Vaccine News and Research

Latest Vaccine News and Research

Highly conserved RNA structures are essential for SARS-CoV-2 replication and pathogenesis

A recent study from the University of North Carolina at Chapel Hill revealed how selective pressure helps in preserving secondary RNA structures in coronavirus genomes, unveiling a pivotal role of these elements in viral replication and pathogenesis. The paper is currently available on the bioRxiv* preprint server.

17 Jun 2020

UVA doctors and students launch 12-part COVID-19 podcast series

UVA School of Medicine physicians and students have launched a COVID-19 podcast series that includes advice to protect your health along with a behind-the-scenes look at UVA Health's patient care and research.

17 Jun 2020

Nanosponges could attack and neutralize SARS-COV-2 virus

Nanoparticles cloaked in human lung cell membranes and human immune cell membranes can attract and neutralize the SARS-CoV-2 virus in cell culture, causing the virus to lose its ability to hijack host cells and reproduce.

17 Jun 2020

Cobra and AstraZeneca sign supply agreement for manufacture of COVID-19 vaccine candidate

Cobra Biologics, part of the Cognate BioServices family, an international CDMO for biologics and pharmaceuticals, today announced it has signed a supply agreement with AstraZeneca UK Ltd. to provide GMP manufacture of the adenovirus vector-based COVID-19 vaccine candidate AZD1222, previously known as ChAdOx1 n-CoV-19.

From AstraZeneca 17 Jun 2020

BIA Separations launches novel PrimaS ligand technology to facilitate development of advanced therapies

BIA Separations, a leading bio-chromatography development and manufacturing company, today announced the introduction of its novel PrimaS ligand technology.

17 Jun 2020

Researchers take actions to reduce hospitalizations and deaths from COVID-19

Infectious disease experts from Fred Hutchinson Cancer Research Center and UW Medicine are advocating for earlier actions to reduce hospitalizations and deaths from COVID-19.

17 Jun 2020

An improved tetravalent antibody blocks SARS-CoV-2 infection

A new study published on the preprint server bioRxiv* in June 2020 shows the potential of a new fusion molecule called a biparatopic protein to inhibit viral interaction with the host cell ACE2 receptor. This could lead to therapeutic applications.

17 Jun 2020

SARS-CoV-2 mutated spike proteins show variations in cell entry

A new study by Japanese scientists published on the preprint server bioRxiv* in June 2020 shows that the D614g mutation in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein can enhance the infectivity of the virus while leaving it vulnerable to neutralization by antibodies.

17 Jun 2020

Novel ACE2-antibody fusion molecules show anti-SARS-CoV-2 activity

Now, in a new study published on the preprint server, bioRxiv researchers in the U.S. investigated a soluble version of ACE2 for SARS-CoV-2 viral neutralization activity.

17 Jun 2020

Norway pulls coronavirus contact tracing App due to privacy concerns

Amid the coronavirus pandemic, many countries have launched contact tracing apps to help contain the spread of the virus. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread across most of the world, now infecting more than 8.17 million people; hence, extensive contact tracing is a vital tool to prevent its vast spread.

17 Jun 2020

Scientists isolate powerful SARS-CoV-2 -neutralizing antibodies from COVID-19 patients

A new study has shown that potent antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could help protect against COVID-19 infection. Preliminary results in animal studies have so far proven successful. The study titled, "Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model," was published in the latest issue of the journal Science.

17 Jun 2020

Antibiotic X-206 effective against SARS-CoV-2 in vitro

The current study published on the preprint server bioRxiv aims to understand how these compounds affect SARS-CoV-2 in vitro. The researchers from Aarhus University in Denmark examined 11 natural PEIs, with a single synthetic analog, screening them for inhibitory activity against the CPE of SARS-CoV-2 infecting cultured cells with overexpression of TMPRSS2, a serine protease that is instrumental in cleaving the spike protein of the virus.

