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European Union may be catching up to the United States in nonmedical prescription drug abuse

There is a high rate of prescription pain reliever abuse in Europe, largely accounted by opioids, according to the first comparative study of prescription drug abuse in the European Union, which was conducted by researchers at RTI International and published in BMC Psychiatry.

5 Aug 2016

Botulinum toxins may cause remote effects by moving between neurons

The botulinum toxins are among the deadliest substances on Earth, and two specific toxins — including the popular drug Botox — have multiple uses for treating many neuromuscular conditions, including frown lines, disabling muscle spasms and migraine headaches.

5 Aug 2016

Penn researchers develop computer model for designing drug-delivery nanocarriers

A team of University of Pennsylvania researchers has developed a computer model that will aid in the design of nanocarriers, microscopic structures used to guide drugs to their targets in the body.

5 Aug 2016

Three vaccine candidates provide complete protection against Zika virus in rhesus monkeys

A month after announcing that two promising vaccine candidates provided mice with complete protection against the Zika virus, a research team at Beth Israel Deaconess Medical Center, in collaboration with scientists at Walter Reed Army Institute of Research and the University of São Paulo, now reports achieving complete protection against Zika virus in rhesus monkeys.

5 Aug 2016

Triple therapy approach helps Type 1 diabetes patients improve blood sugar control, lose weight

A combination of three medications—dapagliflozin, liraglutide and insulin—helped people with Type 1 diabetes improve blood sugar control and lose weight, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

5 Aug 2016

Women using contraception containing estrogen may have high vitamin D levels, study shows

Women risk having their vitamin D levels fall when they stop using birth control pills or other contraceptives containing estrogen, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

4 Aug 2016

Research shows alcohol abuse drug inhibits ocular conjunctival scarring in mouse model

New research from University College London, Moorfields Eye Hospital and Duke University School of Medicine has identified a gene that drives scarring, together with a rapidly translatable therapy, for the UK's most common cause of blinding conjunctivitis.

4 Aug 2016

Researchers report promising vaccine strategy for immunizing against herpes viruses

Oral and genital herpes are caused by the herpes simplex virus type 1 (HSV-1) and the herpes simplex virus type 2 (HSV-2), which both cause lifelong infection. HSV-2 infection is associated with increased risk for HIV infection.

4 Aug 2016

Some WADA-banned substances may have potential medical applications

As the world awaits the start of the 2016 Summer Olympics, doping in athletes remains a hot topic.

4 Aug 2016

Combinations of FDA-approved drugs may prevent vision loss linked to retinal degeneration

Combinations of Food and Drug Administration-approved drugs protect against the loss of cells required for vision in a mouse model of blinding retinal diseases.

4 Aug 2016

Study finds high rate of misuse of seizure and pain drug

With increasing public attention to overdose deaths and misuse of prescription medications in the United States, researchers today presented the results of a new study looking at abuse and misuse of gabapentin, a medication used to treat seizures and relieve nerve pain often associated with shingles.

3 Aug 2016

New drug treatment could reduce body weight in obese patients with rare genetic disorder

As part of a phase II study at Charité - Universitätsmedizin Berlin and the Berlin Institute of Health, two obese patients with a rare genetic disorder were given a drug treatment to stimulate the satiety center in the brain.

3 Aug 2016

Neurologists identify cause of immune-mediated neuropathies

Würzburg neurologists have discovered an antibody that is involved in triggering certain forms of neuropathies. This discovery also allowed them to show a way to treat these diseases successfully.

3 Aug 2016

Research paves way for development of new drugs to prevent cancer and Alzheimer's

A new generation of drugs that prevent cancer and Alzheimer's could be developed, thanks to research from the University of Warwick.

3 Aug 2016

PD-1-responsive T cells may offer clues to design more effective drugs for cancer

Cancer immunotherapy drugs that block the inhibitory PD-1 pathway have shown success in clinical trials and are now FDA-approved for melanoma, lung cancer and bladder cancer. Yet many patients' tumors do not respond to these drugs.

3 Aug 2016

Metabolic-checkpoint inhibitor combination approach may improve cancer therapies

Reprogramming of the molecular pathways underlying normal metabolism is essential for T cell infection-fighting function and for the immune system to form a "memory" of the microbes it has already encountered. But exactly how metabolism in exhausted T cells is maintained in chronic infections and cancer is a missing element in this line of research.

3 Aug 2016

Research shows pharmacy access can help people from going back to hospital

Hospital readmissions, a $17 billion annual problem, are higher in rural, remote or smaller communities that sometimes have significantly less access to pharmacies, according to a study published today that was one of the first to examine this issue.

2 Aug 2016

Study shows diabetes drug ineffective in improving condition of patients with advanced heart failure

In an attempt to correct defects in the energy generation that contribute to poor pump function among heart failure patients, researchers examined whether the diabetes drug liraglutide, could improve the condition of patients with advanced heart failure.

2 Aug 2016

Griffith University to collaborate with Olymvax for new vaccine technology that could benefit millions

Griffith University will partner with a Chinese pharmaceutical, Olymvax Biopharmaceuticals Inc. for a new vaccine that could benefit millions.

2 Aug 2016

Vaccines unsuccessful in protecting obese mice against influenza infections, study finds

A study led by St. Jude Children's Research Hospital found that obese mice are not protected against influenza infections by vaccines that include adjuvants, raising concerns about vaccine effectiveness in obese humans who are known to be at an increased risk for severe flu. The findings appear today in the scientific journal mBio.

2 Aug 2016

Pharmaceutical News

European Union may be catching up to the United States in nonmedical prescription drug abuse

Botulinum toxins may cause remote effects by moving between neurons

Penn researchers develop computer model for designing drug-delivery nanocarriers

Three vaccine candidates provide complete protection against Zika virus in rhesus monkeys

Triple therapy approach helps Type 1 diabetes patients improve blood sugar control, lose weight

Women using contraception containing estrogen may have high vitamin D levels, study shows

Research shows alcohol abuse drug inhibits ocular conjunctival scarring in mouse model

Researchers report promising vaccine strategy for immunizing against herpes viruses

Some WADA-banned substances may have potential medical applications

Combinations of FDA-approved drugs may prevent vision loss linked to retinal degeneration

Study finds high rate of misuse of seizure and pain drug

New drug treatment could reduce body weight in obese patients with rare genetic disorder

Neurologists identify cause of immune-mediated neuropathies

Research paves way for development of new drugs to prevent cancer and Alzheimer's

PD-1-responsive T cells may offer clues to design more effective drugs for cancer

Metabolic-checkpoint inhibitor combination approach may improve cancer therapies

Research shows pharmacy access can help people from going back to hospital

Study shows diabetes drug ineffective in improving condition of patients with advanced heart failure

Griffith University to collaborate with Olymvax for new vaccine technology that could benefit millions

Vaccines unsuccessful in protecting obese mice against influenza infections, study finds

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