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Nutritional supplements can enhance effectiveness of antidepressants

An international evidence review has found that certain nutritional supplements can increase the effectiveness of antidepressants for people with clinical depression.

26 Apr 2016

Study identifies risk factors for asparaginase-induced pancreatitis in ALL patients

Researchers have identified a rare genetic variation associated with a dramatically increased risk of severe acute pancreatitis in acute lymphoblastic leukemia (ALL) patients treated with the chemotherapy agent asparaginase. St. Jude Children's Research Hospital led the study, which appears today in the Journal of Clinical Oncology.

26 Apr 2016

High doses of commonly-used chemotherapy drug may increase survival rate of ALL patients

With a cure rate approaching 90 percent, acute lymphoblastic leukemia (ALL) - the most common type of childhood cancer - is often hailed as one of the "success stories" of modern cancer treatment. But up to 20 percent of patients with a high risk of relapse are not cured. That could change with the results from a clinical trial co-led by investigators from NYU Langone Medical Center, which shows giving high doses of a commonly-used chemotherapy drug increases the survival rate for these patients.

26 Apr 2016

New study explores factors that affect Medicare patient’s adherence to psoriasis biologic therapies

About half of Medicare patients who start taking biologic therapies for moderate to severe plaque psoriasis stop within a year, according to a new study led by researchers from the Perelman School of Medicine at the University of Pennsylvania.

26 Apr 2016

Criminology theory to combat counterfeit, sub-standard medicines

Around the world, especially in developing nations, counterfeit medicines are a real problem. Until now, in many countries there hasn't been a standard protocol to conduct investigations and pursue prosecution.

26 Apr 2016

Hydrocortisone drug can also prevent lung damage in premature babies

Research from Ann & Robert H. Lurie Children's Hospital of Chicago conducted in mice shows the drug hydrocortisone -- a steroid commonly used to treat a variety of inflammatory and allergic conditions -- can also prevent lung damage that often develops in premature babies treated with oxygen.

26 Apr 2016

New dietary supplement may offer hope to combat heart disease

Combining marine fish oil, cocoa extract and phytosterols into a dietary supplement could offer new hope in the fight against heart disease, a new study suggests.

25 Apr 2016

First breakthrough in gene therapy against aging

In September 2015, then 44 year-old CEO of BioViva USA Inc. Elizabeth Parrish received two of her own company's experimental gene therapies: one to protect against loss of muscle mass with age, another to battle stem cell depletion responsible for diverse age-related diseases and infirmities.

25 Apr 2016

Targeted therapy for triple-negative breast cancer may prove beneficial

A targeted therapy for triple-negative breast cancer (TNBC), the most aggressive form of breast cancer, has shown potential promise in a recently published study. TNBC is the only type of breast cancer for which there are no currently approved targeted therapies.

22 Apr 2016

Rituximab drug more effective than fingolimod for patients with highly active multiple sclerosis

A new study indicates that rituximab is more effective than fingolimod for preventing relapses in patients with highly active multiple sclerosis switching from treatment with natalizumab.

22 Apr 2016

New molecule-building method may have great impact on pharmaceutical industry

Scientists at The Scripps Research Institute (TSRI) have devised a new molecule-building method that is likely to have a major impact on the pharmaceutical industry and many other chemistry-based enterprises.

22 Apr 2016

PPP3CA, calcineurin may be suitable therapeutic targets for multiple myeloma treatment

Multiple myeloma (MM) is a hematological cancer that frequently acquires resistance to chemotherapeutic drugs. Additionally, many patients experience disease relapse, but these patients are difficult to treat as the cancer is often resistant to the previous treatment regimen.

22 Apr 2016

Infected mice can be better models for human diseases

Vaccines and therapeutics developed using mice often don't work as expected in humans. New research at Washington University School of Medicine in St. Louis points to the near-sterile surroundings of laboratory mice as a key reason.

21 Apr 2016

Novel combination of cancer drugs can have therapeutic impact on diffuse large B-cell lymphoma

New research from Roswell Park Cancer Institute shows that promising cancer drugs used in combination can have significant therapeutic impact on a particularly aggressive subtype of diffuse large B-cell lymphoma (DH-DLBCL) in preclinical studies. The researchers will present their findings at the American Association for Cancer Research (AACR) Annual Meeting 2016, to be held April 16-20 in New Orleans.

21 Apr 2016

TSRI chemists develop new method to achieve chemical reaction in pharmaceutical industry

Scientists at The Scripps Research Institute have found a new and better way to achieve a chemical reaction that is used widely in the pharmaceutical as well as flavor and fragrance industries.

21 Apr 2016

Motivational interviewing can help reduce risky use of pain pills

As America battles an epidemic of deaths from misused pain pills, a new study suggests an inexpensive way to cut risky use of these drugs by people who have a high chance of overdosing.

21 Apr 2016

Drugs that block NOTCH signaling in many cancers could be effective against ACC

Using a novel cell culture approach, Yale Cancer Center researchers have discovered critical vulnerabilities in adenoid cystic carcinoma (ACC), a rare and lethal glandular cancer with a high recurrence rate and few treatment options.

21 Apr 2016

Clinical study shows watercress extract inhibits carcinogen activation in cigarette smokers

Watercress extract taken multiple times a day significantly inhibits the activation of a tobacco-derived carcinogen in cigarette smokers, researchers at the University of Pittsburgh Cancer Institute, partner with UPMC Cancer Center, demonstrated in a phase II clinical trial presented today at the American Association for Cancer Research Annual Meeting in New Orleans.

21 Apr 2016

Researchers reposition existing prazosin drug to combat glioblastoma

Treatments available for glioblastoma—malignant brain tumors—have little effect. An international collaboration led by the Laboratoire Neurosciences Paris-Seine tested active ingredients from existing medications and eventually identified one compound of interest, prazosin, on these tumors. Not only did it seem to be effective in this type of cancer, but it also acted on a signaling pathway that is common with other cancers.

21 Apr 2016

Antidepressant Wellbutrin linked to long-term modest weight loss

Group Health researchers have found that bupropion (marketed as Wellbutrin) is the only antidepressant that tends to be linked to long-term modest weight loss.

21 Apr 2016

Pharmaceutical News

Nutritional supplements can enhance effectiveness of antidepressants

Study identifies risk factors for asparaginase-induced pancreatitis in ALL patients

High doses of commonly-used chemotherapy drug may increase survival rate of ALL patients

New study explores factors that affect Medicare patient’s adherence to psoriasis biologic therapies

Criminology theory to combat counterfeit, sub-standard medicines

Hydrocortisone drug can also prevent lung damage in premature babies

New dietary supplement may offer hope to combat heart disease

First breakthrough in gene therapy against aging

Targeted therapy for triple-negative breast cancer may prove beneficial

Rituximab drug more effective than fingolimod for patients with highly active multiple sclerosis

New molecule-building method may have great impact on pharmaceutical industry

PPP3CA, calcineurin may be suitable therapeutic targets for multiple myeloma treatment

Infected mice can be better models for human diseases

Novel combination of cancer drugs can have therapeutic impact on diffuse large B-cell lymphoma

TSRI chemists develop new method to achieve chemical reaction in pharmaceutical industry

Motivational interviewing can help reduce risky use of pain pills

Drugs that block NOTCH signaling in many cancers could be effective against ACC

Clinical study shows watercress extract inhibits carcinogen activation in cigarette smokers

Researchers reposition existing prazosin drug to combat glioblastoma

Antidepressant Wellbutrin linked to long-term modest weight loss

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