the European Medicines Agency, has adopted a positive opinion recommending that IMLYGIC (talimogene laherparepvec) be granted approval for the treatment of adults with unresectable melanoma that is regionally or distantly metastatic (Stage IIIB, IIIC and IVM1a) with no bone, brain, lung or other visceral disease.

23 Oct 2015

Novel therapy gets FDA approval for patients with metastatic pancreatic adenocarcinoma

Today, The U.S. Food and Drug Administration approved a novel therapy for patients with metastatic pancreatic adenocarcinoma – the most common form of pancreatic cancer – whose disease has progressed following gemcitabine-based therapy, offering new hope against a disease that will claim the lives of more than 40,000 individuals this year.

23 Oct 2015

New combination treatment approved by FDA for metastatic pancreatic cancer

The U.S. Food and Drug Administration today approved Onivyde (irinotecan liposome injection), in combination with fluorouracil and leucovorin, to treat patients with advanced (metastatic) pancreatic cancer who have been previously treated with gemcitabine-based chemotherapy.

23 Oct 2015

Pharmaceutical News

Oxytocin treatment improves social, emotional and behavioral problems among young kids with autism

New drug combination may be effective against malignant melanoma

Ipsen, EpiVax partner to create next generation botulinum neurotoxin and TSI therapeutics

Patients with treatment-resistant autoimmune blood conditions may benefit from sirolimus

Nanofiber hydrogel infused with snake venom may stop bleeding, protect wounds

Advanced pancreatic cancer patients now have access to new FDA-approved drug, Onivyde

Future Medicinal Chemistry releases themed issue higlighting the Academic Drug Discovery conference

Scalable production of gene therapy vectors: an interview with Frank Ubags

Study: Pediatric patients prescribed more opioid medication than necessary following surgery

Magnesium sulfate has protective effect on maternal fever during labor

Benzodiazepines and related drugs frequently used before and after diagnosis of Alzheimer's disease

Routine use of antibiotics may not reduce infections in severe appendectomies

CHMP recommends approval of Cosentyx in Europe to treat patients with AS and PsA, says Novartis

SAGE recommends pilot implementation of malaria vaccine to protect young children

Inhibiting JAK family of enzymes promotes rapid hair growth, new study finds

FDA approves Yondelis (trabectedin) for treatment of specific soft tissue sarcomas

Strensiq approved for treatment of patients with juvenile-onset HPP

Amgen's IMLYGIC receives positive opinion from CHMP for treatment of melanoma

Novel therapy gets FDA approval for patients with metastatic pancreatic adenocarcinoma

New combination treatment approved by FDA for metastatic pancreatic cancer

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