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New type of HIV drug works in unusual way

A new type of HIV drug currently being tested works in an unusual way, scientists in the Molecular Medicine Partnership Unit, a collaboration between EMBL and Heidelberg University Hospital, have found.

17 Jul 2016

Duke University study provides new mechanistic understanding of OCD

A single chemical receptor in the brain is responsible for a range of symptoms in mice that are reminiscent of obsessive-compulsive disorder (OCD), according to a Duke University study that appears online in the journal Biological Psychiatry.

17 Jul 2016

Study finds sex differences in smoking cessation with medications

A new study led by Assistant Medical Professor Philip Smith of The City College of New York's Sophie Davis Biomedical Education/CUNY School of Medicine, and conducted in collaboration with researchers at Yale University and Yeshiva University, found important differences between women and men in their ability to quit smoking when taking medications commonly prescribed to help smokers quit.

17 Jul 2016

Study compares aripiprazole and quetiapine for treatment of schizophrenia

Schizophrenia is a common cause of incapacity and is ranked as the third-most-disabling illness subsequent to dementia and quadriplegia.

15 Jul 2016

Researchers propose new approach to target chemotherapy medications specifically to sarcomas

Sarcoma is an aggressive form of cancer responsible for up to 20 percent of childhood cancers. Tumors often first appear in the extremities and the abdomen. Surgery is a primary treatment, but it often is combined with chemotherapy.

15 Jul 2016

Novel method can test multi-drug resistant bacteria’s susceptibility to antibiotics in clinical setting

The recent emergence of bacterial infections that are resistant to many existing antibiotics is driving an urgent need for tools to quickly identify the small number of therapies that are still effective for individual patients.

15 Jul 2016

IDSA/ATS recommends shorter courses of antibiotics for patients with hospital-acquired, ventilator-associated pneumonia

Hospital-acquired pneumonia and ventilator-associated pneumonia– which account for 20 to 25 percent of hospital-acquired infections – should be treated with shorter courses of antibiotics than they typically are, according to new guidelines released by the Infectious Diseases Society of America and American Thoracic Society and published in the journal Clinical Infectious Diseases.

14 Jul 2016

Researchers identify new drug target for treating children with CNS-PNET

Primitive neuroectodermal tumors (PNETs) are the largest group of malignant brain tumors in children. They can arise from the brain's cerebellum or, more rarely, from tissue located throughout the central nervous system (CNS).

14 Jul 2016

Study finds low rates of baseline BMD testing among older women with breast cancer

Aromatase inhibitors (AIs)—drugs that stop the production of estrogen in women—are standard adjuvant therapy for post-menopausal women with hormone-receptor positive breast cancer.

14 Jul 2016

Combination approach could be more effective to treat fibromyalgia pain

Queen's University researcher Ian Gilron has uncovered a more effective way of treating fibromyalgia, a medical condition characterized by chronic widespread pain typically accompanied by fatigue, as well as sleep, mood and memory problems.

14 Jul 2016

Penn study provides more insights into cardiovascular side effects of breast cancer drug

A receptor protein that is the target of the breast cancer drug trastuzumab (Herceptin) is needed for proper heart blood-vessel development, reported researchers from the Perelman School of Medicine at the University of Pennsylvania.

14 Jul 2016

New opioid use among older adults with COPD linked to increased risk for respiratory-related death

Older adults with chronic obstructive pulmonary disease who start using opioids have a more than two-fold higher risk of dying from a respiratory-related complication compared to non-opioid users, St. Michael's Hospital researchers have found.

14 Jul 2016

New treatment approach may benefit relapsed post-transplant blood cancer patients

For many patients with advanced blood cancers, a stem-cell transplant can drive the disease into remission. However, about one-third of these patients experience a relapse and face a very poor prognosis.

13 Jul 2016

UCLA scientists identify mechanisms of tumor resistance to immunotherapy in advanced melanoma

UCLA researchers have for the first time identified mechanisms that determine how advanced melanoma can become resistant to immune checkpoint inhibitors, a discovery that could lead to the development of new and improved treatments for the deadliest type of skin cancer.

13 Jul 2016

Researchers receive grant to test transcutaneously refillable implant that delivers HIV-prevention drugs

A Houston Methodist research team received a nearly $4 million grant to test a transcutaneously refillable implant that administers pre-exposure prophylaxis drugs to subjects at risk of HIV-exposure.

13 Jul 2016

Policies restricting opioid prescriptions could harm pain patients, suggests review

A recent review and analysis suggests that some policies restricting opioid prescriptions to curb overdose deaths could be harming those who need them the most: pain patients.

13 Jul 2016

Immunotherapy drug combination shows prominent therapeutic effect against advanced and metastatic cancers in mice

A drug combination designed to enhance the immune system's ability to zero in and attack cancer cells has shown a pronounced therapeutic effect against advanced and metastatic cancers in mice, according to a Mayo Clinic study, published in the July 12 edition of the online journal Oncotarget.

12 Jul 2016

Pharmaceutical News

New type of HIV drug works in unusual way

Duke University study provides new mechanistic understanding of OCD

Study finds sex differences in smoking cessation with medications

Study compares aripiprazole and quetiapine for treatment of schizophrenia

Researchers propose new approach to target chemotherapy medications specifically to sarcomas

Novel method can test multi-drug resistant bacteria’s susceptibility to antibiotics in clinical setting

IDSA/ATS recommends shorter courses of antibiotics for patients with hospital-acquired, ventilator-associated pneumonia

Researchers identify new drug target for treating children with CNS-PNET

Study finds low rates of baseline BMD testing among older women with breast cancer

Combination approach could be more effective to treat fibromyalgia pain

Penn study provides more insights into cardiovascular side effects of breast cancer drug

New opioid use among older adults with COPD linked to increased risk for respiratory-related death

New treatment approach may benefit relapsed post-transplant blood cancer patients

UCLA scientists identify mechanisms of tumor resistance to immunotherapy in advanced melanoma

Researchers receive grant to test transcutaneously refillable implant that delivers HIV-prevention drugs

Policies restricting opioid prescriptions could harm pain patients, suggests review

Immunotherapy drug combination shows prominent therapeutic effect against advanced and metastatic cancers in mice

Scientists reveal how manipulating novel target in the brain could lead to new therapies for depression

Researchers make successful vaccine formulation that targets proteins linked to Alzheimer’s disease

CNIO study shows proinflammatory molecule IL-17A can be key factor in development of NASH and HCC

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