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Easy, immediate access to effective antidotes could help reduce deaths from opioid overdose

Over the past 15 years, deaths caused by heroin and prescription opioid overdoses have quadrupled despite the existence of a highly effective antidote. The cover story in Chemical & Engineering News, the weekly news magazine of the American Chemical Society, explores what it might take to turn the tide.

19 May 2016

Neurotoxic effects of chemotherapy may impair cognitive function in young ALL patients

The neurotoxic effects of chemotherapeutic drugs on the developing brains of young patients with acute lymphoblastic leukemia (ALL) may impair their cognitive functioning by disrupting the formation of neural networks that connect brain regions and transfer information.

19 May 2016

Melatonin can be of great value for elderly people suffering from hypertension

The older we get, the more likely our circadian rhythms are disrupted. For example, blood pressure (BP), not only tends to increase but as well become more irregular. Luckily, as we show in our research, melatonin helps to ameliorate both trends.

18 May 2016

Take complementary medicines with care

Following the broadcast of the ABC’s Four Corners episode last night on complementary medicines, NPS MedicineWise is reminding people to take these medicines with care.

18 May 2016

Prenatal exposure to SSRIs linked to lower birth weight, gestational length

A new study, published today in the International Journal of Epidemiology, has found that prenatal exposure to selective serotonin reuptake inhibitors (SSRIs) has a significant association with lower birth weight and gestational length.

17 May 2016

Novel therapeutic approach to treat leukaemia patients

Cancer cells have an abnormal cell division and survival machinery - they grow faster than they die. For their permanent development, they produce an excess of growth factors and nutrients and block the body's own safety mechanisms.

17 May 2016

Experimental hepatitis C drug slows down development of Zika in mice

Virologists from KU Leuven, Belgium, have shown that an experimental antiviral drug against hepatitis C slows down the development of Zika in mice. The research team was led by Professor Johan Neyts from the Laboratory of Virology and Chemotherapy.

17 May 2016

Antipsychotic drug users may twice as likely to experience heart attack than non-users

A review of nine observational studies found evidence supporting an increased risk of heart attacks in patients taking antipsychotic drugs.

17 May 2016

FDA approves additional indication for Eisai's anticancer agent Lenvima in combo with Everolimus for advanced renal cell carcinoma

Eisai Co., Ltd. has announced that its U.S. subsidiary Eisai Inc. has received approval from the U.S. Food and Drug Administration (FDA) for an additional indication for Eisai's in-house developed novel anticancer agent Lenvima (lenvatinib mesylate) in combination with everolimus for the treatment of patients with advanced renal cell carcinoma following one prior anti-angiogenic therapy.

16 May 2016

Pluristem completes enrollment in Phase II intermittent claudication trial

Pluristem Therapeutics Inc., a leading developer of placenta-based cell therapy products, today announced it has completed the planned enrollment of 150 patients in a global Phase II trial of its PLacental eXpanded (PLX)-PAD cells for the treatment of intermittent claudication (IC), a peripheral artery disease (PAD). The double blind, randomized, placebo controlled trial enrolled 50 patients since October 2015 in the U.S., Germany, Israel, and South Korea.

16 May 2016

Neos announces U.S. launch of Adzenys XR-ODT for ADHD

Neos Therapeutics, Inc., a pharmaceutical company with a late‐stage pipeline of innovative extended-release (XR) product candidates for the treatment of attention-deficit/hyperactivity disorder (ADHD), today announced that Adzenys XR-ODT™ is in distribution channels and is now available to prescribe for patients with ADHD in the United States.

16 May 2016

Boehringer Ingelheim presents new data on OFEV® (nintedanib) in idiopathic pulmonary fibrosis (IPF)

New analyses presented at the American Thoracic Society’s 2016 annual conference (ATS 2016) further add to the efficacy and safety profile of OFEV® (nintedanib) in idiopathic pulmonary fibrosis (IPF).

