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New research links antibiotic use before age 2 to childhood obesity

While early antibiotic use has been associated with a number of rare long-term health consequences, new research links antibiotics to one of the most important and growing public health problems worldwide -- obesity.

23 Mar 2016

Antipsychotic medications may not be effective in preventing delirium in hospitalized patients

A recent review of the medical literature does not support the use of antipsychotic medications for preventing or treating delirium in hospitalized patients.

23 Mar 2016

Subcutaneous injection of raltegravir can protect against vaginal HIV transmission

Vaginal transmission accounts for the majority of new HIV infections worldwide. Forms of pre-exposure prophylaxis (PrEP) such as vaginal gels and vaginal rings designed to prevent HIV transmission have encountered poor efficacy in human trials due to problems with adherence.

22 Mar 2016

Tiny gel slivers open way to personalised cancer treatment targeting particular tumour

They look like small, translucent gems but these tiny 'gel' slivers hold the world of a patient's tumour in microcosm ready for trials of anti-cancer drugs to find the best match between treatment and tumour.

22 Mar 2016

Scientists look for new antibiotic drugs in unexpected places

Many of the drugs we use in hospitals – antibiotics, antifungals and anti-cancer drugs, to name but a few – are produced by bacteria that live in the soil beneath our feet.

22 Mar 2016

Mycophenolate mofetil drug seems safe, effective in treating autoimmune hepatitis

New research indicates that mycophenolate mofetil, a drug that is usually used to prevent rejection after kidney, heart or liver transplant, seems safe and effective in treating autoimmune hepatitis (AIH), a serious chronic liver disease that mainly affects women.

22 Mar 2016

Antipsychotic drugs may do significantly more harm to Parkinson's disease patients

At least half of Parkinson's disease patients experience psychosis at some point during the course of their illness, and physicians commonly prescribe antipsychotic drugs, such as quetiapine, to treat the condition. However, a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania, the University of Michigan Medical School, and the Philadelphia and Ann Arbor Veterans Affairs Medical Centers and suggests that these drugs may do significantly more harm in a subset of patients.

21 Mar 2016

Anthim (obiltoxaximab) injection approved for treatment of inhalational anthrax

On Friday, March 18, the U.S. Food and Drug Administration approved Anthim (obiltoxaximab) injection to treat inhalational anthrax in combination with appropriate antibacterial drugs. Anthim is also approved to prevent inhalational anthrax when alternative therapies are not available or not appropriate.

21 Mar 2016

Real-world studies support switching IBD patients from reference infliximab to biosimilar infliximab

Data presented today at the 11th Congress of European Crohn’s and Colitis Organisation adds to the growing body of real-world evidence that supports switching patients from reference infliximab to biosimilar infliximab.

21 Mar 2016

LEO Pharma announces scientific approval of Enstilar for treatment of people living with psoriasis in EU

LEO Pharma today announced that it received scientific approval of Enstilar (calcipotriol/betamethasone dipropionate 50 micrograms/g / 0,5 mg/g) for the treatment of psoriasis vulgaris in patients 18 years of age or older.

21 Mar 2016

Women taking birth control pill less likely to suffer serious knee injuries

Researchers from The University of Texas Medical Branch at Galveston have found that women who take the birth control pill, which lessen and stabilize estrogen levels, were less likely to suffer serious knee injuries. The findings are currently available in Medicine & Science in Sports & Exercise, the official journal of the American College of Sports Medicine.

21 Mar 2016

Study assesses acceptability of alternative drug to prevent malaria among pregnant women in Kenya

Researchers at LSTM, working with colleagues at the Centres for Disease Control and Prevention USA, the Kenya Medical Research Institute, and from the London School of Hygiene and Tropical Medicine, have completed a study to assess the acceptability among pregnant women and health providers in Kenya of a new drug as an alternative to the standard drug used to prevent malaria in pregnancy.

