T Cell News and Research

Latest T Cell News and Research

New partnership aims to advance predictive tests for multiple myeloma in Ireland

By combining genomic testing and next generation sequencing technology, a new partnership led by RCSI researchers aims to advance predictive tests for multiple myeloma, the second most common blood cancer in Ireland.

18 Sep 2020

S-pseudotyped VLPs offer promising COVID-19 vaccine platform

A new study published on the preprint server bioRxiv* in September 2020 reports on a Moloney murine leukemia virus (MLV) platform that produces VLPs expressing the important spike antigen of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

18 Sep 2020

Key China COVID-19 study produced results that influenced subsequent research on coronavirus

Early in the onset of the COVID-19 pandemic, a small study in China produced results that influenced subsequent research on the virus.

18 Sep 2020

Study invalidates Ebselen and other broad-spectrum SARS-CoV-2 Mpro inhibitors

Other novel compounds with Mpro inhibitory activity have also been claimed to have antiviral activity. These include ebselen, disulfiram, tideglusib, carmofur, shikonin, and PX-12. A new research paper discusses the role of these molecules as potential Mpro inhibitors in the prevention of SARS-CoV-2 infection.

18 Sep 2020

Cellular recyclers could be used to eliminate the driver of cancer's aggressiveness

"Do not erase." "Recycle me." "Free to a good home." Humans post these signs to indicate whether something has value or not, whether it should be disposed of or not.

18 Sep 2020

Scientists investigate how psychedelic drugs interact with brain cells at the molecular level

Psychedelic drugs such as LSD, psilocybin, and mescaline cause severe and often long-lasting hallucinations, but they show great potential in treating serious psychiatric conditions, such as major depressive disorder.

18 Sep 2020

Study shows how fiber shapes the structure of plant cell walls

The secret of how fibre shapes the structure of plant cell walls has been revealed, with potentially wide-ranging applications ranging from nutrition and health to agriculture.

18 Sep 2020

Study sheds new light on the mechanism of COVID-19 infection

The spike protein on the surface of the SARS-CoV-2 coronavirus can adopt at least ten distinct structural states, when in contact with the human virus receptor ACE2, according to research from the Francis Crick Institute published in Nature today.

18 Sep 2020

Researchers describe details of protein linked to genetically inherited Parkinson's disease

In August, a team of researchers at the University of California San Diego published groundbreaking back-to-back studies describing unprecedented details of a protein linked to genetically inherited Parkinson's disease.

18 Sep 2020

Engineered, high-affinity ACE2 receptors neutralize SARS-CoV-2

In a study published in the preprint server bioRxiv, researchers from the Kyoto Prefectural University of Medicine and Osaka University Japan, discuss how they engineered ACE2 to enhance its affinity to RBD in human cells.

17 Sep 2020

Animal data supports efficacy of baricitinib vs SARS-COV-2

The high burden of disease caused by the COVID-19 pandemic has led to much research on effective ways to mitigate the health, social, and economic impact of the spread of the infection. A recent study published on the preprint server bioRxiv* in September 2020 reports on the characteristics of the drug baricitinib when used as monotherapy to treat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Sep 2020

T cells on the front line of COVID-19 response

In the new study, published in the journal Cell, the team has found that the uncoordinated responses produced by the immune system, especially in people who are more than 65 years old, maybe the reason why older adults are more at risk.

17 Sep 2020

MDI Biological Laboratory receives €280,000 to address the problem of tendon injury

Modern medicine has made tremendous strides in replacing organs and hips. But what about those all-important tendons, which enable joint movement by connecting muscle to bone? Tendon injuries, such as those in the knee, elbow, Achilles tendon and rotator cuff (shoulder) exact a huge cost in terms of health care, productivity and quality of life.

17 Sep 2020

Study finds wide variation in levels and anti-tumor effectiveness of a common cancer drug

When used to manage infections, the drug itraconazole is generally given at a single, fixed dose to all patients.

17 Sep 2020

Researchers identify cause for thrombosis in COVID-19 patients

A new University of Kentucky College of Medicine study may provide answers for why so many COVID-19 patients experience thrombosis, or the formation of blood clots that obstruct blood flow through the circulatory system.

17 Sep 2020

Biomarker predicts disease severity in COVID-19 patients

Airway cell analyses showing an activated immune axis could pinpoint the COVID-19 patients who will most benefit from targeted therapies.

17 Sep 2020

New drug candidate suppresses SARS-CoV-2 replication

Researchers at Stanford University and Utah State University have developed a novel inhibitor of the coronavirus main protease (Mpro) that effectively suppresses the viral replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Sep 2020

Flexibility of glycosylated membrane-bound ACE2 suggests mechanical energy source in opening of SARS-CoV-2 spike

Angiotensin, Angiotensin-Converting Enzyme 2, Cell, Coronavirus, Enzyme, Glycoprotein, Neck, Protein, Receptor, Respiratory, Severe Acute Respiratory, Severe Acute Respiratory Syndrome, Syndrome, Virus, SARS-CoV-2, Coronavirus Disease COVID-19,

17 Sep 2020

Novel mechanism that may confer protection against glaucoma identified

A team of researchers from LSU Health New Orleans Neuroscience Center of Excellence and the University of Copenhagen provides the first evidence that patients with ocular hypertension may exhibit superior antioxidant protection that promotes resistance to the elevated intraocular pressure associated with glaucoma.

17 Sep 2020

Could pineapples be a new weapon against COVID-19?

Results of a recent research endeavor from the United States indicate that bromelain or bromelain rich pineapple stem may be utilized as an antiviral agent against coronavirus disease (COVID-19), but also for potential future coronavirus outbreaks. This exciting paper is currently available on the bioRxiv preprint server.

17 Sep 2020

T Cell News and Research

Latest T Cell News and Research

New partnership aims to advance predictive tests for multiple myeloma in Ireland

S-pseudotyped VLPs offer promising COVID-19 vaccine platform

Key China COVID-19 study produced results that influenced subsequent research on coronavirus

Study invalidates Ebselen and other broad-spectrum SARS-CoV-2 Mpro inhibitors

Cellular recyclers could be used to eliminate the driver of cancer's aggressiveness

Scientists investigate how psychedelic drugs interact with brain cells at the molecular level

Study shows how fiber shapes the structure of plant cell walls

Study sheds new light on the mechanism of COVID-19 infection

Researchers describe details of protein linked to genetically inherited Parkinson's disease

Engineered, high-affinity ACE2 receptors neutralize SARS-CoV-2

Animal data supports efficacy of baricitinib vs SARS-COV-2

T cells on the front line of COVID-19 response

MDI Biological Laboratory receives €280,000 to address the problem of tendon injury

Study finds wide variation in levels and anti-tumor effectiveness of a common cancer drug

Researchers identify cause for thrombosis in COVID-19 patients

Biomarker predicts disease severity in COVID-19 patients

New drug candidate suppresses SARS-CoV-2 replication

Flexibility of glycosylated membrane-bound ACE2 suggests mechanical energy source in opening of SARS-CoV-2 spike

Novel mechanism that may confer protection against glaucoma identified

Could pineapples be a new weapon against COVID-19?

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T Cell News and Research

Latest T Cell News and Research

Immunology eBook

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

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