Breast Cancer News and Research

Latest Breast Cancer News and Research

CINJ commences enrollment in three-drug combination trial for breast cancer

Researchers at The Cancer Institute of New Jersey (CINJ) are enrolling patients for a clinical trial, which aims to evaluate a new drug for breast cancer that has spread (metastatic) in combination with two chemotherapy agents called doxorubicin and cyclophosphamide.

18 Jun 2012

Variations in microRNA expression within breast tumors can lead to sampling bias

Certain short strands of RNA, known as microRNAs (miRNAs), have been linked to the progression and metastasis of breast cancer and may provide information about prognosis. However, studies of miRNA expression profiles often report conflicting findings. While the potential for using miRNAs in breast cancer diagnosis is promising, scientists report in a new study published online today in The Journal of Molecular Diagnostics that differences in the amount and types of miRNA within breast tumors can be misleading.

15 Jun 2012

Study reveals molecular link between aging and cancer

It has long been known that cancer is a disease of aging, but a molecular link between the two has remained elusive.

15 Jun 2012

Study investigates how breast cancer cells migrate to bone

Breast cancer cells frequently move from their primary site and invade bone, decreasing a patient's chance of survival. This process of metastasis is complex, and factors both within the breast cancer cells and within the new bone environment play a role. In next week's Journal of Biological Chemistry "Paper of the Week," Roger Gomis and colleagues at the Institute for Research in Biomedicine in Spain investigated how breast cancer cells migrate to bone.

14 Jun 2012

Unnecessary medical imaging can reduce risk of breast cancer in women

A report issued by the Institute of Medicine (IOM) last December reviewed all the available scientific data compiled to date about potential environmental risks of breast cancer-factors such as pesticides, beauty products, household chemicals, and the plastics used to make water bottles.

12 Jun 2012

Normal p53 gene makes breast cancer chemotherapy with doxorubicin less effective

Presence of normal p53, a tumor suppressor gene, instead of a mutated version, makes breast cancer chemotherapy with doxorubicin less effective. The preclinical study led by MD Anderson scientists was published today in the journal Cancer Cell.

12 Jun 2012

Premature cancer death risk may be increased by dental plaque

Persistent dental plaque may increase the risk of dying early from cancer, suggests an observational study published in the online journal BMJ Open.

12 Jun 2012

Investigational drug slows metastatic breast cancer progression

Trastuzumab emtansine significantly delays disease progression compared with standard therapy in women with human epidermal growth factor receptor-2-positive metastatic breast cancer, show study data presented at the American Society of Clinical Oncology Annual Meeting in Chicago, Illinois, USA.

11 Jun 2012

ColoPrint aids prediction of colorectal cancer relapse

A novel microarray-based 18-gene expression tool known as ColoPrint significantly improves prognostic accuracy in stage II colon cancer patients who have undergone surgery, suggest study findings.

11 Jun 2012

Distinct cancer 'signatures' may help predict response to estrogen-lowering therapy

Decoding the DNA of patients with advanced breast cancer has allowed scientists to identify distinct cancer "signatures" that could help predict which women are most likely to benefit from estrogen-lowering therapy, while sparing others from unnecessary treatment.

11 Jun 2012

BioSante to initiate two new LibiGel Phase III efficacy trials in FSD, HSDD

BioSante Pharmaceuticals, Inc., announced today that the Company plans to initiate two new LibiGel Phase III efficacy trials. This decision is based on an extensive analysis of previous efficacy data, consultation with key opinion leaders (KOLs) in female sexual dysfunction, testosterone therapy and placebo effects, as well as a meeting with the U.S. Food and Drug Administration (FDA).

11 Jun 2012

ADAM28 inhibits VWF-mediated cancer cell apoptosis and enhances lung metastases

ADAM28, a metalloproteinase belonging to the ADAM gene family, cleaves the von Willebrand factor (VWF) and inhibits VWF-mediated cancer cell apoptosis, thereby enhancing lung metastases, so inhibiting its expression gives a substantial reduction in lung metastases, according to a study published June 8 in the Journal of The National Cancer Institute.

