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Salsalate drug offers new hope for treating Alzheimer's disease and FTD

Scientists from the Gladstone Institutes have discovered that salsalate, a drug used to treat rheumatoid arthritis, effectively reversed tau-related dysfunction in an animal model of frontotemporal dementia (FTD). Salsalate prevented the accumulation of tau in the brain and protected against cognitive impairments resembling impairments seen in Alzheimer's disease and FTD.

21 Sep 2015

$Common Alzheimer's disease drug increases bone density, reduces fracture risks$

Common Alzheimer's disease drug increases bone density, reduces fracture risks

The most common drug used to treat Alzheimer's disease increases bone mass in mice, according to one of the first research articles published in the new open access journal Heliyon. The authors of the study, from Saitama Medical University in Japan, say this means the drug could also be used to treat bone loss diseases like osteoporosis and periodontitis, following further clinical research.

21 Sep 2015

New Locilex microbiology data presented at ICAAC/ICC 2015 scientific conference

Dipexium Pharmaceuticals, Inc., a late-stage pharmaceutical company focused on the development and commercialization of Locilex (pexiganan cream 0.8%), and research collaborators, JMI Laboratories, announced that new Locilex microbiology data were presented at the American Society for Microbiology's Interscience Conference of Antimicrobial Agents and Chemotherapy and International Society of Chemotherapy's International Congress of Chemotherapy and Infection (ICAAC/ICC 2015) scientific conference in San Diego, California, September 17-21, 2015.

21 Sep 2015

Takeda Pharmaceutical's $2.37 billion settlement over Actos drug moves forward

MT Services LLC, a Lawsuit Settlement News Reporting Company which operates lawsuitsettlementnews.com, announced today that Takeda Pharmaceutical Co.'s $2.37 billion settlement over their diabetes drug Actos is going through and moving forward. Actos drug maker, Takeda, agreed to toss in another $100 million if enough claimants signed up with matching settlement criteria – 97% of the claims to be exact.

21 Sep 2015

Ups and downs of incorporating new treatment to reduce oxaliplatin-induced neuropathy

In this age of the 24-hour news cycle, instant access to all information everywhere, PubMed, LinkedIn, Facebook, Twitter and hundreds of other ways to glean and share knowledge beyond the traditional stack of printed journals delivered to their door, physicians continue to struggle to arm themselves with the most effective therapies.

21 Sep 2015

BGB324 shows enhanced tumour clearance in mouse carcinoma models

BerGenBio AS, an oncology biopharmaceutical company, has announced new preclinical data on lead compound, BGB324, in combination with immune checkpoint inhibitors, has been presented as a poster at CRI-CIMT-EATI-AACR - The Inaugural International Cancer Immunotherapy Conference: Translating Science into Survival, in New York.

21 Sep 2015

Glide Technologies, Cilian collaborate to develop solid dose formulation of recombinant influenza vaccine

Glide Technologies, the development company focused on solid dose formulations of therapeutics and vaccines, today announced that it has entered a collaboration with German biotechnology company Cilian AG to develop a solid dose formulation of Cilian's experimental recombinant influenza vaccine, CiFlu, for delivery using Glide's patient-friendly SDI delivery device.

21 Sep 2015

Report: Birth control pills cause significant increase in stroke risk

Birth control pills cause a small but significant increase in the risk of the most common type of stroke, according to a comprehensive report in the journal MedLink Neurology.

21 Sep 2015

Hypertension drugs block proteins that cause inflammation after traumatic brain injury

A new animal study shows that traumatic brain injury (TBI) affects the body as well as the brain and that treatment with hypertension drugs blocks the production of proteins related to inflammation.

21 Sep 2015

New study highlights gap in scientific knowledge about some diabetes drugs

A gap in scientific knowledge about a family of drugs that are used to treat Type 2 diabetes has been highlighted in a new study.

21 Sep 2015

Combination of TXA709 and cefdinir demonstrates synergistic antibacterial activity against MRSA

TAXIS Pharmaceuticals, a drug-discovery company focused on developing a new class of antibiotic agents to treat life-threatening, multidrug-resistant bacterial infections, announced the presentation of results demonstrating the synergistic antibacterial activity of its lead clinical candidate, TXA709, when combined with cefdinir, a third-generation cephalosporin antibiotic.

