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Texas Biomed scientists receive $23 million NIH grant to develop AIDS vaccine

To support a coordinated, innovative approach to the development of an AIDS vaccine, Texas Biomedical Research Institute scientists, together with a multi-institutional coalition of experts from the United States and Europe, have received a grant for $23 million from the National Institute of Allergy and Infectious Diseases of the National Institutes of Health.

22 Jul 2016

Patients with cLBP more likely to use illicit drugs, study reports

People living with chronic low back pain (cLBP) are more likely to use illicit drugs -- including marijuana, cocaine, heroin, and methamphetamine -- compared to those without back pain, reports a study in Spine, published by Wolters Kluwer.

21 Jul 2016

BET inhibitor treatment decreases lung inflammation in mice

Patients with cystic fibrosis (CF) suffer from chronic respiratory infections, primarily caused by Pseudomonas aeruginosa, which lead to airway inflammation and damage.

21 Jul 2016

Neutrons key to discovering new HIV drugs? An interview with Dr Matthew Blakeley

Neutron crystallography allows us to determine the three-dimensional structures of biological macromolecules, such as proteins, by means of the diffraction of neutrons from the regularly spaced atoms of a crystal.

21 Jul 2016

Improving efficiency of health facilities could extend ART to many people living with HIV

Health facilities in Kenya, Uganda, and Zambia could extend life-sustaining antiretroviral therapy (ART) to hundreds of thousands of people living with HIV if facilities improved the efficiency of service delivery.

21 Jul 2016

Study provides new insights into real-world use of PrEP

Several studies presented today in an official press conference at the 21st International AIDS Conference in Durban provided new insights on the use of PrEP among a broad range of populations.

21 Jul 2016

GSK and University of Leicester team up to develop novel drugs to treat blood cancer

A collaboration between the University of Leicester and global pharmaceutical company GlaxoSmithKline has been established to discover and develop novel medicines to treat aggressive forms of blood cancer.

21 Jul 2016

Long-term antibiotic treatment slows progression of Alzheimer's disease through changes in gut bacteria

Long-term treatment with broad spectrum antibiotics decreased levels of amyloid plaques, a hallmark of Alzheimer's disease, and activated inflammatory microglial cells in the brains of mice in a new study by neuroscientists from the University of Chicago.

21 Jul 2016

Scientific review cautions against unnecessary use of antioxidant supplements

The lay press and thousands of nutritional products warn of oxygen radicals or oxidative stress and suggest taking so-called antioxidants to prevent or cure disease.

21 Jul 2016

TSRI study reveals new approach to intervene in deadly disease

In a new study, scientists at The Scripps Research Institute have identified drug candidates that can boost a cell's ability to catch the "typos" in protein production that can cause a deadly disease called amyloidosis.

From Paxman 21 Jul 2016

Penn researchers develop plant-based oral vaccine booster

Jonas Salk created a vaccine against polio that has been used since 1955; Albert Sabin created another version that has been on the market since 1961. Together, these two vaccines have nearly eliminated polio from the face of the earth.

20 Jul 2016

Study confirms efficacy of PrEP in reducing risk of HIV infection in men who have sex with men

The last phase of ANRS IPERGAY has confirmed that "on-demand" pre-exposure prophylaxis (PrEP) is a highly effective method of reducing the risk of HIV infection in men who have sex with men and who report high-risk behavior.

20 Jul 2016

Researchers find dangerous antibiotic-resistant bacteria in wastewater from broken sewer lines

University of South Florida researchers investigating the aftermath of a September, 2014 sewer line break in St. Petersburg, Florida, have found dangerous antibiotic-resistant bacteria in the untreated wastewater that gushed into neighborhoods and into Boca Ciega Bay at a rate of 250 to 500 gallons per minute.

20 Jul 2016

Risk of hypoglycemia differs between SU agents, study reveals

Adding sulphonylureas (SUs) to metformin remains a commonly used strategy for treating type 2 diabetes, but individual SUs differ and may confer different risks of abnormally low blood sugar, or hypoglycemia. SUs-which include newer generation agents such as gliclazide, glipizide, glimepiride, and glibenclamide-stimulate the production of insulin in the pancreas and increase the effectiveness of insulin in the body.

20 Jul 2016

Antibiotic usage, infections may contribute to manic episodes in people with mental disorders

In research using patient medical records, investigators from Johns Hopkins and Sheppard Pratt Health System report that people with serious mental disorders who were hospitalized for mania were more likely to be on antibiotics to treat active infections than a group of people without a mental disorder.

20 Jul 2016

ART could help reduce opportunistic infections and save lives of HIV-infected children

According to the World Health Organization (WHO), 150,000 children with HIV under 15 years of age died of opportunistic infections in low-to-middle income countries in 2014 alone.

20 Jul 2016

Antipsychotic drug could help reduce nausea and vomiting caused by chemotherapy

A drug that blocks neurotransmitters could reduce nausea and vomiting caused by chemotherapy, research co-authored by a Sanford Health physician and published in the New England Journal of Medicine finds.

20 Jul 2016

Study explores rate of antipsychotic polypharmacy among patients discharged from psychiatric hospitals

In recent years, measures have been introduced to reduce the rate of "antipsychotic polypharmacy"—taking more than one antipsychotic drug—among patients with schizophrenia and other serious mental illnesses.

20 Jul 2016

Researchers develop antibody with potential therapeutic effects against multiple sclerosis

Inserm Unit U919, directed by Prof. Denis Vivien has developed an antibody with potential therapeutic effects against multiple sclerosis.

20 Jul 2016

Study pinpoints how immune abnormalities in retina may lead to macular degeneration

In a study published this week in the Proceedings of the National Academy of Sciences, a University of Wisconsin-Madison research team pinpoints how immune abnormalities beneath the retina result in macular degeneration, a common condition that often causes blindness.

19 Jul 2016

Pharmaceutical News

Texas Biomed scientists receive $23 million NIH grant to develop AIDS vaccine

Patients with cLBP more likely to use illicit drugs, study reports

BET inhibitor treatment decreases lung inflammation in mice

Neutrons key to discovering new HIV drugs? An interview with Dr Matthew Blakeley

Improving efficiency of health facilities could extend ART to many people living with HIV

Study provides new insights into real-world use of PrEP

GSK and University of Leicester team up to develop novel drugs to treat blood cancer

Long-term antibiotic treatment slows progression of Alzheimer's disease through changes in gut bacteria

Scientific review cautions against unnecessary use of antioxidant supplements

TSRI study reveals new approach to intervene in deadly disease

Penn researchers develop plant-based oral vaccine booster

Study confirms efficacy of PrEP in reducing risk of HIV infection in men who have sex with men

Researchers find dangerous antibiotic-resistant bacteria in wastewater from broken sewer lines

Risk of hypoglycemia differs between SU agents, study reveals

Antibiotic usage, infections may contribute to manic episodes in people with mental disorders

ART could help reduce opportunistic infections and save lives of HIV-infected children

Antipsychotic drug could help reduce nausea and vomiting caused by chemotherapy

Study explores rate of antipsychotic polypharmacy among patients discharged from psychiatric hospitals

Researchers develop antibody with potential therapeutic effects against multiple sclerosis

Study pinpoints how immune abnormalities in retina may lead to macular degeneration

PhD researcher at LifeArc

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