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Trastuzumab and chemo improves survival in women with operable HER-2 positive breast cancer

A recent meta-analysis of five major breast cancer trials has confirmed that combination treatment with the antibody trastuzumab and chemotherapy improves survival in women with operable HER-2 positive breast cancer.

9 Jul 2007

New score for predicting the risk of heart disease

A new score for predicting the risk of heart disease gives a more accurate measure of how many UK adults are at risk of developing the disease - and which adults are most likely to benefit from treatment.

8 Jul 2007

Pre-exposure prophylaxis for HIV infection

Clinical trials of pre-exposure prophylaxis - that is giving anti-retroviral drugs to non-HIV-infected individuals to prevent them becoming infected - are exploring whether the approach could lead to a large decrease in transmission of the virus with few or no side effects.

8 Jul 2007

Darunavir-ritonavir shows benefits for patients with HIV

Darunavir-ritonavir should be considered as a treatment option across the range of treatment-experienced patients with HIV infection, conclude Jose Madruga (Centro de Referencia e Treinamento DST/AIDS, Sao Paulao, Brazil) and colleagues in an Article in this week's issue of The Lancet.

8 Jul 2007

Etravirine effective for HIV supression

Treatment with TMC125 (etravirine) leads to better virological suppression than placebo as part of antiretroviral therapy in patients with documented resistance to non-nucleoside reverse transcriptase inhibitors (NNRTIs), conclude two randomised trials in this week's issue of The Lancet.

8 Jul 2007

Organic tomatoes a better health option

According to a new study organic food may be a better health option after all.

8 Jul 2007

It may be 'altitude sickness' rather than jet lag but you still feel rotten

A study has revealed that many of the effects of long-distance flight which are usually put down to jet lag and fatigue, may in fact be altitude sickness.

5 Jul 2007

Positive role models make a difference

'Macho, bullying, and unfriendly workplace cultures' are a common experience of ethnic minority women in the UK labour market and workplace, according to a major new study published today, (Thursday, 5 July 2007) yet good management and positive role models make a difference.

5 Jul 2007

Use of implantable cardioverter defibrillators in Canada

The use of life-saving implantable cardioverter defibrillators in Canada is rising, but it is still significantly less than that in the United States.

4 Jul 2007

Rimonabant may prevent and treat obesity-related liver disease

A new study on the effect of the anti-obesity drug rimonabant on liver function in obese rats found that it reduced markers of liver damage, decreased levels of pro-inflammatory proteins, and improved lipid profiles.

4 Jul 2007

Antidepressant warnings linked to decreased prescription rates among children

Regulatory warnings regarding the risk of suicidal thoughts and behaviors appear to be associated with reductions in the number of antidepressant medication prescriptions among children and adolescents covered by Tennessee's expanded Medicaid program, according to a report in the July issue of Archives of Pediatrics & Adolescent Medicine.

4 Jul 2007

IgG, an immune system antibody significantly higher in spinal fluid of blacks with MS

An antibody frequently used as a diagnostic marker for multiple sclerosis (MS) is present at greater levels in the cerebrospinal fluid of blacks with MS than Caucasians with the disease.

4 Jul 2007

30 percent of Americans report having some form of alcohol use disorder

About 30 percent of Americans report having some form of alcohol use disorder at some point in their lifetimes, including 17.8 percent with alcohol abuse and 12.5 percent with alcohol dependence, according to a report in the July issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

4 Jul 2007

Smokeless tobacco, good or bad?

Should the health community promote smokeless tobacco (snus) as a harm reduction measure?

4 Jul 2007

Study shows inaccuracies in cardiac PET-CT imaging

Current PET-CT scanners with standard commercial software designed to provide images of the heart are falsely indicating coronary artery disease in as many as 40 percent of patients, according to a study published today on the cover page of the Journal of Nuclear Medicine.

4 Jul 2007

Hearing loss and von Hippel-Lindau disease

Patients with the genetic disorder von Hippel-Lindau disease may suddenly experience hearing loss because of a tumor-associated hemorrhage in the inner ear, according to a study in the July 4 issue of JAMA.

4 Jul 2007

Antidepressants not linked to birth defects

Two research studies published in The New England Journal of Medicine found taking SSRIs (selective serotonin reuptake inhibitors), anti-depression drugs, during pregnancy did not significantly increase the overall risk for most birth defects.

4 Jul 2007

Risk-taking in infertility treatment correlates with women's negative moods

A study of women's moods during IVF has found a strong relationship between negative mood and multiple embryo transfer, a scientist told the 23rd annual conference of the European Society of Human Reproduction and Embryology (Tuesday 3 July).

4 Jul 2007

People with narcolepsy have a high frequency of REM sleep without muscle atonia

Normal rapid eye movement (REM) sleep is characterized by tonic features, including cortical electroencephalogram (EEG) desynchronization and muscle atonia, as well as phasic events, including bursts of REM, phasic activities of both chin and limb electromyography (EMG), and cardiorespiratory variability.

4 Jul 2007

Just one smoke can lead to nicotine addiction

A new study published in the Archives of Pediatric and Adolescent Medicine shows that 10 percent of youth who become hooked on cigarettes are addicted within two days of first inhaling from a cigarette, and 25 percent are addicted within a month.

4 Jul 2007