19 Sep 2015

Mylan releases Fluvastatin Sodium Extended-release Tablets in the U.S.

Mylan N.V. today announced the U.S. launch of Fluvastatin Sodium Extended-release Tablets, 80 mg, which is the generic version of Novartis' Lescol XL Tablets.

18 Sep 2015

Norwegian COPD sufferers prescribed more sedatives than psychiatric patients, shows study

New research has revealed that Norwegian COPD sufferers are prescribed even more sedatives than psychiatric patients. The researchers behind the study believe that this is problematic because the drugs in question are addictive and inhibit lung function.

18 Sep 2015

Specific biomarker predicts which HER2-negative breast cancer patients respond to targeted therapy

A multicenter team led by Case Western Reserve has demonstrated that brief exposure to a targeted therapy can tell doctors which HER2-negative patients will respond — and which should switch to another kind of treatment.

18 Sep 2015

Study reports use of new psychoactive drugs in US nationally representative survey

In recent years, there has been an increase in emergence and use of a variety of new drugs, so-called "novel psychoactive substances" (NPS) in the US and worldwide.

16 Sep 2015

New findings on amitriptyline drug could help develop antidepressants with novel mechanisms

Researchers in Japan have shown that several different classes of antidepressants increase early growth responses in astrocytes, star-shaped glial cells, which could help develop new treatments.

16 Sep 2015

ACP awarded $1,002,884 Cooperative Agreement to increase adult immunization rates in US

The American College of Physicians (ACP) was awarded a $1,002,884 Cooperative Agreement from the Centers for Disease Control and Prevention (CDC) to increase immunization rates in the United States.

16 Sep 2015

Common hypertension drugs worsen cardiovascular outcomes in hypertensive African Americans

Drugs commonly used to treat high blood pressure, and prevent heart attacks and strokes, are associated with significantly worse cardiovascular outcomes in hypertensive African Americans compared to whites, according to a new comparative effectiveness research study led by researchers in the Department of Population Health at NYU Langone Medical Center.

15 Sep 2015

Roflumilast drug could inhibit growth of brain tumor in children

Current drugs may stop working against the most common type of brain tumor in children, medulloblastoma, but the tumor could be targeted in a new way, according to Stanford University scientists.

15 Sep 2015

Cautiously-designed combination therapies may attenuate side effects associated with Alzheimer's drugs

BACE1 is the major drug target for Alzheimer's disease, but we know surprisingly little about its normal function in the CNS.

15 Sep 2015

Pharmaceutical News

Salsalate drug offers new hope for treating Alzheimer's disease and FTD

Common Alzheimer's disease drug increases bone density, reduces fracture risks

New Locilex microbiology data presented at ICAAC/ICC 2015 scientific conference

Takeda Pharmaceutical's $2.37 billion settlement over Actos drug moves forward

Ups and downs of incorporating new treatment to reduce oxaliplatin-induced neuropathy

BGB324 shows enhanced tumour clearance in mouse carcinoma models

Glide Technologies, Cilian collaborate to develop solid dose formulation of recombinant influenza vaccine

Report: Birth control pills cause significant increase in stroke risk

Hypertension drugs block proteins that cause inflammation after traumatic brain injury

New study highlights gap in scientific knowledge about some diabetes drugs

Combination of TXA709 and cefdinir demonstrates synergistic antibacterial activity against MRSA

Mylan releases Fluvastatin Sodium Extended-release Tablets in the U.S.

Norwegian COPD sufferers prescribed more sedatives than psychiatric patients, shows study

Specific biomarker predicts which HER2-negative breast cancer patients respond to targeted therapy

Study reports use of new psychoactive drugs in US nationally representative survey

New findings on amitriptyline drug could help develop antidepressants with novel mechanisms

ACP awarded $1,002,884 Cooperative Agreement to increase adult immunization rates in US

Common hypertension drugs worsen cardiovascular outcomes in hypertensive African Americans

Roflumilast drug could inhibit growth of brain tumor in children

Cautiously-designed combination therapies may attenuate side effects associated with Alzheimer's drugs

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