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New universal flu vaccine moves to clinical trial phase and could be a reality soon

Alphabet’s venture arm called Google Ventures earlier is one of the supporters of a mega projects that is developing a vaccine for flu that is safe and effective. Vaccitech from United Kingdom is working towards development of the vaccine and Alphabet has shown its support by contributing $27.6 million in new funding. The funds would be used conduct clinical trials and try the new vaccine.

16 Jan 2018

FDA grants approval for first drug to treat inherited breast cancer

The U.S. Food and Drug Administration today expanded the approved use of Lynparza (olaparib tablets) to include the treatment of patients with certain types of breast cancer that have spread (metastasized) and whose tumors have a specific inherited (germline) genetic mutation, making it the first drug in its class (PARP inhibitor) approved to treat breast cancer, and it is the first time any drug has been approved to treat certain patients with metastatic breast cancer who have a "BRCA" gene mutation.

15 Jan 2018

U.S. FDA approves first drug for patients with germline BRCA-mutated metastatic breast cancer

AstraZeneca and Merck, known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration has approved LYNPARZA (olaparib) for use in patients with deleterious or suspected deleterious germline BRCA-mutated (gBRCAm), human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer who have been previously treated with chemotherapy in the neoadjuvant, adjuvant or metastatic setting.

12 Jan 2018

Exposure to estrogen-mimicking compounds may reverse effects of breast cancer treatment

Scientists from The Scripps Research Institute have discovered that two estrogen-mimicking compounds found in many foods appear to potently reverse the effects of palbociclib/letrozole, a popular drug combination for treating breast cancer.

12 Jan 2018

Genetic analysis can enhance outcomes of depression treatment

The failure of drugs such as SSRIs, used to treat depression, can be a result of genetic variations in patients.

12 Jan 2018

Patients with desmoplastic melanoma respond well to immunotherapy

Desmoplastic melanoma is a rare subtype of melanoma that is commonly found on sun-exposed areas, such as the head and neck, and usually seen in older patients.

11 Jan 2018

Increased rate of language delay in girls linked to acetaminophen use by mothers during pregnancy

In the first study of its kind, researchers from the Icahn School of Medicine at Mount Sinai found an elevated rate of language delay in girls at 30 months old born to mothers who used acetaminophen during pregnancy, but not in boys.

10 Jan 2018

Novel antibiotic microspheres kill infections after joint replacement

More than 1 million people undergo total joint replacements each year, and nearly 10,000 will develop infections. To reduce this infection risk, a Houston Methodist orthopedic surgeon created small antibiotic beads that are implanted with the new joint to slowly release medicine for several weeks.

10 Jan 2018

Alzheimer’s Research UK calls on pharma to continue supporting dementia research

Alzheimer’s Research UK is calling for a recommitment from pharmaceutical companies to continue efforts to fund research into dementia, the leading cause of death in the UK.

10 Jan 2018

Ostomy patients using new skin barrier product experience lower costs of care

Ostomy patients using a new type of skin barrier product--infused with ceramides that play an essential role in the normal barrier function of the skin--experience lower costs of care, according to a randomized trial published in the Journal of Wound, Ostomy and Continence Nursing, the official journal of the Wound, Ostomy and Continence Nurses Society. The journal is published by Wolters Kluwer.

9 Jan 2018

Researchers awarded grant to repurpose FDA-approved drugs for treating Alzheimer's patients

Researchers from Case Western Reserve University School of Medicine and collaborators have received a five-year, $2.8 million grant from the National Institute on Aging to identify FDA-approved medications that could be repurposed to treat Alzheimer's disease.

9 Jan 2018

HHS nominee vows to tackle high drug costs, despite his ties to industry

Senate Democrats on Tuesday pressed President Donald Trump's nominee for the top health post to explain how he would fight skyrocketing drug prices — demanding to know why they should trust him to lower costs since he did not do so while running a major pharmaceutical company.

9 Jan 2018

PolyU develops new method for quick authentication of Chinese herbal medicines

The Food Safety and Technology Research Centre under the Department of Applied Biology and Chemical Technology of The Hong Kong Polytechnic University has developed a new method for rapid authentication of Chinese herbal medicines, including Ganoderma (known as Lingzhi in Chinese), and Gastrodiae Rhizoma (known as Tianma in Chinese).

9 Jan 2018

Pharmaceutical pollution can make aquatic microbial communities resistant to drugs

In urban streams, persistent pharmaceutical pollution can cause aquatic microbial communities to become resistant to drugs. So reports a new study published today in the journal Ecosphere.

9 Jan 2018

Leukemia patients currently ineligible for targeted therapy may benefit from new drugs

Patients with an aggressive form of leukemia, currently ineligible for any type of targeted therapy, may in fact benefit from some of these new drugs, according to new research by Queen Mary University of London.

9 Jan 2018

Beta blockers may improve survival for melanoma patients

A common, inexpensive drug that is used to prevent heart attacks and lower blood pressure may also help melanoma patients live longer, according to researchers.

8 Jan 2018

An opioid remedy that works: Treat pain and addiction at the same time

Seven years ago, Robert Kerley, who makes his living as a truck driver, was loading drywall when a gust of wind knocked him off the trailer. Kerley fell 14 feet and hurt his back.

8 Jan 2018

Drug overdose deaths soar nationally but plateau in some Western states

The opioid crisis on the East Coast and in the Midwest has fueled a national surge in drug deaths, even as fatal overdoses have decreased or remained stable in parts of the West, new federal data show.

8 Jan 2018

Sangamo and Pfizer partner for development of new zinc finger protein gene therapy to treat ALS

Sangamo Therapeutics, Inc. and Pfizer Inc. today announced a collaboration for the development of a potential gene therapy using zinc finger protein transcription factors (ZFP-TFs) to treat amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) linked to mutations of the C9ORF72 gene.

8 Jan 2018

Paracetamol use during pregnancy may impair fertility of female offspring

Taking paracetamol during pregnancy may impair the future fertility of female offspring, according to a review published in Endocrine Connections.

5 Jan 2018

Pharmaceutical News

New universal flu vaccine moves to clinical trial phase and could be a reality soon

FDA grants approval for first drug to treat inherited breast cancer

U.S. FDA approves first drug for patients with germline BRCA-mutated metastatic breast cancer

Exposure to estrogen-mimicking compounds may reverse effects of breast cancer treatment

Genetic analysis can enhance outcomes of depression treatment

Patients with desmoplastic melanoma respond well to immunotherapy

Increased rate of language delay in girls linked to acetaminophen use by mothers during pregnancy

Novel antibiotic microspheres kill infections after joint replacement

Alzheimer’s Research UK calls on pharma to continue supporting dementia research

Ostomy patients using new skin barrier product experience lower costs of care

Researchers awarded grant to repurpose FDA-approved drugs for treating Alzheimer's patients

HHS nominee vows to tackle high drug costs, despite his ties to industry

PolyU develops new method for quick authentication of Chinese herbal medicines

Pharmaceutical pollution can make aquatic microbial communities resistant to drugs

Leukemia patients currently ineligible for targeted therapy may benefit from new drugs

Beta blockers may improve survival for melanoma patients

An opioid remedy that works: Treat pain and addiction at the same time

Drug overdose deaths soar nationally but plateau in some Western states

Sangamo and Pfizer partner for development of new zinc finger protein gene therapy to treat ALS

Paracetamol use during pregnancy may impair fertility of female offspring

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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