21 Mar 2016

Study: Cox2 inhibition improves outcomes in preeclampsia-like mouse model

Preeclampsia is characterized by elevated blood pressure in the second half of pregnancy and impaired blood flow to the placenta, which increases the risk of premature birth and pregnancy complications.

21 Mar 2016

Research shows how recreational ketamine abuse harms the bladder

Research conducted by scientists at the University of York has revealed how recreational ketamine abuse damages the bladder

21 Mar 2016

Novel compound shows promise as potential treatment for acute myeloid leukemia

A novel compound has shown promise in preclinical studies as a treatment for acute myeloid leukemia, more than doubling median days of survival even in a drug-resistant form of the disease.

21 Mar 2016

MRX-2843 treatment improves survival of acute myeloid leukemia patients

Acute myeloid leukemia (AML) is a cancer of myeloid stem cells that develops in both adult and pediatric populations. Mutations that cause hyperactivation of the FMS-like tyrosine kinase 3 (FLT3) are commonly found in AML, and several clinical trials are testing FLT3 inhibitors.

21 Mar 2016

Trimeprazine improves β cell function, slows progression of diabetes

β cells in pancreatic islets are responsible for producing insulin, which is essential to regulate blood glucose homeostasis. In type 1 diabetes, pancreatic β cells are destroyed due to an autoimmune attack, whereas in type 2 diabetes, pancreatic β cells may have deficiencies in secreting insulin or insulin-responding tissues can become insulin resistant.

21 Mar 2016

Cobimetinib with vemurafenib may have added benefit in melanoma with BRAF V600 mutation

Cobimetinib (trade name: Cotellic) has been approved since November 2015 in combination with vemurafenib for the treatment of adults with advanced, i.e. metastatic or unresectable, melanoma with a BRAF V600 mutation.

21 Mar 2016

Penn study calls on physicians to avoid over-prescribing opioids for surgical patients

Physicians are prescribing more opioid painkillers than ever before to patients undergoing common surgeries, according to new research from the department of Anesthesiology and Critical Care at the Perelman School of Medicine at the University of Pennsylvania.

21 Mar 2016

Paracetamol does not meet minimum standard of clinical effectiveness in osteoarthritis patients

In a large-scale analysis of pain-relief medication for osteoarthritis, researchers found that paracetamol does not meet the minimum standard of clinical effectiveness in reducing pain or improving physical function in patients with knee and hip osteoarthritis.

18 Mar 2016

Pharmaceutical News

New research links antibiotic use before age 2 to childhood obesity

Antipsychotic medications may not be effective in preventing delirium in hospitalized patients

Subcutaneous injection of raltegravir can protect against vaginal HIV transmission

Tiny gel slivers open way to personalised cancer treatment targeting particular tumour

Scientists look for new antibiotic drugs in unexpected places

Mycophenolate mofetil drug seems safe, effective in treating autoimmune hepatitis

Antipsychotic drugs may do significantly more harm to Parkinson's disease patients

Anthim (obiltoxaximab) injection approved for treatment of inhalational anthrax

Real-world studies support switching IBD patients from reference infliximab to biosimilar infliximab

LEO Pharma announces scientific approval of Enstilar for treatment of people living with psoriasis in EU

Women taking birth control pill less likely to suffer serious knee injuries

Study assesses acceptability of alternative drug to prevent malaria among pregnant women in Kenya

Study: Cox2 inhibition improves outcomes in preeclampsia-like mouse model

Research shows how recreational ketamine abuse harms the bladder

Novel compound shows promise as potential treatment for acute myeloid leukemia

MRX-2843 treatment improves survival of acute myeloid leukemia patients

Trimeprazine improves β cell function, slows progression of diabetes

Cobimetinib with vemurafenib may have added benefit in melanoma with BRAF V600 mutation

Penn study calls on physicians to avoid over-prescribing opioids for surgical patients

Paracetamol does not meet minimum standard of clinical effectiveness in osteoarthritis patients

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