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Scientists develop model using transformed stem cells to accelerate screening of drugs for rare cancers

Researchers at the Johns Hopkins Kimmel Cancer Center say they have developed a system that uses transformed human stem cells to speed up screening of existing drugs that might work against rare brain and other cancers.

2 Aug 2016

Generic biologic drugs appear to be as effective as brand-name versions

Generic forms of a biologic drug used to treat rheumatoid arthritis, inflammatory bowel disease and psoriasis appear to be as safe and effective as their brand-name counterparts, a new Johns Hopkins Bloomberg School of Public Health analysis suggests.

2 Aug 2016

Iron-containing catalysts can alter amino acids to help develop new drug candidates

For medicinal chemists, making tweaks to peptide structures is key to developing new drug candidates. Now, researchers have demonstrated that two iron-containing small-molecule catalysts can help turn certain types of amino acids -- the building blocks of peptides and proteins -- into an array of potential new forms, even when part of a larger peptide, while preserving a crucial aspect of their chemistry: chirality, or "handedness."

2 Aug 2016

Erectile dysfunction drugs do not play role in preventing prostate cancer, study shows

While some previous studies have indicated that taking erectile dysfunction (ED) drugs may reduce the likelihood of developing prostate cancer, new research published in The Journal of Urology found that these drugs do not play a role in preventing prostate cancer.

2 Aug 2016

New review examines potential of antioxidant therapies to combat neurodegenerative disorders

A new review examines the potential of antioxidant approaches for the treatment of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, and multiple sclerosis.

2 Aug 2016

Early initiation of antiretroviral therapy can considerably reduce total HIV DNA levels

A team of researchers, led by Drs. Merlin Robb and Jintanat Ananworanich of the U.S. Military HIV Research Program at the Walter Reed Army Institute of Research, has found that when antiretroviral therapy (ART) is initiated during early acute HIV infection, it can significantly reduce total HIV DNA levels in the body, which may have implications for the goal of achieving long-term HIV remission.

2 Aug 2016

New research opens door to influencing immune system

A new international collaboration involving scientists at The Scripps Research Institute opens a door to influencing the immune system, which would be useful to boost the effectiveness of vaccines or to counter autoimmune diseases such as lupus and rheumatoid arthritis.

2 Aug 2016

New drug prevents vaginal and oral transmission of HIV in pre-clinical animal models

HIV remains a major health concern for women and children globally. Worldwide, the majority of new HIV infections occur in young women. Each year, 1.5 million women living with HIV become pregnant.

2 Aug 2016

Chemists develop faster, cheaper method to quantify water content in solid pharmaceutical drugs

Chemists at The University of Texas at Arlington have invented a method to quantify water content in solid pharmaceutical drugs that is faster, cheaper, more accurate and more precise than Karl Fischer titration, the method currently recognized by the U.S. Food and Drug Administration and widely used worldwide.

1 Aug 2016

New report urges all European countries to adopt universal vaccination for hepatitis

To coincide with World Hepatitis Day, a new report, commissioned by United European Gastroenterology, calls for all European countries to adopt universal vaccination and harmonised screening programmes for hepatitis, as well as improved neonatal screening, to help speed up the eradication of the disease.

1 Aug 2016

Combined therapy may lead to better outcomes in children with ADHD

Three studies to be published in the August 2016 issue of the Journal of the American Academy of Child and Adolescent Psychiatry report that combining two standard medications could lead to greater clinical improvements for children with attention-deficit/hyperactivity disorder (ADHD) than either ADHD therapy alone.

1 Aug 2016

NABP report points rogue internet drug outlets serve as dealers to people purchasing controlled substances

Today, the National Association of Boards of Pharmacy (NABP) released its Internet Drug Outlet Identification Program Progress Report for State and Federal Regulators: July 2016.

30 Jul 2016

Lisinopril oral solution approved for treatment of hypertension in children and adults

Silvergate Pharmaceuticals, Inc., leader in the development and commercialization of innovative and safe medicines for children, today announced that the United States Food and Drug Administration approved Qbrelis (Lisinopril) Oral Solution, the first and only FDA-approved Lisinopril oral solution.

30 Jul 2016

Kaiser Permanente telestroke program increases use of clot-dissolving treatment for stroke patients

The use of a life-saving clot-dissolving treatment for patients with acute ischemic stroke increased by 73 percent following the implementation of a Kaiser Permanente telestroke program, according to a study published today in The Permanente Journal.

30 Jul 2016

CVS Health to make opioid overdose-reversing drug more affordable for patients without insurance

CVS Health and Adapt Pharma today announced a new partnership that will make the opioid overdose-reversing drug NARCAN (Naloxone HCl) Nasal Spray more affordable for patients without insurance at CVS Pharmacy locations.

30 Jul 2016

USPTO grants key patent for Quark Pharmaceuticals' QPI-1007 ocular neuroprotectant

Quark Pharmaceuticals, Inc. today announced that the United States Patent and Trademark Office has granted a key patent covering the treatment of patients suffering from non-arteritic anterior ischemic optic neuropathy ("NAION") with the Company's ocular neuroprotectant QPI-1007.

30 Jul 2016

Researchers identify key immune differences that could help in development of effective HIV vaccine

One of the main mysteries confounding development of an HIV vaccine is why some people infected with the virus make the desired antibodies after several years, but a vaccine can't seem to induce the same response.

30 Jul 2016

Vaccination against single strain could confer protection against diverse Zika virus infections

Vaccination against a single strain of Zika virus should be sufficient to protect against genetically diverse strains of the virus, according to a study conducted by investigators from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health; Washington University in St. Louis; and Emory University in Atlanta.

29 Jul 2016

University of Utah investigators receive $25 million grant to improve clinical research

Investigators at the University of Utah School of Medicine's Data Coordinating Center have been awarded a seven-year, $25 million grant from the National Center for Advancing Translational Sciences of the National Institutes of Health, to form one of three Trial Innovation Centers to improve clinical research.

29 Jul 2016

Convenience of buying medicine online does not outweigh risks, says expert

With the rise of on-demand delivery, prescription medicine joins the countless list of items that can be ordered online with the click of a button.

29 Jul 2016

Pharmaceutical News

Scientists develop model using transformed stem cells to accelerate screening of drugs for rare cancers

Generic biologic drugs appear to be as effective as brand-name versions

Iron-containing catalysts can alter amino acids to help develop new drug candidates

Erectile dysfunction drugs do not play role in preventing prostate cancer, study shows

New review examines potential of antioxidant therapies to combat neurodegenerative disorders

Early initiation of antiretroviral therapy can considerably reduce total HIV DNA levels

New research opens door to influencing immune system

New drug prevents vaginal and oral transmission of HIV in pre-clinical animal models

Chemists develop faster, cheaper method to quantify water content in solid pharmaceutical drugs

New report urges all European countries to adopt universal vaccination for hepatitis

Combined therapy may lead to better outcomes in children with ADHD

NABP report points rogue internet drug outlets serve as dealers to people purchasing controlled substances

Lisinopril oral solution approved for treatment of hypertension in children and adults

Kaiser Permanente telestroke program increases use of clot-dissolving treatment for stroke patients

CVS Health to make opioid overdose-reversing drug more affordable for patients without insurance

USPTO grants key patent for Quark Pharmaceuticals' QPI-1007 ocular neuroprotectant

Researchers identify key immune differences that could help in development of effective HIV vaccine

Vaccination against single strain could confer protection against diverse Zika virus infections

University of Utah investigators receive $25 million grant to improve clinical research

Convenience of buying medicine online does not outweigh risks, says expert

PhD researcher at LifeArc

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