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Hospitalizations for injection drug use-related infective endocarditis increasing among young Americans

Hospitalizations for infective endocarditis, a heart valve infection often attributed to injection drug use, have increased significantly among young adult Americans--particularly in whites and females--according to a new study by researchers from Tufts Medical Center and Tufts University School of Medicine.

1 Sep 2016

Taking two new epilepsy drugs during pregnancy may not harm thinking skills and IQs of children

Two epilepsy drugs, levetiracetam and topiramate, may not harm the thinking skills and IQs of school-age children born to women who took them while pregnant, according to a recent study.

1 Sep 2016

Combination drug therapy safe, effective in treating asthma patients

A post-marketing safety study mandated by the U.S. Food and Drug Administration has shown that a combination drug therapy for the treatment of asthma is safe and effective.

1 Sep 2016

WSU pharmacologists find hyperbaric oxygen therapy can alleviate opiate withdrawal symptoms

Washington State University researchers have found that treatments of pure oxygen in a high-pressure chamber can relieve the symptoms of opiate withdrawal.

31 Aug 2016

Solution made of silver nanoparticles shows promise in healing diabetic foot ulcers

One of the major complications of diabetes is the appearance of wounds in the lower extremities that do not heal properly.

31 Aug 2016

Researchers identify promising new drug treatment for cocaine addiction

A team of researchers led by Cardiff University has discovered a promising new drug treatment for cocaine addiction.

31 Aug 2016

Researchers working to find faster way to treat sleeping sickness using oral drugs

Researchers at the University of Georgia are working to find the fastest way possible to treat and cure human African trypanosomiasis, long referred to as sleeping sickness. By working to improve chemical entities already tested in human clinical trials, they hope to have a faster route to field studies to treat the disease using drugs that can be administered orally to patients.

30 Aug 2016

REVERSE II trial validates HERDOO2 rule to help spot women who can discontinue anticoagulants

A clinical decision rule (CDR) that can be applied to women after a first, unprovoked venous thromboembolism (VTE) was able to identify those with a low-risk of recurrence who could safely discontinue anticoagulant therapy, researchers reported at ESC Congress 2016.

30 Aug 2016

Experimental drug may become key tool to target triple-negative breast cancer with immunotherapy

Previous studies at the University of Colorado Cancer Center show that the experimental drug AMPI-109 potently kills triple-negative breast cancer cells.

30 Aug 2016

New anticoagulant treatment safe and effective for AF patients before cardioversion

Patients with atrial fibrillation (AF) who need anticoagulation before undergoing electrical correction of their abnormal heartbeat (cardioversion) may benefit from treatment with edoxoban - a non-vitamin K antagonist (VKA) oral anticoagulant (NOAC), according to results of the ENSURE-AF trial.

30 Aug 2016

Novel drug delivery system may offer new hope for patients with rare fatal genetic disorder

Researchers at Oregon State University and other institutions have discovered a type of drug delivery system that may offer new hope for patients with a rare, ultimately fatal genetic disorder - and make what might become a terrible choice a little easier.

30 Aug 2016

Antipsychotic use linked to higher pneumonia risk in patients with Alzheimer's disease

Antipsychotic medications are associated with an increased risk of pneumonia in persons with Alzheimer's disease (AD), according to new research from the University of Eastern Finland.

30 Aug 2016

Novel antidote effective in quickly reversing acute anticoagulant-related bleeding

A specially designed antidote to reverse acute, potentially life-threatening anticoagulant-related bleeding worked quickly, and was well-tolerated according to interim results of the ongoing ANNEXA-4 study.

30 Aug 2016

Novel compound provides safe, effective pain relief with zero abuse potential in animal model

Since the isolation of morphine from opium in the 19th century, scientists have hoped to find a potent opioid analgesic that isn't addictive and doesn't cause respiratory arrest with increased doses.

30 Aug 2016

Nebivolol treatment may protect against antracycline-induced cardiotoxicity in breast cancer patients

Nebivolol prevents anthracycline-induced cardiotoxicity, according to research presented at ESC Congress 2016 today by Professor Mirela Cleopatra Tomescu, a cardiologist at Victor Babes University of Medicine and Pharmacy, Timisoara, Romania.

30 Aug 2016

Gentle combination of FDA-approved drugs could combat photoreceptor degeneration in mice

In microseconds, every light ray that enters the eye triggers an explosion of coordinated cellular events.

29 Aug 2016

Platelet function testing in elderly patients after heart attack shows no improved outcomes

Monitoring platelet function in order to individualize antiplatelet therapy did not improve outcomes for elderly patients after a heart attack compared to a standard, unmonitored approach, results of the ANTARCTIC trial show.

29 Aug 2016

PCSK9 inhibitor can reduce need for apheresis treatment in patients with familial hypercholesterolemia

Patients who have heterozygous familial hypercholesterolemia (HeFH), a condition that causes abnormally raised low-density lipoprotein cholesterol (LDL-C) levels and premature cardiovascular disease, can significantly reduce or even eliminate their need for expensive and time-consuming apheresis treatments with the PCSK9 inhibitor alirocumab.

29 Aug 2016

Janssen seeks to extend DARZALEX license to benefit more multiple myeloma patients

Janssen-Cilag International NV has announced the submission of a Type II variation application to the European Medicines Agency (EMA), seeking to broaden the existing marketing authorisation for the immunotherapy DARZALEX® (daratumumab) to include treatment of adult patients with relapsed multiple myeloma who have received at least one prior therapy. The expanded indication is based on daratumumab in combination with lenalidomide (an immmunomodulatory agent) and dexamethasone, or bortezomib (a PI) and dexamethasone.

29 Aug 2016

New oral anticoagulants offer same stroke prevention, but cause less intracranial bleeding than warfarin

The new oral anticoagulants provide the same stroke prevention as warfarin but cause less intracranial bleeding, reports an observational study in more than 43 000 patients presented at ESC Congress 2016 today by Dr Laila Staerk, a research fellow at Herlev and Gentofte University Hospital, Denmark.

28 Aug 2016

Pharmaceutical News

Hospitalizations for injection drug use-related infective endocarditis increasing among young Americans

Taking two new epilepsy drugs during pregnancy may not harm thinking skills and IQs of children

Combination drug therapy safe, effective in treating asthma patients

WSU pharmacologists find hyperbaric oxygen therapy can alleviate opiate withdrawal symptoms

Solution made of silver nanoparticles shows promise in healing diabetic foot ulcers

Researchers identify promising new drug treatment for cocaine addiction

Researchers working to find faster way to treat sleeping sickness using oral drugs

REVERSE II trial validates HERDOO2 rule to help spot women who can discontinue anticoagulants

Experimental drug may become key tool to target triple-negative breast cancer with immunotherapy

New anticoagulant treatment safe and effective for AF patients before cardioversion

Novel drug delivery system may offer new hope for patients with rare fatal genetic disorder

Antipsychotic use linked to higher pneumonia risk in patients with Alzheimer's disease

Novel antidote effective in quickly reversing acute anticoagulant-related bleeding

Novel compound provides safe, effective pain relief with zero abuse potential in animal model

Nebivolol treatment may protect against antracycline-induced cardiotoxicity in breast cancer patients

Gentle combination of FDA-approved drugs could combat photoreceptor degeneration in mice

Platelet function testing in elderly patients after heart attack shows no improved outcomes

PCSK9 inhibitor can reduce need for apheresis treatment in patients with familial hypercholesterolemia

Janssen seeks to extend DARZALEX license to benefit more multiple myeloma patients

New oral anticoagulants offer same stroke prevention, but cause less intracranial bleeding than warfarin

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