16 Jun 2020

Researchers develop a simple tool for making mouse models of COVID-19

Until there are effective treatments or vaccines, the COVID-19 pandemic will remain a significant threat to public health and economies around the world. A major hurdle to developing and testing new anti-viral therapies and vaccines for COVID-19 is the lack of good, widely available animal models of the disease.

16 Jun 2020

Key factors to "flattening the curve": Western Washington state's COVID-19 experience

Despite having the first confirmed case of coronavirus and the first major COVID-19 outbreak in the United States, the state of Washington implemented a response plan that kept its death rate the lowest among all states that have had major outbreaks.

16 Jun 2020

New discovery could open door to next generation malaria vaccine

In an unprecedented first, scientists at Seattle Children's Research Institute have developed a genetically attenuated parasite (GAP) that arrests late in the liver stage of human malaria.

16 Jun 2020

Study reports structure of enzyme activator for high pathogenic avian influenza

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causing the current pandemic of COVID-19, is the focus of many investigators seeking to find an effective vaccine or therapeutic. Among the potential targets are various protease enzymes suspected of allowing the virus to gain entry to host cells and establish a successful infection.

16 Jun 2020

New model predicts patients’ likelihood of testing positive for COVID-19

Cleveland Clinic researchers have developed the world's first risk prediction model for healthcare providers to forecast an individual patient's likelihood of testing positive for COVID-19 as well as their outcomes from the disease.

16 Jun 2020

Multilevel interventions improve overall rate of HPV vaccinations

New research from Boston Medical Center shows that providing education and training to pediatric and family medicine providers about the importance of human papillomavirus vaccines, in tandem with healthcare systems changes including starting an HPV vaccination series before the age of 11, improves the overall rate of HPV vaccinations among adolescent patients.

15 Jun 2020

Human antibodies provide powerful protection against SARS-CoV-2 in animal tests

A team led by Scripps Research has discovered antibodies in the blood of recovered COVID-19 patients that provide powerful protection against SARS-CoV-2, the coronavirus that causes the disease, when tested in animals and human cell cultures.

15 Jun 2020

Tracing coronavirus habitats with genomics

Now, a new study by researchers at the University of Ottawa and published on the preprint server bioRxiv in June 2020 reports the differences in genomes of viruses that are exposed to antiviral proteins vs. those that are not. This host-derived pressure on the virus to adapt may help devise newer ways to build an effective vaccine.

15 Jun 2020

Vaccine News and Research

Latest Vaccine News and Research

Highly conserved RNA structures are essential for SARS-CoV-2 replication and pathogenesis

UVA doctors and students launch 12-part COVID-19 podcast series

Nanosponges could attack and neutralize SARS-COV-2 virus

Cobra and AstraZeneca sign supply agreement for manufacture of COVID-19 vaccine candidate

BIA Separations launches novel PrimaS ligand technology to facilitate development of advanced therapies

Researchers take actions to reduce hospitalizations and deaths from COVID-19

An improved tetravalent antibody blocks SARS-CoV-2 infection

SARS-CoV-2 mutated spike proteins show variations in cell entry

Novel ACE2-antibody fusion molecules show anti-SARS-CoV-2 activity

Norway pulls coronavirus contact tracing App due to privacy concerns

Scientists isolate powerful SARS-CoV-2 -neutralizing antibodies from COVID-19 patients

Antibiotic X-206 effective against SARS-CoV-2 in vitro

Researchers develop a simple tool for making mouse models of COVID-19

Key factors to "flattening the curve": Western Washington state's COVID-19 experience

New discovery could open door to next generation malaria vaccine

Study reports structure of enzyme activator for high pathogenic avian influenza

New model predicts patients’ likelihood of testing positive for COVID-19

Multilevel interventions improve overall rate of HPV vaccinations

Human antibodies provide powerful protection against SARS-CoV-2 in animal tests

Tracing coronavirus habitats with genomics

Event guide: The 5th mRNA-Based Therapeutics Summit Europe eBook

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Vaccine News and Research

Latest Vaccine News and Research

Event guide: The 5th mRNA-Based Therapeutics Summit Europe eBook

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

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