11 Jun 2012

Genentech receives FDA approval for Perjeta to treat HER2-positive metastatic breast cancer

The U.S. Food and Drug Administration today approved Perjeta (pertuzumab), a new anti-HER2 therapy, to treat patients with HER2-positive late-stage (metastatic) breast cancer.

10 Jun 2012

New data supports clinical role of Cambridge Heart’s MTWA test in managing patients at risk of SCA

Cambridge Heart, Inc., a developer of non-invasive diagnostic tests for cardiac disease, today announced that results of a prospective, 155-patient trial reinforce the value of the Microvolt T-Wave Alternans (MTWA) test as a predictor of life-threatening heart rhythms and Sudden Cardiac Death (SCD).

7 Jun 2012

Debiopharm announces results from Debio 0932 Phase I study on cancer

Debiopharm Group (Debiopharm), a Swiss-based global biopharmaceutical group of companies with a focus on the development of prescription drugs that target unmet medical needs and companion diagnostics, presented results of a Phase I open-label dose-escalation study with Debio 0932, an oral Heat Shock Protein 90 (HSP90) inhibitor in clinical development as an anti-cancer agent.

7 Jun 2012

CCR5 antagonists may also help prevent aggressive breast cancers from metastasizing

The HIV drugs known as CCR5 antagonists may also help prevent aggressive breast cancers from metastasizing, researchers from the Kimmel Cancer Center at Jefferson suggest in a preclinical study published in a recent issue of Cancer Research.

7 Jun 2012

Work pattern affects night shift–breast cancer link

The risk for breast cancer increases significantly with both the number of years of night shift work and the cumulative number of shifts, Danish researchers have discovered.

6 Jun 2012

Better diagnosis of breast cancer could come from simple blood test

Scientists have discovered that a simple blood test could lead to better diagnosis and treatment for early-stage breast cancer patients, according to an Article published Online First in The Lancet Oncology.

6 Jun 2012

Cardio-protective drug during cancer treatment may prevent heart damage in children

About 75 percent of children with leukemia who take chemotherapy face life-threatening heart problems as they age, but an international study led by a University of Rochester Medical Center investigator shows that giving a cardio-protective drug during cancer treatment may prevent the damage.

6 Jun 2012

bioTheranostics’ CancerTYPE ID molecular test improves overall survival for patients with CUP

bioTheranostics, developer of innovative oncology diagnostic tests and solution provider for metastatic cancer, today announced study results showing that tumor profiling with its CancerTYPE ID molecular test helped guide site-specific chemotherapy and improve overall survival for patients with carcinoma of unknown primary site.

6 Jun 2012

Breast Cancer News and Research

Latest Breast Cancer News and Research

CINJ commences enrollment in three-drug combination trial for breast cancer

Variations in microRNA expression within breast tumors can lead to sampling bias

Study reveals molecular link between aging and cancer

Study investigates how breast cancer cells migrate to bone

Unnecessary medical imaging can reduce risk of breast cancer in women

Normal p53 gene makes breast cancer chemotherapy with doxorubicin less effective

Premature cancer death risk may be increased by dental plaque

Investigational drug slows metastatic breast cancer progression

ColoPrint aids prediction of colorectal cancer relapse

Distinct cancer 'signatures' may help predict response to estrogen-lowering therapy

BioSante to initiate two new LibiGel Phase III efficacy trials in FSD, HSDD

ADAM28 inhibits VWF-mediated cancer cell apoptosis and enhances lung metastases

Genentech receives FDA approval for Perjeta to treat HER2-positive metastatic breast cancer

New data supports clinical role of Cambridge Heart’s MTWA test in managing patients at risk of SCA

Debiopharm announces results from Debio 0932 Phase I study on cancer

CCR5 antagonists may also help prevent aggressive breast cancers from metastasizing

Work pattern affects night shift–breast cancer link

Better diagnosis of breast cancer could come from simple blood test

Cardio-protective drug during cancer treatment may prevent heart damage in children

bioTheranostics’ CancerTYPE ID molecular test improves overall survival for patients with CUP

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