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FDA approves safety labeling changes for fluoroquinolone antibiotics

The U.S. Food and Drug Administration today approved safety labeling changes for a class of antibiotics, called fluoroquinolones, to enhance warnings about their association with disabling and potentially permanent side effects and to limit their use in patients with less serious bacterial infections.

27 Jul 2016

Penn researchers use iron-containing nanoparticles to reduce plaque and prevent tooth decay

The bacteria that live in dental plaque and contribute to tooth decay often resist traditional antimicrobial treatment, as they can "hide" within a sticky biofilm matrix, a glue-like polymer scaffold.

26 Jul 2016

Study shows drugs for hypertension may help treat mood disorders

In the current issue of Psychotherapy and Psychosomatics, the relationship of drugs that are generally used for treating hypertension (angiotensin converting enzyme inhibitors) are examined in their effects as to depression.

26 Jul 2016

Novel community-produced biological network models hold potential in drug discovery and toxicology

A new set of community-produced biological network models has been shown to allow a deeper understanding of the mechanisms underlying a range of diseases.

26 Jul 2016

Study identifies key risk factors involved in patient-to-patient transmission of drug-resistant bacteria

Three key factors increase the risk for patient-to-patient transmission of an extremely drug-resistant bacteria known as CP-CRE, according to a new study published today in Infection Control & Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

26 Jul 2016

Hematology researchers develop new bio-engineered clotting factor to control bleeding

Every five minutes someone in the U.S. dies from a blood clot, through its role in strokes, heart attacks or other severe conditions.

26 Jul 2016

Common drug for type 2 diabetes may play surprising role in preventing preterm birth

Metformin, a medication routinely used by millions of people with type 2 diabetes, may also play an unexpected role in blocking a significant cause of preterm birth, according to research findings published July 25.

26 Jul 2016

Promising new therapeutic target could lead to better prognosis of spinal muscular atrophy

According to studies, approximately one out of every 40 individuals in the United States is a carrier of the gene responsible for spinal muscular atrophy (SMA), a neurodegenerative disease that causes muscles to weaken over time.

25 Jul 2016

Adhesive patch can deliver triple combination therapy to tumor sites

Approximately one in 20 people will develop colorectal cancer in their lifetime, making it the third-most prevalent form of the disease in the U.S. In Europe, it is the second-most common form of cancer.

25 Jul 2016

Achilles' heel of malaria parasite could be exploited to treat deadly disease

Malaria researchers at The Australian National University have found one of the malaria parasite's best weapons against drug treatments turns out to be an Achilles' heel, which could be exploited to cure the deadly disease.

25 Jul 2016

New study aims to identify ways of helping patients withdraw from long-term antidepressant treatment

One in 10 adults are being given antidepressants each year, but up to 50 per cent of patients could be given an alternative treatment, a University Professor suggests.

25 Jul 2016

Researchers develop new microneedle system to painlessly monitor drugs in bloodstream

Researchers at the University of British Columbia and the Paul Scherrer Institut in Switzerland have created a microneedle drug monitoring system that could one day replace costly, invasive blood draws and improve patient comfort.

25 Jul 2016

Combination of two plant compounds holds promise in treating colon cancer

The combination of two plant compounds that have medicinal properties - curcumin and silymarin - holds promise in treating colon cancer, according Saint Louis University research published in the June 23 issue of the Journal of Cancer.

22 Jul 2016

Study uncovers new drug-gene mutation combinations that can kill cancer cells

In an effort to expand the number of cancer gene mutations that can be specifically targeted with personalized therapies, researchers at University of California San Diego School of Medicine and Moores Cancer Center looked for combinations of mutated genes and drugs that together kill cancer cells.

22 Jul 2016

New on-line resource allows user to virtually test effectiveness, specificity of potential drug

Inside the human body, the same drug can interact with multiple molecules. This phenomenon is known as 'polypharmacology' and, according to the interaction, a drug can cure a disease or cause side effects in the patient.

22 Jul 2016

Combinations of three antibiotics could help combat drug-resistant bacterial infections

Each year, approximately 700,000 people die from drug-resistant bacterial infections. A study by UCLA life scientists could be a major step toward combating drug-resistant infections.

22 Jul 2016

Scientist develops new method for identifying proteins to build new biologics

A University of Toronto scientist has developed a new method for identifying the raw ingredients necessary to build 'biologics', a powerful class of medications that has revolutionized treatment of diseases like rheumatoid arthritis and some cancers.

22 Jul 2016

New neuroprotective compounds may prevent development of epilepsy

A team led by Nicolas Bazan, MD, PhD, Boyd Professor and Director of LSU Health New Orleans' Neuroscience Center of Excellence, has developed neuroprotective compounds that may prevent the development of epilepsy.

22 Jul 2016

Scientists design and construct 10 large protein icosahedra to improve drug delivery

Using novel computational and biochemical approaches, scientists have accurately designed and built from scratch 10 large protein icosahedra--polyhedra with 20 faces--similar to viral capsids that carry viral DNA.

22 Jul 2016

Adults with pain could be at higher risk of developing prescription opioid use disorders

What do we really know about the relationship between the experience of pain and risk of developing opioid use disorder? Results from a recent study - the first to directly address this question -- show that people with moderate or more severe pain had a 41 percent higher risk of developing prescription opioid use disorders than those without, independent of other demographic and clinical factors.

22 Jul 2016

Pharmaceutical News

FDA approves safety labeling changes for fluoroquinolone antibiotics

Penn researchers use iron-containing nanoparticles to reduce plaque and prevent tooth decay

Study shows drugs for hypertension may help treat mood disorders

Novel community-produced biological network models hold potential in drug discovery and toxicology

Study identifies key risk factors involved in patient-to-patient transmission of drug-resistant bacteria

Hematology researchers develop new bio-engineered clotting factor to control bleeding

Common drug for type 2 diabetes may play surprising role in preventing preterm birth

Promising new therapeutic target could lead to better prognosis of spinal muscular atrophy

Adhesive patch can deliver triple combination therapy to tumor sites

Achilles' heel of malaria parasite could be exploited to treat deadly disease

New study aims to identify ways of helping patients withdraw from long-term antidepressant treatment

Researchers develop new microneedle system to painlessly monitor drugs in bloodstream

Combination of two plant compounds holds promise in treating colon cancer

Study uncovers new drug-gene mutation combinations that can kill cancer cells

New on-line resource allows user to virtually test effectiveness, specificity of potential drug

Combinations of three antibiotics could help combat drug-resistant bacterial infections

Scientist develops new method for identifying proteins to build new biologics

New neuroprotective compounds may prevent development of epilepsy

Scientists design and construct 10 large protein icosahedra to improve drug delivery

Adults with pain could be at higher risk of developing prescription opioid use disorders

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