T Cell News and Research

Latest T Cell News and Research

Scientists solve arsenic's cancer paradox

Cancer Research UK scientists have discovered how arsenic works as an effective treatment for leukaemia - according to a report in Nature Cell Biology.

15 Apr 2008

Regulating hematopoietic stem cell homeostasis and leukemogenesis

In the April 15th issue of G&D, Dr. Richard Flavell (Yale University) and colleagues identify the c-Cbl protein as a critical repressor of hematopoietic stem cell (HSC) self-renewal.

15 Apr 2008

NovoCure presents results from breast cancer pilot study

NovoCure announced today that it presented the results from a single-arm pilot trial evaluating the Novo-TTF, a non-invasive portable medical device, combined with neo-adjuvant chemotherapy for the treatment of patients with locally advanced breast cancer.

15 Apr 2008

Drug-treated blood stem cells used to repair heart damage in animal model

Researchers at UT Southwestern Medical Center have for the first time used drug-treated blood stem cells to repair heart damage in an animal model, results that might point to methods for healing injuries from heart attacks or disease.

15 Apr 2008

New insight into the pathogenesis of neurodegeneration in Ataxia telangiectasia

An upcoming paper from Dr. David Wassarman (University of Wisconsin School of Medicine and Public Health) in the May 1 issue of G&D lends new insight into the pathogenesis of neurodegeneration in Ataxia telangiectasia.

15 Apr 2008

Why cigarette are smokers at higher risk of developing pancreatic cancer?

If lung cancer and heart disease aren't bad enough, cigarette smokers are also at higher risk for developing, among other things, pancreatic cancer.

15 Apr 2008

Stem cell marker controls two key cancer pathways

Researchers at Georgetown University Medical Center have discovered that a gene associated with human breast stem cells can stimulate development of mammary cells by activating two critical cancer pathways.

15 Apr 2008

Profoundly important discovery of differences in heart's precursor cells

Scientists have long thought that the cells that ultimately give rise to the heart all respond to the same cue before turning into the muscle tissue of this vital organ.

15 Apr 2008

Lipitor and Celebrex combined may halt prostate cancer

Researchers at Rutgers' Ernest Mario School of Pharmacy have shown that administering a combination of the widely used drugs Celebrex (celecoxib, a nonsteroidal anti-inflammatory drug) and Lipitor (atorvastatin, a cholesterol lowering drug) stops the transition of early prostate cancer to its more aggressive and potentially fatal stage.

15 Apr 2008

Cancer prevention

Tapping into a growing body of knowledge about the origins and progression of cancer, researchers are now developing and testing new preventive therapies to stop it in its tracks.

15 Apr 2008

Restricted-calorie diets limit development of epithelial cancers

A restricted-calorie diet inhibited the development of precancerous growths in a two-step model of skin cancer, reducing the activation of two signaling pathways known to contribute to cancer growth and development, researchers at The University of Texas M. D. Anderson Cancer Center report today at the American Association for Cancer Research annual meeting.

15 Apr 2008

Blood pressure drugs halt pancreatic cancer cell growth

Researchers at the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia are inching closer to understanding how common blood pressure medications might help prevent the spread of pancreatic cancer.

15 Apr 2008

New hope for blood disorder anaemia

A new understanding of how red blood cell production is controlled could lead to improvements in the treatment of the blood disorder anaemia, according to West Australian medical researchers.

13 Apr 2008

Stopping unwanted cell death: novel avenue for drug development

Research published in Nature Chemical Biology reveals that three specific inhibitors of a cell death pathway, termed necroptosis, all target and inhibit RIP1 kinase, a protein that can direct cells into necrosis.

13 Apr 2008

Bone stem cells offer cartilage repair hope for arthritis sufferers

Research being presented at the UK National Stem Cell Network Annual Science Meeting in Edinburgh could offer hope that bone stem cells may be harnessed to repair the damaged cartilage that is one of the main symptoms of osteoarthritis.

13 Apr 2008

Stem cells and their role in malignant brain tumours

Speaking at the UK National Stem Cell Network Annual Science Meeting in Edinburgh, Professor Silvia Marino shows how the mechanisms normally involved in balancing different functions of stem cells may also contribute to cancer.

13 Apr 2008

Researchers study Rituximab's action on cancer stem cells

Preliminary data from one of the first clinical trials to test a stem cell-targeting drug in cancer patients shows that while the drug did not prolong survival, its suppressing effect on patients' stem cells was impressive enough to send investigators looking for a better drug to try.

13 Apr 2008

Targeted therapy combo overcomes treatment resistance in liver cancer

Researchers at the University of Pennsylvania School of Medicine and Abramson Cancer Center reported at the annual meeting of the American Association for Cancer Research that combining two targeted therapies overcomes treatment resistance in liver cancer cell lines.

13 Apr 2008

Targeted therapies overcome treatment resistance in liver cancer cell lines

Researchers at the University of Pennsylvania School of Medicine and Abramson Cancer Center reported today at the annual meeting of the American Association for Cancer Research that combining two targeted therapies overcomes treatment resistance in liver cancer cell lines.

13 Apr 2008

West Australians above the age of 69 at risk of sun-related skin cancer death

A new Western Australian study has revealed the mortality from non-melanoma skin cancer (NMSC), commonly considered less dangerous than melanoma, is affecting older Australians at a worrying rate.

13 Apr 2008