16 May 2016

Combination of COX-2-selective NSAID with PPI can reduce risk of stomach, intestinal ulcers

Non-steroidal anti-inflammatory drugs (NSAIDs)—including ibuprofen, diclofenac, naproxen and others—are commonly used pain medications that are generally safe but may increase the risk of developing stomach and intestinal ulcers.

13 May 2016

BetterYou Magnesium Oil spray relieves migraine pain in 43-year old mum

A 43-year old mum of one from Bristol, who suffered from frequent painful migraines for almost a decade has found relief thanks to BetterYou™ Magnesium Oil spray.

From BetterYou Ltd 13 May 2016

Rotavirus vaccine program reduces hospitalization rates by more than 70% in Ontario

Hospitalization for rotavirus infections decreased by > 70% following the introduction of a vaccine program in Ontario, Canada, according to a study published May 11, 2016 in the open-access journal PLOS ONE by Sarah Wilson from Public Health Ontario and the Institute for Clinical Evaluative Sciences, Canada, and colleagues.

13 May 2016

New research solves mystery of why cetuximab drug proved futile for many colorectal cancer patients

Cancer researchers have identified a marker that shows up in a blood test that determines which patients with colorectal cancer that has spread would benefit from receiving the drug cetuximab.

13 May 2016

General anesthesia affects heart muscle proteins and causes depressed heart function, study shows

Anesthesia is used every day, but surprisingly little is known about one of its most dangerous side effects--depressed heart function.

13 May 2016

Estrogen-inhibiting drug may suppress dangerous brain seizures

A class of drug that inhibits estrogen production and is used to treat breast cancer has been found to quickly and effectively suppress dangerous brain seizures, according to a new Northwestern University study.

13 May 2016

High level of folate in mothers may double infant's chances of developing autism

Women who plan on becoming pregnant are told they need enough of the nutrient folate to ensure proper neurodevelopment of their babies, but new research from the Johns Hopkins Bloomberg School of Public Health suggests there could be serious risks in having far too much of the same nutrient.

12 May 2016

Same-day initiation of antiretroviral therapy for HIV patients may lead to better health outcomes

A clinical trial of same-day initiation of antiretroviral therapy (ART) for HIV patients in South Africa led to a higher proportion of people starting treatment and to better health outcomes, according to a new study led by a Boston University School of Public Health researcher.

12 May 2016

Pharmaceutical News

Easy, immediate access to effective antidotes could help reduce deaths from opioid overdose

Neurotoxic effects of chemotherapy may impair cognitive function in young ALL patients

Melatonin can be of great value for elderly people suffering from hypertension

Take complementary medicines with care

Prenatal exposure to SSRIs linked to lower birth weight, gestational length

Novel therapeutic approach to treat leukaemia patients

Experimental hepatitis C drug slows down development of Zika in mice

Antipsychotic drug users may twice as likely to experience heart attack than non-users

FDA approves additional indication for Eisai's anticancer agent Lenvima in combo with Everolimus for advanced renal cell carcinoma

Pluristem completes enrollment in Phase II intermittent claudication trial

Neos announces U.S. launch of Adzenys XR-ODT for ADHD

Boehringer Ingelheim presents new data on OFEV® (nintedanib) in idiopathic pulmonary fibrosis (IPF)

Combination of COX-2-selective NSAID with PPI can reduce risk of stomach, intestinal ulcers

BetterYou Magnesium Oil spray relieves migraine pain in 43-year old mum

Rotavirus vaccine program reduces hospitalization rates by more than 70% in Ontario

New research solves mystery of why cetuximab drug proved futile for many colorectal cancer patients

General anesthesia affects heart muscle proteins and causes depressed heart function, study shows

Estrogen-inhibiting drug may suppress dangerous brain seizures

High level of folate in mothers may double infant's chances of developing autism

Same-day initiation of antiretroviral therapy for HIV patients may lead to better health outcomes

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