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Research findings open avenues for creating new classes of anticancer drugs

A new study at Los Alamos National Laboratory and in collaboration with Stanford Synchrotron Radiation Lightsource greatly improves scientists' understanding of the element actinium. The insights could support innovation in creating new classes of anticancer drugs.

18 Aug 2016

New book from Cold Spring Harbor examines major antibiotics and mechanisms of resistance

One of the greatest medical accomplishments of the past century was the introduction of antibiotics into the clinic.

18 Aug 2016

Low adherence to antipsychotic medication linked to long-term homelessness

SFU health sciences researcher Stefanie Rezansoff has published a new study on the treatment of serious mental illnesses among people who are homeless. This is the first study to investigate adherence to antipsychotic medication in this population.

18 Aug 2016

T-sol can be safe and effective treatment for men with hypogonadism

For men with hypogonadism, a condition in which the body does not produce enough testosterone, low sex drive and fatigue are common symptoms.

17 Aug 2016

Steroid treatment linked to increased risk of retinopathy in very low birth weight infants

Because of the beneficial effect of corticosteroids on lung function, especially in infants who are ventilator dependent, corticosteroids are, at times, administered to very low birth weight neonates to treat established or evolving lung disease. However, it has long been suspected that steroids may have negative neurodevelopmental effects on very premature infants.

16 Aug 2016

New guidance provides effective practices for prehospital use of TXA in injured patients

Tranexamic acid (TXA) is currently being administered to injured patients by many prehospital air and ground systems, despite a lack of evidence supporting or refuting its efficacy in preventing hemorrhage.

16 Aug 2016

NIH funds collaborative project to develop better vaccine adjuvants for many diseases

Dr. Qizhi Cathy Yao, professor of surgery, molecular virology and microbiology, and pathology & immunology at Baylor College of Medicine, has been awarded a National Institutes of Health grant to fund a collaborative project with Molecular Express, Inc.

12 Aug 2016

Intestinal flora likely to have effect on person's response to drugs

Intestinal flora has multiple influences on human health, but researchers have revealed that it is also likely to have an effect on the body's response to drugs.

12 Aug 2016

RACP releases new Choosing Wisely Australia recommendations on appropriate use of medicines for older adults

The latest lists developed by specialties from the Royal Australasian College of Physicians as part of the Choosing Wisely Australia initiative deliver a strong message on appropriate use of medicines for older Australians.

12 Aug 2016

EPFL scientists develop new method to cheaply produce chemical compounds

EPFL scientists design a new method to cheaply produce some of the most important chemical compounds in the pharmaceutical industry - the amines.

12 Aug 2016

FDA grants Orphan Drug Designation to CD4CAR therapy for treatment of peripheral T-cell lymphoma

iCell Gene Therapeutics today (Aug. 11) announced that the Food and Drug Administration has granted Orphan Drug Designation for its chimeric antigen receptor engineered T-cells directed against the target protein CD4 (CD4CAR) for the treatment of peripheral T-cell lymphoma (PTCL).

12 Aug 2016

Specific molecular features control uptake of biguanides into mitochondria to inhibit respiration

The biguanides are a family of drugs with diverse clinical applications. Metformin, a widely used anti-hyperglycemic biguanide, suppresses mitochondrial respiration by inhibiting respiratory complex I. Phenformin, a related anti-hyperglycemic biguanide, also inhibits respiration, but proguanil, which is widely used for the prevention of malaria, does not.

12 Aug 2016

Opioid naive individuals at low risk of developing persistent opioid use after surgery, research shows

Researchers from the University Health Network's Department of Anesthesia and Pain Management and the Institute for Clinical Evaluative Sciences have determined that patients who have not had an opioid prescription within a year prior to their procedure are at low risk of developing persistent opioid use after major surgery.

11 Aug 2016

Scientists identify potential mechanism that paves way for improved treatment of fungal infections

By identifying new compounds that selectively block mitochondrial respiration in pathogenic fungi, Whitehead Institute scientists have identified a potential antifungal mechanism that could enable combination therapy with fluconazole, one of today's most commonly prescribed fungal infection treatments.

11 Aug 2016

Research finding opens new avenues to tailor drug development with Upsalite

For the first time, researchers have revealed the nanostructure of the mesoporous magnesium carbonate Upsalite and pore size control was achieved without organic templates or swelling agents.

11 Aug 2016

Researchers uncover one way breast cancer tumors resist vital medication

A team of Case Western Reserve University School of Medicine cancer researchers has uncovered one way certain tumors resist vital medication.

11 Aug 2016

First investigational treatment for infantile-onset SMA shows promising results in clinical trial

A major milestone was reached when nusinersen, an investigational treatment for spinal muscular atrophy (SMA), was shown to significantly improve achievement of motor milestones in babies with infantile-onset SMA, according to an interim analysis of the double-blind, randomized, placebo controlled Phase 3 clinical trial called ENDEAR.

11 Aug 2016

Pharmaceutical News

Research findings open avenues for creating new classes of anticancer drugs

New book from Cold Spring Harbor examines major antibiotics and mechanisms of resistance

Low adherence to antipsychotic medication linked to long-term homelessness

T-sol can be safe and effective treatment for men with hypogonadism

Steroid treatment linked to increased risk of retinopathy in very low birth weight infants

New guidance provides effective practices for prehospital use of TXA in injured patients

NIH funds collaborative project to develop better vaccine adjuvants for many diseases

Intestinal flora likely to have effect on person's response to drugs

RACP releases new Choosing Wisely Australia recommendations on appropriate use of medicines for older adults

EPFL scientists develop new method to cheaply produce chemical compounds

FDA grants Orphan Drug Designation to CD4CAR therapy for treatment of peripheral T-cell lymphoma

Specific molecular features control uptake of biguanides into mitochondria to inhibit respiration

Opioid naive individuals at low risk of developing persistent opioid use after surgery, research shows

Scientists identify potential mechanism that paves way for improved treatment of fungal infections

Research finding opens new avenues to tailor drug development with Upsalite

Researchers uncover one way breast cancer tumors resist vital medication

First investigational treatment for infantile-onset SMA shows promising results in clinical trial

New drug provides considerable added benefit in treating adults with advanced renal cell cancer

Commonly used anti-inflammatory drug shows potential to treat Alzheimer's disease

Drug approved for treatment of vulvovaginal atrophy shows no added benefit in post-menopausal women

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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